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71.
The marine ecosystem, populated by a myriad of animals, plants, and microorganisms, is an inexhaustible reservoir of pharmacologically active molecules. Among the multiple secondary metabolites produced by marine sources, there are anthraquinones and their derivatives. Besides being mainly known to be produced by terrestrial species, even marine organisms and the uncountable kingdom of marine microorganisms biosynthesize anthraquinones. Anthraquinones possess many different biological activities, including a remarkable antitumor activity. However, due to their peculiar chemical structures, anthraquinones are often associated with toxicological issues, even relevant, such as genotoxicity and mutagenicity. The aim of this review is to critically describe the anticancer potential of anthraquinones derived from marine sources and their genotoxic and mutagenic potential. Marine-derived anthraquinones show a promising anticancer potential, although clinical studies are missing. Additionally, an in-depth investigation of their toxicological profile is needed before advocating anthraquinones as a therapeutic armamentarium in the oncological area. 相似文献
72.
Giulia Mattalia Cassandra L. Quave Andrea Pieroni 《Genetic Resources and Crop Evolution》2013,60(2):587-603
An ethnobotanical field study on the traditional uses of wild medicinal and food plants was conducted in three linguistically distinct mountainous communities located at the East End of the Occitan macro-area, in the Western Italian Alps. Interviews with a total of 81 mid-aged and elderly informants were undertaken using standard ethnobotanical methods. The uses of 92 vascular plants belonging to 40 different plant families were recorded. Comparison of the collected data with the ethnobotanical findings of previously conducted studies in other Occitan/Provençal valleys (specifically the Stura and Varaita valleys) has shown that nearly the half of the uses recorded in this study were not reported in other valleys, strongly suggesting a heterogeneous character to Occitan ethnobotany. The specific uses of certain wild plants as famine foods and medicines in this region are highlighted. 相似文献
73.
This study aimed to investigate the relationships between leaf functional modifications and heavy metal concentrations of Quercus ilex L., a good bioindicator of air quality. In addition, as metal concentration in litter plays an important role in decomposition and, in turn, in biogeochemical cycles, samples of undecomposed and whole‐leaf litter were analyzed for heavy metals. Leaves and leaf litter of Q. ilex were collected at six sites (roadsides, motorway sites, and urban parks) in Naples (Southern Italy) and characterized for Cd, Cr, Cu, Ni, and Pb concentrations. The investigated functional leaf traits were: leaf area (LA), specific leaf area (SLA), leaf dry‐matter content (LDMC), water content (WC), leaf relative water content (RWC), maximal PSII photochemical efficiency (Fv/Fm, variable fluorescence / maximal fluorescence), and total chlorophyll concentration. The motorways were the most contaminated sites, and Pb was the main responsible source of contamination. The metal contamination caused slight variation of Fv/Fm, suggesting that metals did not significantly alter functionality of the photosynthetic apparatus. On the other hand, it can be supposed that higher leaf deposit can cause an increase of pigment biosynthesis in response to the shading increase caused by dust deposition. 相似文献
74.
Francesco Cavraro Giada Finotti Giulia Rossato Matteo Zucchetta Chiara Facca Stefano Malavasi 《水产资源保护:海洋与淡水生态系统》2021,31(6):1311-1321
- In transitional water ecosystems, habitat loss is one of the major threats to fish biodiversity. This is particularly true in the case of temperate salt marshes. Good quality artificial novel habitats may compensate for the loss of natural habitats, acting as a refuge for fish populations.
- The aim of this study was to use coloured ornamental traits exhibited by the males of a small lagoon-resident fish, the Mediterranean killifish Aphanius fasciatus (Valenciennes, 1821), to assess habitat quality in both the natural and artificial creeks of the Venice lagoon.
- The conspicuousness of two secondary sexual traits, the yellow/orange caudal fin pigmentation and the contrast between white and dark vertical bars on body sides, proved to be greater in artificial habitats compared to natural salt marshes, highlighting the refuge function of artificial creeks.
- The use of secondary sexual traits could be extended to other fish species and to other aquatic habitats as a non-invasive approach. This would allow the identification of good quality habitats in the context of fish population management and conservation.
75.
Pavela Roman Pavoni Lucia Bonacucina Giulia Cespi Marco Cappellacci Loredana Petrelli Riccardo Spinozzi Eleonora Aguzzi Cristina Zeppa Laura Ubaldi Massimo Desneux Nicolas Canale Angelo Maggi Filippo Benelli Giovanni 《Journal of pest science》2021,94(3):899-915
Journal of Pest Science - Carlina acaulis root essential oil (EO) is one of the most potent mosquito larvicides (LC50?<?2 ppm). This EO is mainly composed of carlina... 相似文献
76.
Eleonora Binatti Gianni Zoccatelli Francesca Zanoni Giulia Don Federica Mainente Roberto Chignola 《Marine drugs》2021,19(3)
Radiation-induced fibrosis is a serious long-lasting side effect of radiation therapy. Central to this condition is the role of macrophages that, activated by radiation-induced reactive oxygen species and tissue cell damage, produce pro-inflammatory cytokines, such as transforming growth factor beta (TGF). This, in turn, recruits fibroblasts at the site of the lesion that initiates fibrosis. We investigated whether astaxanthin, an antioxidant molecule extracted from marine and freshwater organisms, could help control macrophage activation. To this purpose, we encapsulated food-grade astaxanthin from Haematococcus pluvialis into micrometer-sized whey protein particles to specifically target macrophages that can uptake material within this size range by phagocytosis. The data show that astaxanthin-loaded microparticles are resistant to radiation, are well-tolerated by J774A.1 macrophages, induce in these cells a significant reduction of intracellular reactive oxygen species and inhibit the release of active TGF as evaluated in a bioassay with transformed MFB-F11 fibroblasts. Micro-encapsulation of bioactive molecules is a promising strategy to specifically target phagocytic cells and modulate their own functions. 相似文献
77.
Stiaccini G Mannari C Bertelli AA Giovannini L 《Plant foods for human nutrition (Dordrecht, Netherlands)》2012,67(3):289-293
The cardioprotective and anti-aging effects of red wine phenols, especially resveratrol (RSV), are well known. One of the most interesting biological properties of RSV and other naturally occurring phenols is the regulation of the expression and activity of SIRT1 (silent mating type information regulation 2 homolog). In view of the role of SIRT1 in acute and chronic renal diseases, we decided to study the effects of RSV-poor red wines on the expression of SIRT1 and HIF-2α (hypoxia-inducible factor 2α) to be compared with a nanomolar concentration of RSV or malvidin in proximal tubular cells of human kidneys (PTEC). Survival signaling systems activation (extracellular signal-regulated kinases, ERK and AMP-activated protein kinase, AMPK) was also investigated in PTEC incubated with wines. PTEC cells were incubated in the presence of RSV-poor wines diluted 1:1,000 for 30', 90', 120' and 24?h. Expression of SIRT1 and HIF-2α, and activation of ERK and AMPK were analyzed by Western Blot. The data obtained show that wine modulates the expression of anti-aging molecular systems even when RSV is present in very small amounts. 相似文献
78.
Experimental rearing of the sea urchin Paracentrotus lividus fed with discards of the lettuce Lactuca sativa in a sea‐based system 下载免费PDF全文
Salvatrice Vizzini Giulia Visconti Antonino Vaccaro Antonio Mazzola 《Aquaculture Research》2018,49(2):631-636
Small‐sized specimens (test diameter: 16.64 ± 0.93 mm, mean ± SE) of the sea urchin Paracentrotus lividus were fed with fresh discards of the lettuce Lactuca sativa during a 24‐week experiment in a sea‐based system. At the end of the experiment, stock survival was high (88.8 ± 6.6%). Sea urchin test diameter and total weight grew by 35% and 56%, respectively, while gonad somatic index, after an initial decrease, increased by 3.2%. Moreover, more than 90% of specimens achieved the gonad colour that the market demands. These results support the exploitation of L. sativa as the main ingredient in a manufactured diet for echinoculture of P. lividus. Employing diets formulated with discard ingredients, combined with a low‐cost sea‐based rearing system, could be a suitable approach for sustainable management of echinoculture. 相似文献
79.
Ferracane R Pellegrini N Visconti A Graziani G Chiavaro E Miglio C Fogliano V 《Journal of agricultural and food chemistry》2008,56(18):8601-8608
In this study, the effects of three common cooking practices (i.e., boiling, steaming, and frying) on the artichoke phenolic compounds pattern were evaluated by LC-MS/MS analysis. The variation of carotenoids, antioxidant capacity, and artichoke physical properties after cooking was also investigated. The major phenolic compounds present in the raw sample were 5- O-caffeoylquinic and 1,5-di- O-caffeoylquinic acids; after cooking treatments, an increase of the overall caffeoylquinic acids concentration due to the formation of different dicaffeoylquinic acid isomers was observed. Steamed and fried samples showed similar patterns of dicaffeoylquinic concentrations, which were higher with respect to the boiled samples. On the other hand, all cooking practices, particularly frying, decreased flavonoid concentration. The antioxidant capacity of cooked artichokes, measured by three different assays, enormously increased after cooking, particularly after steaming (up to 15-fold) and boiling (up to 8-fold). The observed cooking effect on the artichoke antioxidant profile is probably due to matrix softening and increased extractability of compounds, but the increase of antioxidant capacity is much higher than the increase of antioxidant concentration. These results suggest that some common cooking treatments can be used to enhance the nutritional value of vegetables, increasing bioaccessibility of health-promoting constituents. 相似文献