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431.
Ceccarelli Viviana Lastra Sphyros Loor Solrzano Rey Gastn Chacn Walter Wenceslao Nolasco Mario Sotomayor Cantos Ignacio Antonio Plaza Avelln Luis Fernando Lpez Diana Aracelly Fernndez Anchundia Fabian Marcelo Dessauw Dominique Orozco-Aguilar Luis Thomas Evert 《Genetic Resources and Crop Evolution》2022,69(3):1283-1302
Genetic Resources and Crop Evolution - Cacao (Theobroma cacao L.) is among the most important cash crops in tropical countries. The existing cacao genetic diversity represents a key resource to... 相似文献
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Zoriţa Diaconeasa Huseyin Ayvaz Dumitriţa Ruginǎ Loredana Leopold Andreea Stǎnilǎ Carmen Socaciu Flaviu Tăbăran Lavinia Luput Diana Carla Mada Adela Pintea Andrew Jefferson 《Plant foods for human nutrition (Dordrecht, Netherlands)》2017,72(4):404-410
Anthocyanins are water soluble pigments which have been proved to exhibit health benefits. Several studies have investigated their effects on several types of cancer, but little attention has been given to melanoma. The phytochemical content of nine different berry samples was assessed by liquid chromatography followed by electrospray ionization mass spectrometry (LC-ESI+-MS). Twenty-six anthocyanins were identified, after a previous C18 Sep-pak clean-up procedure. Chokeberry and red grape anthocyanins rich extracts (C-ARE and RG-ARE) were selected to be tested on normal and melanoma cell lines, due to their different chemical pattern. C-ARE composition consists of cyanidin aglycone glycosylated with different sugars; while RG-ARE contains glucosylated derivatives of five different aglycones. Both C-ARE and RG-ARE anthocyanins reduced proliferation, increased oxidative stress biomarkers and diminished mitochondrial membrane potential in melanoma cells, having no negative influence on normal cells. A synergistic response may be attributed to the five different aglycones present in RG-ARE, which proved to exert greater effects on melanoma cells than the mixture of cyanidin derivatives with different sugars (C-ARE). In conclusion, C-ARE and RG-ARE anthocyanins may inhibit melanoma cell proliferation and increase the level of oxidative stress, with opposite effect on normal cells. Therefore, anthocyanins might be recommended as active ingredients for cosmetic and nutraceutical industry. 相似文献
434.
Ian D. Hogg S. Craig Cary Kevin K. Newsham Byron J. Adams Francesco Frati Diana H. Wall 《Soil biology & biochemistry》2006,38(10):3035-3040
Antarctic terrestrial ecosystems are noted for their relative simplicity and limited trophic structure. In this context, knowledge of biotic interactions in structuring terrestrial soil communities would seem beneficial from a theoretical perspective as well as from a conservation perspective. Unfortunately, although biotic interactions are generally seen as being insignificant in these unique ecosystems, this view is based upon few explicit studies and very little is known of the role that biotic interactions may play. Accordingly, we review our current understanding of these interactions, including analogues from other appropriate ecosystems. On the basis of this review, we conclude that: (1) Antarctic terrestrial systems are predominantly abiotically-driven systems; and (2) a network of manipulative field and laboratory experiments are needed for establishing any role for biotic interactions in structuring Antarctic soil environments. 相似文献
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Gorelick-Feldman J Maclean D Ilic N Poulev A Lila MA Cheng D Raskin I 《Journal of agricultural and food chemistry》2008,56(10):3532-3537
Phytoecdysteroids, which are structurally similar or identical to insect molting hormones, produce a range of effects in mammals, including increasing growth and physical performance. To study the mechanism of action of phytoecdysteroids in mammalian tissue, an in vitro cellular assay of protein synthesis was developed. In C2C12 murine myotubes and human primary myotubes, phytoecdysteroids increased protein synthesis by up to 20%. In vivo, ecdysteroids increased rat grip strength. Ecdysteroid-containing plant extracts produced similar results. The effect was inhibited by a phosphoinositide kinase-3 inhibitor, which suggests a PI3K-mediated mechanism. 相似文献
437.
Fertilization is the sum of the cellular mechanisms that pass the genome from one generation to the next and initiate development of a new organism. A typical, ovulated mammalian egg is enclosed by two layers: an outer layer of approximately 5000 cumulus cells and an inner, thick extracellular matrix, the zona pellucida. To reach the egg plasma membrane, sperm must penetrate both layers in steps requiring sperm motility, sperm surface enzymes, and probably sperm-secreted enzymes. Sperm also bind transiently to the egg zona pellucida and the egg plasma membrane and then fuse. Signaling in the sperm is induced by sperm adhesion to the zona pellucida, and signaling in the egg by gamete fusion. The gamete molecules and molecular interactions with essential roles in these events are gradually being discovered. 相似文献
438.
A MADS-box gene necessary for fruit ripening at the tomato ripening-inhibitor (rin) locus 总被引:2,自引:0,他引:2
Vrebalov J Ruezinsky D Padmanabhan V White R Medrano D Drake R Schuch W Giovannoni J 《Science (New York, N.Y.)》2002,296(5566):343-346
Tomato plants harboring the ripening-inhibitor (rin) mutation yield fruits that fail to ripen. Additionally, rin plants display enlarged sepals and loss of inflorescence determinacy. Positional cloning of the rin locus revealed two tandem MADS-box genes (LeMADS-RIN and LeMADS-MC), whose expression patterns suggested roles in fruit ripening and sepal development, respectively. The rin mutation alters expression of both genes. Gene repression and mutant complementation demonstrate that LeMADS-RIN regulates ripening, whereas LeMADS-MC affects sepal development and inflorescence determinacy. LeMADS-RIN demonstrates an agriculturally important function of plant MADS-box genes and provides molecular insight into nonhormonal (developmental) regulation of ripening. 相似文献
439.
Recent research in cognitive and developmental neuroscience is providing a new approach to the understanding of dyscalculia that emphasizes a core deficit in understanding sets and their numerosities, which is fundamental to all aspects of elementary school mathematics. The neural bases of numerosity processing have been investigated in structural and functional neuroimaging studies of adults and children, and neural markers of its impairment in dyscalculia have been identified. New interventions to strengthen numerosity processing, including adaptive software, promise effective evidence-based education for dyscalculic learners. 相似文献