Animal versus wind dispersal and the robustness of tree species to deforestation

Studies suggest that populations of different species do not decline equally after habitat loss. However, empirical tests have been confined to fine spatiotemporal scales and have rarely included plants. Using data from 89,365 forest survey plots covering peninsular Spain, we explored, for each of 34 common tree species, the relationship between probability of occurrence and the local cover of remaining forest. Twenty-four species showed a significant negative response to forest loss, so that decreased forest cover had a negative effect on tree diversity, but the responses of individual species were highly variable. Animal-dispersed species were less vulnerable to forest loss, with six showing positive responses to decreased forest cover. The results imply that plant-animal interactions help prevent the collapse of forest communities that suffer habitat destruction.     

Kinetics of morphogen gradient formation

In the developing fly wing, secreted morphogens such as Decapentaplegic (Dpp) and Wingless (Wg) form gradients of concentration providing positional information. Dpp forms a longer-range gradient than Wg. To understand how the range is controlled, we measured the four key kinetic parameters governing morphogen spreading: the production rate, the effective diffusion coefficient, the degradation rate, and the immobile fraction. The four parameters had different values for Dpp versus Wg. In addition, Dynamin-dependent endocytosis was required for spreading of Dpp, but not Wg. Thus, the cellular mechanisms of Dpp and Wingless spreading are different: Dpp spreading requires endocytic, intracellular trafficking.     

The forest conversion process: A discussion of the sustainability of predominant land uses associated with frontier expansion in the Amazon

One of the most striking features observed throughout tropical agricultural frontiers is the extreme variability in land-use strategies from one farmer to the next. This article analyzes the forest conversion process and predominant land uses associated with smallholder settlement expansion in the Amazon frontier. The discussion seeks to increase understanding of the micro and macro-level forces that propel land-use decisions in the Amazon and offer insights about how farmers' land-use decisions may be altered to bring about forms of resource use that are consistent with the constraints and opportunities of the frontier environment. Recognizing that no frontier area can be truly representative of the Amazon as a whole, this article also introduces some detailed evidence from another Amazon country (Ecuador) within a topic that has been previously dominated by research mainly in Brazil. The analysis suggests that to be effective, any policy or technology-based effort on the part of governments or researchers to alter colonist land-use systems must begin to look systematically at the production systems of agricultural colonist populations already present in frontier environments. This knowledge is essential to understand the social and economic factors affecting present land use and choice of technology. It is also important for understanding factors influencing farmers' demand for more optimal systems of land use that are consistent with varying agroecological potentials, demographic situations, and the management capacity of the farmer.     

Energetics of load carrying in Nepalese porters

Nepalese porters routinely carry head-supported loads equal to 100 to 200% of their body weight (Mb) for many days up and down steep mountain footpaths at high altitudes. Previous studies have shown that African women carry head-supported loads of up to 60% of their Mb far more economically than army recruits carrying equivalent loads in backpacks. Here we show that Nepalese porters carry heavier loads even more economically than African women. Female Nepalese porters, for example, carry on average loads that are 10% of their Mb heavier than the maximum loads carried by the African women, yet do so at a 25% smaller metabolic cost.     

Improved climate control for potato stores by fuzzy controllers

The main tasks for climate controllers in potato bulk stores are to keep the storage climate in an appropriate condition for quality conservation. To avoid extra energy costs by using cooling systems the internal climate of potato bulk stores is controlled with outdoor air. A conventionally designed controller is difficult to adapt for an optimal climate control to reduce quality loss. However, a controller designed with fuzzy logic is found as advantageous for adapting control parameters to improve the control process. A test stand is built to ventilate and to control two samples of potato bulks simultaneously with the same outdoor weather conditions for comparisons. Several experiments were carried out to compare climate controllers with different control algorithms, i.e. conventional to a different conventional and conventional to fuzzy.     

Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor

Because of its requirement for signaling by multiple cytokines, Janus kinase 3 (JAK3) is an excellent target for clinical immunosuppression. We report the development of a specific, orally active inhibitor of JAK3, CP-690,550, that significantly prolonged survival in a murine model of heart transplantation and in cynomolgus monkeys receiving kidney transplants. CP-690,550 treatment was not associated with hypertension, hyperlipidemia, or lymphoproliferative disease. On the basis of these preclinical results, we believe JAK3 blockade by CP-690,550 has potential for therapeutically desirable immunosuppression in human organ transplantation and in other clinical settings.     

Monte Verde: seaweed, food, medicine, and the peopling of South America

The identification of human artifacts at the early archaeological site of Monte Verde in southern Chile has raised questions of when and how people reached the tip of South America without leaving much other evidence in the New World. Remains of nine species of marine algae were recovered from hearths and other features at Monte Verde II, an upper occupational layer, and were directly dated between 14,220 and 13,980 calendar years before the present ( approximately 12,310 and 12,290 carbon-14 years ago). These findings support the archaeological interpretation of the site and indicate that the site's inhabitants used seaweed from distant beaches and estuarine environments for food and medicine. These data are consistent with the ideas that an early settlement of South America was along the Pacific coast and that seaweeds were important to the diet and health of early humans in the Americas.     

Frequent recombination in a saltern population of Halorubrum

Sex and recombination are driving forces in the evolution of eukaryotes. Homologous recombination is known to be the dominant process in the divergence of many bacterial species. For Archaea, the only direct evidence bearing on the importance or natural occurrence of homologous recombination is anecdotal reports of mosaicism from comparative genomic studies. Genetic studies, however, reveal that recombination may play a significant role in generating diversity among members of at least one archaeal group, the haloarchaea. We used multi-locus sequence typing to demonstrate that haloarchaea exchange genetic information promiscuously, exhibiting a degree of linkage equilibrium approaching that of a sexual population.