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971.
972.
Sera collected from the southern parts of Japan were subjected to serological tests for antibodies to 24 arthropod-borne or suspected arthropod-borne viruses. A high incidence (82%) of hemagglutination-inhibiting (HI) antibodies was found with Japanese encephalitis (JE) virus. HI antibodies to other Flaviviruses, Murray Valley encephalitis, Apoi, Kunjin, Stratford and Kokobera, were also found in some of the sera, but seemed to be due to cross reaction with JE virus. High neutralizing (NT) antibody incidences were obtained with Akabane (60%) and Aino (30%) viruses known to be endemic in Japan. NT antibodies were also found for Bunyaviruses, Batai and Wongla; Reoviridae viruses, D'Aguilar, Warrego, and Mitchell River; and Kowanyama and Belmont viruses. Complement fixing antibodies were found for Reoviridae viruses bluetongue type 1 and Ibaraki; Picornavirus Nodamura and Rhabdovirus bovine ephemeral fever. No antibodies were detected with Reoviridae viruses Corriparta and Eubenangee; Bunyavirus Trubanaman; and Alfavirus Chikungunya. 相似文献
973.
E. Takahashi Y. Inaba K. Sato Y. Ito H. Kurogi H. Akashi K. Satoda T. Omori 《Veterinary microbiology》1980,5(2):151-154
An epizootic of acute diarrhoea of adult cattle occured in Japan during the winter of 1976 to 1977. A majority of adult cattle clinically diagnosed as having the disease, showed a significant rises in antibody titres to bovine coronavirus, whereas only a smal; minority showed serological evidence of recent infection with calf rotavirus, bovine adenovirus type 7, parainfluenza virus type 3, or bovine viral diarrhoea-mucosal disease virus. A coronavirus-like agent was detected by electron-microscopy in faecal material from a cow with diarrhoea, and was subsequently isolated in primary bovine kidney cell cultures. 相似文献
974.
975.
976.
Tepraloxydim [(EZ)‐(RS)‐2‐{1‐[(2E)‐3‐chloroallyloxyimino]propyl}‐3‐hydroxy‐5‐perhydropyran‐4‐ylcyclohex‐2‐en‐1‐one] showed high activity against annual bluegrass (Poa annua L.), which is relatively tolerant to sethoxydim [(±)‐2‐(1‐ethoxyiminobutyl)‐5‐[2‐(ethylthio)propyl]‐3‐hydroxycyclohex‐2‐en‐1‐one]. Absorption and translocation rates of tepraloxydim and sethoxydim were higher in P. annua than in Setaria faberi, but the absorption and translocation patterns of tepraloxydim in the two plants were similar to those of sethoxydim. Metabolic rates of tepraloxydim and sethoxydim in P. annua and S. faberi were found to be similar. The concentration for 50% inhibition (I50) of acetyl‐coenzyme A carboxylase (ACCase) with tepraloxydim was approximately 3 × 10?6 mol L?1 for P. annua and 7 × 10?7 mol L?1 for S. faberi. For sethoxydim, the I50 was found to be 2 × 10?6 mol L?1 with the enzyme of S. faberi, while sethoxydim showed a slight effect on ACCase from P. annua activity, even at 10?4 mol L?1. The strong inhibition of ACCase with tepraloxydim is considered to be the major factor contributing to the high herbicidal activity against P. annua. Measuring the whole plant growth response, the ratio of the tepraloxydim I50 dose of P. annua to that of S. faberi (P/S) was found to be 2.4, while the P/S ratio of sethoxydim and a tepraloxydim analog with a propyl chain at R2 were 56.3 and 73.3, respectively. The herbicidal activity against P. annua was remarkably influenced by the length of the R2 alkyl chain, while the effect on S. faberi was not affected. Acetyl‐coenzyme A carboxylase from P. annua also exhibited a higher resistance to the tepraloxydim analog with a propyl chain than to tepraloxydim. These results suggest that a binding site structure of cyclohexane‐1,3‐diones in the ACCase differs between P. annua and S. faberi. 相似文献
977.
Bla Darvas Huw H. Rees Nigel Hoggard Mahmoud H. Tag El-Din Eiichi Kuwano Ivn Blai Tibor Timr 《Pest management science》1992,36(2):135-142
The cytochrome P-450-dependent microsomal and mitochondrial ecdysone 20-monooxygenase systems convert ecdysone into 20-hydroxyecdysone. The microsomal fraction of fat bodies of zero h wandering stage fleshfly larvae (Neobellieria bullata; Diptera: Sarcophagidae) has a high ecdysone 20- monooxygenase activity. The effects of cytochrome P-450 inhibitors were investigated in vitro on microsomal ecdysone 20-monooxygenase. Metyrapone, fenarimol and certain imidazole derivatives (KK-42, KK-110, KK-135 and PIM) are strong inhibitors. The IC50 value of KK-110, which is the strongest inhibitor, is 2 × 10?7 M. A triazolyl and two cyclopropylamine derivatives have low activity. The activities of different NADPH-cytochrome c (P-450) reductase inhibitors were also assessed; diquat dibromide is a moderate inhibitor of microsomal ecdysone 20-monooxygenase, while paraquat dichloride has no activity. In-vivo experiments with cytochrome P-450 inducers and inhibitors gave the following results: (a) fenarimol, FI-121, precocene-2 caused “permanent” first-instar larvae; (b) barbital, phenobarbital and their sodium salts caused significant delay in larval development; (c) PIM, PTM, metyrapone, KK-42, KK-135, J-2710, RH 5849 and colchicine caused moulting disturbances; (d) J-2710, PIM, PTM, KK-42, KK-135, RH 5849 and colchicine caused lethal spiracle and mandible malformation; (e) KK-110, fenarimol, barbital and phenobarbital caused precocious pupariation. 相似文献
978.
1. Persistent hypoglycaemia was experimentally induced by insulin infusion to improve understanding of the regulatory mechanisms of blood glucose concentrations specific to chickens. 2. An osmotic minipump containing bovine insulin was implanted to deliver insulin in vivo at a constant rate (11.25 to 45 U/kg BW/d) for 5 d in 4-week-old broiler chickens force-fed a maintenance diet once a d. Birds infused with the highest dose of insulin died within 3 to 4 d. 3. In chickens continuously infused with insulin at 22.5 U/kg BW/d, fasting glucose concentrations in plasma determined every 3 h during the 3rd day of infusion were consistently and significantly lower than in controls. 4. Continuous infusion of insulin at 22.5 U/kg BW/d induced persistent hypoglycaemia (almost one-half the normal blood glucose concentration) lasting for at least 4 d in broiler chickens. 5. Insulin infusion did not significantly change plasma NEFA or protein concentrations and increased plasma GOT activity only at 1 of the daily experimental sampling points. 相似文献
979.
Inokuma H Mukai M Ohno K Yamamoto Y Takahashi S Onishi T 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》1999,61(2):179-181
A 24 kd protein from Rhipicephalus sanguineus (Rs24p) which was common to larvae, nymphs, male and female whole body and salivary gland extract of males and female was detected specifically in the serum from dogs after repeated infestation with adult R. sanguineus. The duration of antibodies against Rs24p in dogs infested with adults was examined by Western blotting analysis. Anti-Rs24p antibody was detected in two of 4 dogs during the period of 40 days in the first infestation. In the second infestation, all dogs showed positive reaction against Rs24p, but the duration of the antibodies varied greatly among the animals. 相似文献
980.