Etiology of the stomatitis pneumoenteritis complex in Nigerian dwarf goats.

The causative agent of stomatitis pneumoenteritis complex was isolated in domesticated goats and Vero cell culture. It was identified immunologically and morphologically as identical with the "Peste des Petits Ruminants" virus. There were cross reactions between stomatitis pneumoenteritis complex virus isolate and rinderpest virus by immunodiffusion and complement fixation tests but no cross neutralization. Goats recovered from stomatitis pneumoenteritis complex were protected against a challenge with rinderpest virus that was lethal to control goats. Ultrastructural morphology revealed intracytoplasmic and intranuclear inclusions made up of random arrays of fibrillar strands. Pleomorphic particles budded from the plasma membrane of infected cells and enveloped virions were seen extracellularly. Specific ferritin tagging was demonstrated in the stomatitis pneumoenteritis complex virus infected cells treated with homologous and peste des petits ruminants viral antibody systems but little, if any, tagging in the heterologous rinderpest system.     

Effect of noise on the physiological functions in fowl. 2. Adaptation to noise of white leghorns and broilers]

Two experimental groups and series were compared (leghorns and broilers as well as two age groups of broilers) for their adaptive responses to repeated noise application. The noise was 100 dB and applied daily 30 minutes. The reference for comparison was the plasma-11-hydroxycorticosteroid concentration (11-OHKS). The results differed somewhat from those obtained earlier from one first short-time noise application, in that the rise in plasma glucocorticosteroid concentrations dropped from 431 to 210 per cent of the initial values in adult leghorns exposed to repeated noise stress over seven days. Adult broilers, however, did not exhibit any difference in the magnitude of rise of 11-OHKS concentrations by comparison between first and seven days of repeated stress. The initial values, however, were reached earlier by repeated noise application.     

Structure-activity relationships of 1,2,3-benzothiadiazoles as synergists for carbaryl against the house fly (Musca domestica)

Fifty six 1,2,3-benzothiadiazoles and related compounds were evaluated as carbaryl synergists against the house fly (Musca domestica). Many of these were excellent synergists, the most active being those containing various combinations of halogen, alkyl, or alkoxy substituents in the 5- and/or 6-positions of the ring.Regression analysis on the data from 14 compounds for which substituents constants were available established that synergistic activity can be satisfactorily described by equations in terms of the hydrophobic bonding constant (π) and the homolytic free radical constant (σ ·).The results with compounds related to the 1,2,3-benzothiadiazoles suggest that synergistic activity is associated primarily with the diazosulfide moiety.     

A novel approach to Striga and Orobanche control using synthetic germination stimulants

A series of synthetic germination stimulants for the plant parasites Striga and Orobanche has been prepared. These compounds, analogues of the natural Striga germination stimulant, strigol (I), (Cook et al., 1966, 1972) cause signiticant germination of Striga hermonthica (Del.) Benth. seed at concentrations as low as 10^?9 M, and an even greater activity against species of Orobanche has been demonstrated. Initial outdoor box trials of the compounds against Striga asiatica (L.) O. Ktze. in Hyderabad, India, have shown a reduction of up to 65% of the seed after a single treatment of the soil 6 weeks before the planting of the sorghum host.     

The effects of progesterone on oviposition and ovulation in the domestic fowl (Gallus domesticus)

1. Following an injection of 0.5 or 0.1 mg progesterone/kg between 0 and 6 h after ovulation, oviposition of the resulting egg was delayed by 1 to 11 h and occurred 26 to 31 h after injection, depending on the dose. The injection terminated the laying of a sequence of eggs by causing the next ovulation to occur a day late. The delayed ovulation occurred at the time normally expected for the first ovulation of a sequence and became the first of a new sequence.

2. Following an injection of 0.5 or (H mg progesterone/kg between 6 and 15 h after ovulation, oviposition of the resulting egg was generally delayed by between 15 and 28 h and occurred at the same time of day as the next ovulation, which was delayed as in the first experimental situation. Subsequent ovulations were resynchronised and followed at intervals according to the normal sequence established before the injection.

3. Injection of 0.5, 0.1 or 0.05 mg progesterone/kg between 12 and 9 h before an expected ovulation advanced the oviposition of the egg already in the uterus (shell gland) by about 3 h. The succeeding ovulation was either advanced or blocked.

4. These observations suggest that the pre‐ovulatory surge of progesterone is directly or indirectly involved in the timing of oviposition and ovulation.     

The hen's egg: Shell cracking at impact on a heavy,stiff body and factors that affect it

1. Eggs from hens of three strains were dropped on to a heavy, stiff, smooth, plane body with impact at the equator of the shell; the height of drop, h_c, just sufficient to produce shell failure was measured and the corresponding impact velocity, v_c, calculated.

2. A small but commercially important percentage of the well‐formed eggs of one strain cracked when h_c was as low as 3–3 mm and v_c 250 mm/s.

3. Characteristics of the egg found to affect h_c and v_c included the overall thickness of its shell, thickness of its weak inner shell layer and average shell curvature, all measured at the point of impact, and its weight; its age also had a small effect (additional to that mediated through loss of weight); so did the degree of shell ridging.

4. No effect of shell colour was found.

5. Shell damage was typically a single hair‐crack that ran either round the equator or towards a pole.     

Agammaglobulinemia in a horse with evidence of functional T lymphocytes.

Agammaglobulinemia was diagnosed in a 1-year-old Thoroughbred horse on the basis of the following observations: (1) absence of serum immunoglobulins M, A, and G(T); (2) small amounts of serum immunoglobulin G (16 mg/100 ml); (3) absence of specific antibody in the serum of the horse following immunization and challenge exposure to 2 antigens; (4) absence of plasma cells, primary follicles, and germinal centers in a lymph node removed after antigenic stimulation; (5) absence of "natural" serum antibodies to rabbit-erythrocytes which were easily detectable in age-matched control horse serums; and (6) increased susceptibility to infections. There was evidence of functional cell-mediated immunity which included a skin response to injected phytolectins, skin response to antigen challenge following sensitization, and in vitro proliferative response of lymph node cells to phytohemagglutinin. An intact cell-mediated immune response was also supported by the observation that the horse lived to 17 months of age without antibody production, whereas horses with an absence of both antibody production and cell-mediated immunity (combined immunodeficiency) die by 4 months of age without immunologic intervention. The known features of agammaglobulinemia in this horse are similar to those in sex-linked agammaglobulinemia in persons and are unique among the immunodeficiences described in other animals.     

The effect of the administration of Solanum malacoxylon on the chick.

Replacement of the drinking water of chicks maintained on a normal mixed protein diet with an aqueous extract containing the equivalent of 5 g of the dried leaves of Solanum malacoxylon (DLSM) per 100 ml for one month produces a hypercalcaemia (23-49 per cent), hypomagnesamia (28-37 per cent), hypophosphataemia (26-34 per cent), hypouricaemia (29-34 per cent) and a decrease in plasma alkaline phosphatase activity (54-98 per cent). The ash content of the defatted, dried tibiae and the body weight of the DLSM treated chicks were also significantly lower (37-7 per cent and 17-79 per cent respectively) than the corresponding values for the untreated birds. The results obtained are similar to those reported for hypervitaminosis D3 in the chick.