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131.
Mogi K Yonezawa T Chen DS Li JY Suzuki M Yamanouchi K Sawasaki T Nishihara M 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2004,66(9):1071-1078
Growth hormone (GH) is secreted in a pulsatile manner, but the underlying mechanisms of GH pulse generation remain to be resolved. In the present study, we investigated the relationship between GH pulses in the peripheral circulation and GH-releasing hormone (GHRH) and somatostatin (SRIF) profiles in the cerebrospinal fluid (CSF) of male goats. The effects of an intracerebroventricular (icv) injection of neuropeptide Y (NPY), galanin and ghrelin were also analyzed. Blood and CSF samples were collected every 15 min for 8 hr from the jugular vein and third ventricle, respectively. GH pulsatility in the goat was found to consist of distinct large pulses of 5 hr periodicity and small pulses of 1 hr periodicity. GHRH and SRIF in the CSF fluctuated in a pulsatile manner with 1 hr periodicity, and most of the descending phase of SRIF pulses were associated with the initiation of GH pulses. Icv injections of NPY, galanin and ghrelin stimulated GHRH release without affecting SRIF release. In addition, NPY suppressed, and galanin and ghrelin induced large GH pulses, although ghrelin was much more effective than galanin. These results suggest that an hourly fall in SRIF is involved in generating intrinsic circhoral rhythm of GH pulsatility. The mechanisms underlying the generation of large GH pulses of 5 hr periodicity remain unknown, while direct action of NPY and/or ghrelin on the pituitary might be involved. 相似文献
132.
Maeda S Okayama T Ohmori K Masuda K Ohno K Tsujimoto H 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2003,65(2):275-278
Thymus and activation-regulated chemokine (TARC) is a member of CC chemokine and plays an essential role in recruitment of CC chemokine receptor 4 positive Th2 cells to allergic lesion. To investigate the association of TARC in allergic inflammation of cats, a TARC cDNA was cloned from feline thymus by RT-PCR with 3' rapid amplification of cDNA ends (RACE) method. The feline TARC clone contained a full length open reading frame encoding 99 amino acids which shared 80.8%, 72.5%, 65.6% and 67.8% homology with dog, human, mouse and rat homologues, respectively. Expression of TARC mRNA was detected not only in thymus but also in spleen, lung, lymph node, kidney, small intestine, colon and skin of the normal cat tissues examined. Furthermore, it was found that TARC mRNA was strongly expressed in lesional skin of cats with eosinophilic plaque. The present results demonstrated that TARC might be involved in the pathogenesis of eosinophilic plaque in cats. 相似文献
133.
Kubota K Suzuki M Yamanouchi K Takahashi M Nishihara M 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2003,65(2):237-242
The expression of activin and inhibin has been demonstrated in the hypothalamus, but their physiological roles in the brain remain to be elucidated. In the present study, involvement of activin and inhibin in the regulation of food and water intake was examined. Male rats were deprived of food or water for 12 and 60 hr, and mRNA levels of activin/inhibin alpha, betaA and betaB subunits in the hypothalamus were estimated by RT-PCR. Gene expression of alpha subunit transiently decreased at 12 hr of food deprivation, while it did not change during water deprivation. Food and water deprivation for 60 hr increased mRNA levels of betaA and betaB subunits, respectively. These results indicated that gene expression of each subunit was independently regulated. Injection of activin A (0.5 and 4.0 microg) into the third ventricle decreased food intake. Water intake was suppressed by 4.0 microg, but not 0.5 microg, of activin A. Intracerebroventricular injection of inhibin A (0.5 and 4.0 microg) decreased water intake in a dose dependent manner without affecting food intake, suggesting that inhibin could act independently of activin. Taken together, it is suggested that activin and inhibin take part in the central regulation of nutrient and fluid balance, though further study is needed to determine precise molecular species involved. 相似文献
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135.
Fujimura M Ohmori K Masuda K Tsujimoto H Sakaguchi M 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2002,64(11):1069-1070
A dog with Japanese cedar (Cryptomeria japonica, CJ) pollinosis had oral allergy syndrome (OAS) after ingesting fresh tomato. The dog showed specific IgE to both CJ and tomato allergens. As a negative control, twenty dogs without atopic dermatitis that had no exposure to tomato and no specific IgE to CJ allergen were used. They had no specific IgE to tomato allergen. Furthermore, IgE cross-reactivity was observed between CJ and tomato allergens in the dog. We found that OAS induced by tomato exists in the dog and there is a relationship between CJ and tomato allergens. 相似文献
136.
Tomoko Sasaki Fumiyo Hayakawa Yasuhiro Suzuki Keitaro Suzuki Kazuyuki Okamoto Kaoru Kohyama 《Cereal Chemistry》2013,90(2):101-106
The textural properties of cooked waxy rice cakes made from four waxy rice varieties including the unique varieties Kantomochi 172 (K172) and BC3 with the property of rapid hardening were analyzed by instrumental and sensory methods. For the instrumental analysis, a compression test, adhesiveness test, and tensile test were conducted. The waxy rice cakes made from K172 and BC3 showed significantly higher compressive force and resistance to break under tensile load. Significant difference in amylopectin chain‐length distribution was observed between each variety, and this difference strongly reflected the hardness of waxy rice cakes. The peak area ratio of amylopectin branch chains with 6–12 degrees of polymerization negatively correlated with the compressive force required for 50 and 80% strain. Sensory evaluation showed that the waxy rice cakes made from these varieties had a significantly harder, less stretchable, less smooth surface, whereas the scores for adhesiveness and ease to cut off (hagire) were preferable to those for other rice varieties. 相似文献
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138.
Koji SUGITA Ayaka SHIMA Kaho TAKAHASHI Yasuyoshi MATSUDA Masaki MIYAJIMA Marin HIROKAWA Hirotaka KONDO Junpei KIMURA Genki ISHIHARA Keitaro OHMORI 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(6):984
A 7-year 6-month-old, castrated male Shiba dog presented with a 1-month history of lethargy, anorexia, vomiting, and frequent watery diarrhea. Weight loss, hypoalbuminemia, anemia, and leukocytosis were detected at the first visit. The dog was diagnosed with non-responsive enteropathy (NRE) based on clinical and histopathological examinations. Since the dog did not respond to the immunosuppressive drugs, fecal microbiota transplantation (FMT) was performed during the treatment with chlorambucil. A single endoscopic FMT into the cecum and colon drastically recovered clinical signs and clinicopathological abnormalities and corrected dysbiosis in the dog. No recurrence or adverse events were observed. The present case report suggests that FMT, possibly together with chlorambucil, might be a treatment option for NRE in Shiba dogs that have poorer prognosis compared with other dog breeds. 相似文献
139.
Tohya Yasuda Kazuyoshi Komeyama Keitaro Kato Yasushi Mitsunaga 《Fisheries Science》2012,78(2):229-235
We investigated the usefulness of acceleration loggers in aquaculture by examining net-cage use and metabolic rates in red
sea bream, Pagrus major. First, the fish’s metabolic rate (mg O2 kg−1 min−1) was measured with the logger in a swim tunnel at designated water velocities. We found that metabolic rate could be expressed
by using a linear regression model of the activity rate index (unitless min−1) derived from acceleration data. Using this equation, the field metabolic rates of three fish in a net cage were monitored
and were estimated at 14.1–15.0 kcal kg−1 day−1. The results suggested that 15–19% of energy from satiation feeding ration was consumed for metabolism and activity in the
net cage. The loggers showed orderly net-cage use by the fish. Tagged individuals used the whole cage from surface to bottom,
but individual fish that preferred the surface area rarely used the bottom, and vice versa. Metabolic rate increased significantly
with distance of the fish from their preferred depths. The logger provided information on the physiological and behavioral
responses of fish in a given breeding system, and its use should contribute to the design of practical aquaculture systems. 相似文献