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排序方式: 共有333条查询结果,搜索用时 15 毫秒
331.
Claro N. Mingala Satoru Konnai Fe A. Venturina Misao Onuma Kazuhiko Ohashi 《Research in veterinary science》2009,87(2):213-217
This study describes the quantification of cytokine expression of vaccinated water buffaloes with FMD inactivated vaccine. Using real-time PCR quantification assay, expression of Th1 (IL-2, IL-12p40, IFNγ); Th2 (IL-4, IL-10) and inflammatory (IL-6, TNFα) cytokines were quantified weekly for the entire three-week duration of the experiment. It was noted that IFNγ, IL-10 and TNFα had peaked on week three post-vaccination while the remaining cytokines peaked on the second week and decreased by the third week. The counteraction between IFNγ and IL-4 was noted as well as the possible suppressive action of IL-10 to that of IL-2 and IL-12, which is a common phenomenon between Th1 and Th2 cytokines. Synergy between TNFa and IL-6 was also observed. These findings suggest that within the immune system of water buffalo there is a dynamic cell-mediated and humoral interaction in response to immunogen. This assessment of the cytokine expressions is vital for the study of water buffalo disease progression and concurring protective immune responses. 相似文献
332.
Various physiological functions of dietary glucosylceramides (GlcCer) have been reported, such as preventing colon cancer
and improving skin barrier function. One potential GlcCer source used as a foodstuff is sea cucumber. In this study, our objective
was to determine the effect of dietary GlcCer prepared from sea cucumber on plasma and liver lipids in cholesterol-fed mice.
ICR mice were fed four different diets (control diet, sea cucumber GlcCer supplemented diet, high cholesterol supplemented
diet, and high cholesterol + sea cucumber GlcCer supplemented diet). Dietary GlcCer decreased total cholesterol significantly
in ICR mice. The mRNA expression of LDL receptor was increased significantly, while the expression of the gene CYP7A1, which is involved in bile acid formation, was decreased significantly compared with the control (diet without cholesterol).
These results suggest that the expression of the cholesterol homeostasis gene in liver is modulated due to the cholesterol
lowering effect of dietary GlcCer. 相似文献
333.
Tetsuichiro Funamoto Orio Yamamura Osamu Shida Kazuhiko Itaya Ken Mori Yoshiaki Hiyama Yasunori Sakurai 《Fisheries Science》2014,80(2):117-126
The Japanese Pacific stock (JPS) and the northern Japan Sea stock (JSS) of walleye pollock Theragra chalcogramma are mainly distributed in the Pacific Ocean and the Sea of Japan off northern Japan, respectively. This paper summarizes and compares the factors affecting the recruitment variability of these two stocks. Spawning season is from December to March for both stocks. JPS recruitment has a positive relationship with the water temperature in January and February, whereas that of JSS has a negative relationship with the water temperature in January, February, and April. One possible reason for this is that pollock larvae have an optimum growth temperature of approximately 5 °C in the field. Drift of early life stages also appears to be an important influence on the recruitment of both stocks. Because the current generated by the northwest wind carries eggs of JPS into the main larval nursery ground, JPS recruitment is enhanced in years when the northwest wind is predominant in February. On the other hand, early life stages of JSS are transported into the nursery ground by the Tsushima Warm Current. However, this current also carries early life stages into the Sea of Okhotsk and offshore, resulting in poor JSS recruitment in years when this current is strong in March. In contrast to JPS, the recruitment of which is significantly impacted by cannibalism, young pollock have not been found in the stomachs of adult JSS. Warm temperatures in the Sea of Japan seem to induce the separation of young and adult pollock, and the shape of the stock–recruitment relationship also suggests that cannibalism is not important for JSS. Based on this knowledge, and on the hatch date distributions of larvae and juveniles, we propose mechanisms that can explain the recruitment fluctuations for JPS and JSS pollock. 相似文献