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Effects of inflammation-associated acute-phase response on hepatic and renal indices in the horse 总被引:1,自引:0,他引:1
Objectives To determine the effect of an acute soft tissue inflammatory response on biochemical and haematological indices of hepatic and renal function in the Thoroughbred horse.
Procedure Soft tissue inflammation was induced in four Thoroughbred horses by intramuscular injections of Freunds complete adjuvant. The horses were clinically examined and blood and urine samples were collected before and after the adjuvant injections. Biochemical and haematological indices were measured in samples collected and used to determine the onset of the acute-phase response and to assess hepatic and renal function at this time.
Results After adjuvant injection, significant increases (P< 0.01) in total white (13.1 ± 1.4 times 109 /L) and neutrophil (10.2 ± 1.2 times109/L) cell counts, rectal temperature (39.7 ± 0.5A°C) and various plasma protein concentrations, including fibrinogen (6.6 ± 1.2 g/L), haptoglobin (1.3 ± 0.1 g/L) and total protein (88.1 ± 2.7 g/L), indicated the induction of an acute-phase response. This corresponded with significant reductions (P< 0.01) in the plasma elimination half-lives (t½β) sodium bromo-sulphthalein (3.13 ± 0.05 to 2.82 ± 0.07 min) and sodium sulphanilate (38.29 ± 4.04 to 19.60 ± 5.68 min) and reductions in the plasma activities of aspartate aminotransferase, gluta-mate dehydrogenase, creatine kinase, alkaline phosphatase, gamma glutamyl transferase; the urinary creatinine clearance ratios of sodium, chloride and potassium; and the urinary gamma glutamyl transferase-to-creatinine clearance ratios. (All values mean ± SD.)
Conclusions The effects of the acute-phase response on indices of hepatic and renal function in the horse suggest that the disposition of pharmacological agents administered at this time may be altered and that indices of acute inflammation should be interpreted cautiously. 相似文献
Procedure Soft tissue inflammation was induced in four Thoroughbred horses by intramuscular injections of Freunds complete adjuvant. The horses were clinically examined and blood and urine samples were collected before and after the adjuvant injections. Biochemical and haematological indices were measured in samples collected and used to determine the onset of the acute-phase response and to assess hepatic and renal function at this time.
Results After adjuvant injection, significant increases (P< 0.01) in total white (13.1 ± 1.4 times 10
Conclusions The effects of the acute-phase response on indices of hepatic and renal function in the horse suggest that the disposition of pharmacological agents administered at this time may be altered and that indices of acute inflammation should be interpreted cautiously. 相似文献
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[目的]研究不同诱变剂量对棉花遗传变异的影响.[方法]利用100~300Gy的60Co-γ射线对5个陆地棉材料干种子进行辐射处理,对其M3、M4农艺经济性状的遗传变异进行分析.[结果]5个品种(系)在200Gy诱变剂量达到半致死剂量,200~300Gy是陆地棉理想的诱变剂量.M4群体的单铃重、单株铃数、株高和果枝数平均变异系数均超过10;以上,250Gy剂量诱变的辐射诱变后代M4群体表型性状变异系数存在明显差异.[结论]200~300Gy辐射剂量对不同棉花品种的诱变效果存在差异,揭示了辐射创造丰富的遗传变异. 相似文献
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Zohrah Haji SULAIMAN Tan Heok HUI Kelvin K.P. LIM Peter K.L. NG 《Integrative zoology》2006,1(1):12-14
Phylogenetic relationships among Bornean sucker fishes (Teleostei: Balitoridae: Gastromyzontinae) were investigated by comparing cytochrome b gene sequences from eight species. The results were in general agreement with previous morphology‐based studies. It was found that the genera Gastromyzon and Neogastromyzon are both monophyletic and that the Chinese homalopterid Crossostoma lacustre (Homalopterinae) is not related to the Bornean species. This molecular‐level study of cytochrome b gene variation in Bornean gastromyzontins will undoubtedly help to shed light on the molecular systematics of this unique freshwater fish. 相似文献
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聚丙烯酰胺防治坡地水土流失田间试验研究 总被引:14,自引:1,他引:13
坡地篱用聚丙烯酰胺可以减少地表径流,提高土壤含水量,促进土壤沉降,增强土壤结构性和水稳性,因而提高了土壤的持水性和抗蚀性,减少了土壤侵蚀量和肥力流失量,有利于作物增产。施用聚丙烯酰胺可使产量增加18.7%~32.4%。施用聚丙烯酰胺对环境无不良影响,而且投入费用较低,是一条值得探索的防治坡地水土流失的新途径。 相似文献
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Abstract. An assessment of the nutritive value of cassava as an energy source in a pelleted lilapia diet was carried out. Four isonitrogeneous diets containing 15%. 30%, 45% and 60% cassava were formulated and fed to groups of Ortochromis niloucus L for 10 weeks. Good growth and food utilization efficiencies were obtained with all diets: there was a trend of improved growth and food utilization with increased cassava incorporation in the diet although there were no significant differences (P < 0–05) in food conversion ratio, protein efficiency ratio or apparent net protein utilization between the experimental diets. No nutritionally related pathology was observed in fish fed high cassava levels. Increased incorporation of cassava led to an increase in the carcass fat content although it was within the acceptable limits for tilapia. Phytoplankton growth occurred in all experimental tanks due to the fertilization effects of uneaten feeds and faeces as the water within the experimental lankiyuem was not exchanged: the contribution of phytoplankton to the nutrition of the experimental fish was not quantified but was considered to be minimal since the phytoplankton biomass was approximately an order of magnitude less than in fertilized systems. 相似文献
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