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491.
492.
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1 总被引:1,自引:0,他引:1
Hacein-Bey-Abina S Von Kalle C Schmidt M McCormack MP Wulffraat N Leboulch P Lim A Osborne CS Pawliuk R Morillon E Sorensen R Forster A Fraser P Cohen JI de Saint Basile G Alexander I Wintergerst U Frebourg T Aurias A Stoppa-Lyonnet D Romana S Radford-Weiss I Gross F Valensi F Delabesse E Macintyre E Sigaux F Soulier J Leiva LE Wissler M Prinz C Rabbitts TH Le Deist F Fischer A Cavazzana-Calvo M 《Science (New York, N.Y.)》2003,302(5644):415-419
493.
Burrows DN Romano P Falcone A Kobayashi S Zhang B Moretti A O'brien PT Goad MR Campana S Page KL Angelini L Barthelmy S Beardmore AP Capalbi M Chincarini G Cummings J Cusumano G Fox D Giommi P Hill JE Kennea JA Krimm H Mangano V Marshall F Mészáros P Morris DC Nousek JA Osborne JP Pagani C Perri M Tagliaferri G Wells AA Woosley S Gehrels N 《Science (New York, N.Y.)》2005,309(5742):1833-1835
Gamma-ray burst (GRB) afterglows have provided important clues to the nature of these massive explosive events, providing direct information on the nearby environment and indirect information on the central engine that powers the burst. We report the discovery of two bright x-ray flares in GRB afterglows, including a giant flare comparable in total energy to the burst itself, each peaking minutes after the burst. These strong, rapid x-ray flares imply that the central engines of the bursts have long periods of activity, with strong internal shocks continuing for hundreds of seconds after the gamma-ray emission has ended. 相似文献
494.
Chloe F. Sato Jeff T. Wood Mellesa Schroder Damian R. Michael William S. Osborne Ken Green David B. Lindenmayer 《Landscape Ecology》2014,29(7):1225-1236
Subalpine ecosystems are centres of endemism that are important for biodiversity. However, these areas are under threat from the creation, expansion and continued modification of ski runs, activities that have largely negative effects on wildlife. Despite this threat, research on the impacts of ski runs is limited for reptiles—particularly regarding the value of remnant vegetation retained on ski runs. Here we quantify the effects of habitat loss and fragmentation (i.e., patch size, patch isolation and edge effects) on the abundance of a common subalpine lizard and on thermal regimes (a key determinant of lizard distribution) in an Australian ski resort. The number of lizards observed differed significantly with habitat type (ski runs vs. forested areas) and patch isolation, but not patch size. In addition, the edges of patches supported more lizards than any other habitat type. These patterns of lizard distribution can be explained, in part, by the differing thermal regimes in each habitat. Ski runs had significantly higher ground surface temperatures than any other habitat type, precluding their use for a considerable proportion of the activity period of a lizard. In comparison, edges were characterised by lower temperatures than ski runs, but higher temperatures than the core of forested areas, potentially providing a favourable environment for thermoregulation. Based on our results, we conclude that although modified ski runs have a negative effect on lizards, patches of remnant vegetation retained on ski runs are of value for reptiles and their conservation could help mitigate the negative effects of habitat loss caused by ski run creation. 相似文献
495.
A mutant form was found in an M(2) population of wheat Triticum aestivum L. em. Thell. (aestivum group) 'Seneca'. The population was derived from soaked grains treated with 3.2 kilorads of gamma rays. The first and second internodes below the spike were reduced in length 33 and 15 percent, respectively, and the total height was 18 percent shorter than the prototype. The flag leaf sheath was normal in length resulting in spike placement below the flag leaf lamina. Segregation data suggest that one dominant gene controls this character. The canopy structure of a population of mutant plants is different from that of the normal type; therefore, this mutant can be used to evaluate light interception and physiological aspects of crop productivity. 相似文献
496.
497.
A curve is constructed showing changes in sea level at the Santa Monica shelf over the past 18,000 years. The curve is based on radiocarbon dates, sedimentologic data, and high-resolution seismic stratigraphic analysis of late Quaternary terrace deposits. Sea level was 117 meters below its present position about 18,000 years ago. During the first 8000 years of the Flandrian transgression, sea level rose to at least 24 meters, fell to about 46 meters, and then rose to 20 meters, all below present sea level. Subsequently, sea level rose more slowly and without discernible interruption to its present position. 相似文献
498.
Compositional,functional and storage properties of flours from raw and heat processed African breadfruit (Treculia africana Decne) seeds 总被引:1,自引:0,他引:1
Giami SY Adindu MN Akusu MO Emelike JN 《Plant foods for human nutrition (Dordrecht, Netherlands)》2000,55(4):357-368
African breadfruit (Treculia africana Decne) seeds were either boiled or roasted and then milled into flour. Chemical composition, functional properties and storage characteristics of raw and treated flours and the effect of partial proteolysis on selected functional properties of the raw flour were determined. Raw flour contained 20.1% crude protein, 2.5% total ash and 13.7% fat. Heat processing significantly (p<0.05) improved in vitro protein digestibility, and water and fat absorption capacities but decreased bulk density, nitrogen solubility, emulsion and foaming properties, trypsin inhibitor, and phytic acid and polyphenol contents of the samples. Boiling proved more effective than roasting for improving protein digestibility, emulsion capacity and foam stability and reducing antinutritional factor levels. Partial proteolysis increased nitrogen solubility, bulk density and water and fat absorption capacities but decreased foam capacity at hydrolysis levels greater than 35%. Fatty acid and peroxide values of the samples increased during storage. Compared to raw samples, heat processed samples had significantly (p<0.05) lower and more acceptable peroxide values and free fatty acid contents and higher and more stable water (3.0 g/g sample) and fat (2.4 g/g sample) absorption capacities. 相似文献
499.
500.