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511.
Germana Esposito Roberta Teta Roberta Miceli Luca S. Ceccarelli Gerardo Della Sala Rosa Camerlingo Elena Irollo Alfonso Mangoni Giuseppe Pirozzi Valeria Costantino 《Marine drugs》2015,13(1):444-459
The study of the secondary metabolites contained in the organic extract of Caribbean sponge Smenospongia aurea led to the isolation of smenothiazole A (3) and B (4), hybrid peptide/polyketide compounds. Assays performed using four solid tumor cell lines showed that smenothiazoles exert a potent cytotoxic activity at nanomolar levels, with selectivity over ovarian cancer cells and a pro-apoptotic mechanism. 相似文献
512.
513.
Giuseppe Firrao Emanuela Torelli Emanuela Gobbi Steluta Raranciuc Gianluca Bianchi Romano Locci 《Journal of Cereal Science》2010
Mycotoxin contamination is a major concern to the maize industry worldwide. Despite the several strategies that have been exploited in an attempt to reduce the severity of this problem, during conducive years, severely contaminated lots are still introduced in the maize processing chain affecting the general quality and safety of the product. As chemical analysis is laborious, time consuming and equipment dependent, more convenient methods are needed for the early identification of contaminated lots. Here a novel approach based on image analysis that provides fast response with minimal equipment and effort is presented. Maize samples were grounded and imaged under 10 different LED lights with emission centered at wavelengths ranging from 720 to 940 nm. The digital images were converted into matrices of data to compute comparative indexes. A three layers feed-forward neural network was trained to predict mycotoxin content from the calculated indexes. The results showed a significant correlation between predictions from image analysis and the concentration of the mycotoxin fumonisin as determined by chemical analysis. The technique developed produces reliable contamination estimates within few minutes and can be readily used to assist lot selection in various steps of the maize processing chain. 相似文献
514.
Giuseppe Piccione Stefania Casella Claudia Giannetto Elisabetta Giudice 《Journal of veterinary science (Suw?n-si, Korea)》2010,11(2):121-124
The present study was to assess the effect of storage conditions on prothrombin time (PT), activated partial thromboplastin time (aPTT) and fibrinogen concentration in blood samples of healthy dogs. Thirty-five dogs of various breeds were included in the study. Citrated blood samples were obtained and plasma was divided into four aliquots to assess selected clotting parameters by means of a coagulometer. The first aliquot was analysed within 1 h after collection, while the remaining 3 were stored at 8℃ for 4, 8 and 24 h, respectively. One-way repeated measures analysis of variance documented a significant decreasing effect on PT at 24 h compared to 8 h and on fibrinogen concentration after 8 and 24 h compared to sampling time and at 4 and 24 h compared to 8 h post sampling. In conclusion, the results of this study indicate that only fibrinogen appears prone to significant decrease. In fact, aPTT is not substantially affected by refrigeration for at least 24 h post sampling and PT showed a statistical difference that does not necessary indicate biological significance as the results obtained were within reference intervals for the dog. 相似文献
515.
Massimo MORGANTE Matteo GIANESELLA Elisabetta VERSACE Laura CONTALBRIGO Stefania CASELLA Chiara CANNIZZO Giuseppe PICCIONE Calogero STELLETTA 《Animal Science Journal》2010,81(6):722-730
To evaluate the metabolic profile of pregnant and non‐pregnant ewes with high or low degree of behavioral lateralization, we used 57 clinically healthy Sardinian ewes. They were divided into three groups: Group A (nonpregnant ewes), Group B (pregnant ewes with one fetus) and Group C (pregnant ewes with twin fetuses). Using behavioral tests, in all groups lateralization was established and ewes were distinguished into ewes with high and low level of lateralization. Every 30 days for 4 months (at 35, 76, 103 and 145 days of gestation), blood samples were collected and total cholesterol, triglycerides, nonesterified fatty acids (NEFA), glucose, insulin, creatinine, urea, uric acid, total protein, total bilirubin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), γ‐glutamine transferase (γ‐GT), β‐hydroxybutyrate (β‐OHB), chloride (Cl), potassium (K), sodium (Na) and calcium (Ca) were assessed. The repeated measures multifactor analysis of variance (MANOVA) showed statistical differences of time, pregnancy and degree of lateralization on some studied parameters. These results confirm that pregnancy represents a very important metabolic moment and show the effect of the degree of behavioral lateralization on the assessment of metabolic parameters in non‐pregnant and pregnant ewes. Further studies are necessary to value the influence of these factors on other parameters such as hematological parameters and hormones. 相似文献
516.
Donald A. Croll Heidi Dewar Nicholas K. Dulvy Daniel Fernando Malcolm P. Francis Felipe Galván‐Magaña Martin Hall Shawn Heinrichs Andrea Marshall Douglas Mccauley Kelly M. Newton Giuseppe Notarbartolo‐Di‐Sciara Mary O'Malley John O'Sullivan Marloes Poortvliet Marlon Roman Guy Stevens Bernie R. Tershy William T. White 《水产资源保护:海洋与淡水生态系统》2016,26(3):562-575
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517.
Quintavalla C Bossolini E Rubini G Tursi M 《Journal of the American Animal Hospital Association》2010,46(6):444-448
A 2-year-old, neutered male, domestic shorthair cat was presented for investigation of dyspnea and episodic weakness. Clinical and ultrasonographic features were consistent with right ventricular cardiomyopathy. Pathological findings documented Uhl's anomaly. Although rare, Uhl's anomaly should be a differential diagnosis for cats with right-sided congestive heart failure. In particular, Uhl's anomaly could be misdiagnosed as arrhythmogenic right ventricular cardiomyopathy due to the similarity of clinical and echocardiographic findings. 相似文献
518.
José M. Vilar Gustavo Ramirez Giuseppe Spinella Alfonso Martinez 《The Canadian veterinary journal. La revue veterinaire canadienne》2010,51(3):289-292
A 6-year-old Doberman pinscher dog was presented with myositis ossificans of the semimembranosus muscle. Linear, temporal, and angular kinematic patterns were recorded and compared with those of sound dogs of the same breed. The results indicate that the specific gait compensations occurring with this disease may aid in the diagnosis of myositis ossificans of the caudal thigh muscles. 相似文献
519.
520.
Blood lipids, fecal fat and chymotrypsin excretion in the dog: influence of age, body weight and sex
Piccione G Fazio F Giudice E Grasso F Caola G 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2004,66(1):59-62
Effects of physiological variables (age, body weight and sex) on lipemia (total lipids, phospholipids, triglycerides and NEFA), fecal fat and chymotrypsin excretion were examined in dogs. On comparing various ages and body weights, they found statistically significant differences, while only total lipids showed a statistically significant difference between the two sexes. Moreover, there was a significant correlation between body weight and fecal fat and chymotrypsin excretion. The results obtained contribute to the evaluation of small intestine functionality, especially in relation to some diseases, as malabsorption, maldigestion and steatorrhea in the dog. 相似文献