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排序方式: 共有4133条查询结果,搜索用时 359 毫秒
261.
Erlandson JM Rick TC Braje TJ Casperson M Culleton B Fulfrost B Garcia T Guthrie DA Jew N Kennett DJ Moss ML Reeder L Skinner C Watts J Willis L 《Science (New York, N.Y.)》2011,331(6021):1181-1185
Three archaeological sites on California's Channel Islands show that Paleoindians relied heavily on marine resources. The Paleocoastal sites, dated between ~12,200 and 11,200 years ago, contain numerous stemmed projectile points and crescents associated with a variety of marine and aquatic faunal remains. At site CA-SRI-512 on Santa Rosa Island, Paleocoastal peoples used such tools to capture geese, cormorants, and other birds, along with marine mammals and finfish. At Cardwell Bluffs on San Miguel Island, Paleocoastal peoples collected local chert cobbles, worked them into bifaces and projectile points, and discarded thousands of marine shells. With bifacial technologies similar to those seen in Western Pluvial Lakes Tradition assemblages of western North America, the sites provide evidence for seafaring and island colonization by Paleoindians with a diversified maritime economy. 相似文献
262.
Creutzfeldt-Jakob disease (spongiform encephalopathy): transmission to the chimpanzee 总被引:48,自引:0,他引:48
C J Gibbs D C Gajdusek D M Asher M P Alpers E Beck P M Daniel W B Matthews 《Science (New York, N.Y.)》1968,161(839):388-389
Biopsy material taken from the brain of a patient with CreutzfeldtJakob disease with status spongiosus induced a similar fatal encephalopathy in a chimpanzee 13 months after inoculation. 相似文献
263.
Against the neoliberal steamroller? The Biosafety Protocol and the social regulation of agricultural biotechnologies 总被引:1,自引:0,他引:1
Through a discursive and organizational analysis we seek to understand the Biosafety Protocol and the place of socioeconomic
regulation of agricultural biotechnology in it. The literature on the Protocol has been fairly extensive, but little of it
has explored debates over socioeconomic regulation during the negotiation process or the regulatory requirements specified
in the final document. This case is especially important at a time when the spread of neoliberalism is increasingly associated
with deregulation, because it sheds light on the conditions under which circumvention of the market is deemed legitimate and
socio-economic regulation of agricultural technology is possible.
Daniel Lee Kleinman
is a professor in the Department of Rural Sociology at the University of Wisconsin, Madison, where he is also affiliated
with the Holtz Center for Science and Technology Studies and the Integrated Liberal Studies Program. He is the author and
editor of a number of books, including Impure Cultures: University Biology and the World of Commerce (2003).
Abby J. Kinchy
is a PhD candidate in the Departments of Sociology and Rural Sociology at the University of Wisconsin, Madison. Her current
research examines the controversies surrounding the genetic “contamination” of Mexican maize and Canadian canola. 相似文献
264.
265.
The charge transport mechanism of a wire can be revealed by how its electrical resistance varies with length. We have measured the resistance and current-voltage characteristics of conjugated molecular wires ranging in length from 1 to 7 nanometers, connected between metal electrodes. We observe the theoretically predicted change in direct-current transport from tunneling to hopping as a function of systematically controlled wire length. We also demonstrate that site-specific disruption of conjugation in the wires greatly increases resistance in the hopping regime but has only a small effect in the tunneling regime. These nanoscale transport measurements elucidate the role of molecular length and bond architecture on molecular conductivity and open opportunities for greater understanding of electrical transport in conjugated polymer films. 相似文献
266.
267.
We have determined the 2.6 angstrom crystal structure of the entire extracellular region of human HER3 (ErbB3), a member of the epidermal growth factor receptor (EGFR) family. The structure consists of four domains with structural homology to domains found in the type I insulin-like growth factor receptor. The HER3 structure reveals a contact between domains II and IV that constrains the relative orientations of ligand-binding domains and provides a structural basis for understanding both multiple-affinity forms of EGFRs and conformational changes induced in the receptor by ligand binding during signaling. These results also suggest new therapeutic approaches to modulating the behavior of members of the EGFR family. 相似文献
268.
White fat progenitor cells reside in the adipose vasculature 总被引:1,自引:0,他引:1
Tang W Zeve D Suh JM Bosnakovski D Kyba M Hammer RE Tallquist MD Graff JM 《Science (New York, N.Y.)》2008,322(5901):583-586
White adipose (fat) tissues regulate metabolism, reproduction, and life span. Adipocytes form throughout life, with the most marked expansion of the lineage occurring during the postnatal period. Adipocytes develop in coordination with the vasculature, but the identity and location of white adipocyte progenitor cells in vivo are unknown. We used genetically marked mice to isolate proliferating and renewing adipogenic progenitors. We found that most adipocytes descend from a pool of these proliferating progenitors that are already committed, either prenatally or early in postnatal life. These progenitors reside in the mural cell compartment of the adipose vasculature, but not in the vasculature of other tissues. Thus, the adipose vasculature appears to function as a progenitor niche and may provide signals for adipocyte development. 相似文献
269.
270.
Bain DJ Smith SM Nagle GN 《Science (New York, N.Y.)》2008,321(5891):910; author reply 910-910; author reply 912