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151.
152.
杨昊天 陈永平 王志强 黄宇翔 马志刚 邹跃 魏念冬 张红 李鑫 董佳强 吕明哲 李洪彬 刘力威 杨昊轩 张国华 刘雪松 钟鹏 石荷叶 寇玉红 陈志峰 《畜牧兽医学报》2023,54(2):779-786
本研究拟探索右美托咪定(dexmedetomidine,DEX)对大鼠急性应激致肾损伤的保护作用,并从氧化应激的角度探索DEX对大鼠肾的保护通路。本研究使用了急性束缚应激模型,其中,大鼠被迫游泳15 min,并束缚3 h。本试验采用生化检测、组织病理学切片观察以评估肾功能,然后测定了氧化应激以及氧化应激的相关通路蛋白。旷场试验证实成功建立了急性应激模型。急性应激引起的肾损伤增加了NOX4,降低了Nrf2/HO-1/NQO1表达水平。DEX可降低NOX4表达,同时升高Nrf2/HO-1/NQO1的表达水平。DEX治疗组与急性应激组相比的肾生化结果明显恢复正常,病理切片观察损伤显著降低。试验结果表明,DEX治疗急性应激可影响NOX4/Nrf2/HO-1/NQO1信号通路,并抑制氧化应激。因此,DEX对急性应激引起的肾损伤具有保护作用,并在应激综合征中具有潜在的临床应用。 相似文献
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本文论述了中西方文化对于管理的影响,分析了中国式管理出现的文化因素,总结了中国传统文化在现代管理中可加以运用的结合点,提出应该更有自信的看待我们自己管理方式的观点。 相似文献
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The inelastic dynamic response analysis program for frame-shear wall structures developed by the authors is introduced firstly, in which the multi-vertical-line-element model was adopted for shear walls and the refined single-component model was used for beams and columns in frame.By analyzing three-story structural models tested in shaking-table in a famous foreign research institute, the validity of the modeling of shear wall in the program was verified. The analytical results indicate that the inelastic dynamic responseof shear walls under random ground motion input can be predicted effectively withthe program. Finally, with the preliminary discussion of some key points in modeling of shear wall, some suggestions areput forward for further improving and refining the multi-vertical-line-element model. 相似文献
157.
Investment on construction projects has become an important factor in improving the development of economy in China.The non-price bottom bidding is a representation that the investment on projects is becoming standardized.During the years of trying out the non-price bottom bidding,the colluding in bidding or bidding below the cost has happened several times,which have damaged the benefits of owners.To solve theses problems,this paper firstly studies the reason of these problems-the failure in the normal relationship between principal and agent.Then,some measures have been presented as follows: building systematic and scientific system of qualification prejudication,judging behaviors of colluding in bidding and bidding below the cost with reason and providing a surety mechanism of the project.The authors hope that these measures are beneficial to non-price bottom bidding. 相似文献
158.
Mortgage-backed securities(MBS),originated in the U.S.and introduced into China in 2005,is a vehicle for real estate finance.This paper describes their history,mechanism,development,theory and experiences in the USA and other countries.In China,the real estate finance is partitioned into four stages: first,non-finance stage(1949-1977);second,sprouting stage(1978-1997);third,inceptive stage(1998-2004) and the fourth,developing stage(2005-),and it is distinguished from the finance of Real Estate Development firm.The differences between them are in following aspects: object,objective,mode and risk.This paper analyzes the institutional defects in view of the policy environment,the primary market of MBS,the secondary market of MBS,and offers countermeasures: first,setting up National Housing Mortgage Management Institution,second,enlarging the service scope of housing mortgage-backed loan,third,differential loaning,fourth,regularly issuing the pricing of housing construction;fifth,normalizing the institutional investors. 相似文献
159.
With the study of minbus's accelerated exterior noise control,the principle of sound intensity measurement was applied,the sound intensity of a minbus's surface noise was tested,and the surface noise distribution was presented.Several identification of noise source methods including sound power,sound intensity contour map,frequency spectrum were used together for surface noise analysis and study.Engine radiation noise and exhaust noise was identified as the major noise sources.On the contrary,car body vibration noise,tyre noise,transmission agent noise,air admission noise just occupied a little proportion of surface sound radiation energy.The research provides the reliable basis to determine main projects of minibus's accelerated exterior noise control. 相似文献
160.
According to the diffusion equation of carburizing process and its boundary conditionand initial condition, various shapes steel parts are modeled under various case carburize craft parameters, concentration distribution curves have been obtained. Various craft parameters are compared, and carburizing temperature has more influence on carbon concentration distribution. Various shapes steel parts' carbon concentration distribution curves have some difference. According to the carbon concentration distribution curve, craft parameters can be adjusted in order to obtain the best carburizing craft. 相似文献