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131.
132.
Mohammed Y. Khdiar Treena I. Burgess Paul A. Barber Giles E. St.J. Hardy 《Plant pathology》2023,72(1):112-119
Species in the genus Phytophthora cause significant economic losses in crops and damage to forests and natural ecosystems worldwide. Currently, phosphite is the most effective chemical for disease management, but excessive phosphite concentrations can result in phytotoxicity in plants and the development of tolerance by the pathogen. Two newly developed metal chelates and phosphite (alone and in combination) were tested for their in vitro and in planta efficacy against Phytophthora cinnamomi. In glasshouse trials, 0.25% and 0.5% of each chemical treatment (phosphite, Ca chelate, Zn chelate) and Ca chelate + phosphite were used as a foliar application on 3-month-old seedlings of Banksia grandis (experiment not repeated) and Eucalyptus marginata, prior to inoculation with P. cinnamomi. All noninoculated control plants remained healthy, while significant root damage and reduction of dry root weights were observed for inoculated untreated plants. Individually, phosphite and Ca chelate significantly reduced root lesion development of P. cinnamomi compared to the control, with Ca chelate attaining superior results to phosphite at the same concentration. In combination, Ca chelate + phosphite had the largest reduction in root lesion development in both plant species; however, this result has not yet been replicated but did reflect previous in vitro results. The Zn chelate applications were not effective. Ca chelate has the potential to be developed as a fungicide to control Phytophthora species. 相似文献
133.
Shem T. Oliver Joanne Hardy 《The Canadian veterinary journal. La revue veterinaire canadienne》2015,56(4):382-386
This study investigated 15 horses diagnosed with temporohyoid osteoarthopathy (THO) and treated by ceratohyoidectomy between 2004 and 2012. The presenting complaint, duration and nature of the clinical signs, additional diagnostic procedures, and complications were reviewed retrospectively. Long-term follow-up on horses was used to determine prognosis. All horses were diagnosed by guttural pouch endoscopy. Follow-up was available for 14 horses that survived to discharge. Eight of 10 horses that were used athletically prior to surgery returned to previous levels of use. Persisting clinical signs included mild facial nerve paralysis (3/14; 21.4%) or head tilt (6/14; 42.8%) but these were not functionally limiting. It was concluded that equine THO affects a wide range of breeds, disciplines, and ages of horses, and has a variety of presenting clinical signs most commonly associated with vestibular and facial nerves. Prognosis following ceratohyoidectomy is good for resolution of ataxia but some cranial nerve deficits may persist. 相似文献
134.
Treatment of Ionized Hypercalcemia in 12 Cats (2006–2008) Using PO‐Administered Alendronate
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B.T. Hardy J.F. de Brito Galvao T.A. Green S.R. Braudaway S.P. DiBartola L. Lord D.J. Chew 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2015,29(1):200-206
Background
Long‐term treatment of cats with ionized hypercalcemia using alendronate has not been evaluated.Hypothesis/Objectives
Alendronate is well tolerated in treatment of ionized hypercalcemia in cats.Animals
A total of 12 cats with ionized hypercalcemia.Methods
Prospective study of 12 cats with ionized hypercalcemia of idiopathic origin was identified by telephone and email communication with a convenience sample of consulting veterinarians. Cats were treated with alendronate at a dose of 5–20 mg per feline PO q7d. Serum ionized calcium concentration (iCa) was measured before beginning treatment with alendronate, and after 1, 3, and 6 months of treatment. Alendronate dosage was adjusted according to iCa. Evaluation included physical examination, CBC, biochemistry profile, and diagnostic imaging. The owners and referring veterinarians were questioned about any observed adverse effects. The Wilcoxon matched‐pairs signed rank test was used to compare baseline iCa to iCa at different time periods.Results
Alendronate treatment resulted in a decrease in iCa in all 12 cats. The median percentage change in iCa was −13.2%, −15.9%, and −18.1% (range, −29.6 to +7.6; −30.5 to −1.9; −45.8 to +1.5%) at the 1, 3, and 6 month time points, respectively. Baseline iCa was significantly different from 1 month (P = .0042), 3 months (P = .0005), and 6 months (P = .0015). No adverse effects were reported for any of the cats.Conclusions and Clinical Importance
Alendronate was well tolerated and decreased iCa in most cats for the 6‐month period of observation. 相似文献135.
136.
Photoreceptor deactivation and retinal degeneration mediated by a photoreceptor-specific protein kinase C 总被引:13,自引:0,他引:13
D P Smith R Ranganathan R W Hardy J Marx T Tsuchida C S Zuker 《Science (New York, N.Y.)》1991,254(5037):1478-1484
The protein kinase C (PKC) family of serine-threonine kinases has been implicated in the regulation of a variety of signaling cascades. One member of this family, eye-PKC, is expressed exclusively in the Drosophila visual system. The inaC (inactivation-no-afterpotential C) locus was shown to be the structural gene for eye-PKC. Analysis of the light response from inaC mutants showed that this kinase is required for the deactivation and rapid desensitization of the visual cascade. Light adaptation was also defective in inaC mutant flies. In flies carrying the retinal degeneration mutation rdgB, absence of eye-PKC suppressed photoreceptor cell degeneration. These results indicate that eye-PKC functions in the light-dependent regulation of the phototransduction cascade in Drosophila. 相似文献
137.
Summary Chambers were designed to simulate environmental conditions present in commercial potato stores and were used to introduce
condensation to tubers infected with silver scurf (Helminthosporium solani). The electrical resistance measured across the skin of tubers from the top of the chambers was consistently lower than that
from the bottom of the chamber, and this was reflected in an increased number ofH. solani spores produced by the top tubers. An increase in the length of the condensation period resulted in the skin resistance remaining
lower for a longer period and also resulted in higher number of spores. Tubers held at relatively high ambient temperatures
(15 °C) required a shorter period of condensation to cause an increase in spore count. This investigation highlighted the
need for close monitoring of store environments so that condensation events can be quickly identified and the tubers dried. 相似文献
138.
Phytophthora cinnamomi is a necrotrophic pathogen of woody perennials and devastates many biomes worldwide. A controlled perlite–hydroponic system with no other hyphae‐producing organisms as contaminants present allowed rapid assessment of ten annual and herbaceous perennial plant species most of which have a wide distribution within the jarrah (Eucalyptus marginata) forest in Western Australia where this pathogen has been introduced. As some annuals and herbaceous perennials have recently been reported as symptomatic and asymptomatic hosts, laboratory screening of some of the field‐tested annuals and herbaceous perennials and additional species was used to further evaluate their role in the pathogen's disease cycle. Nine of the species challenged with the pathogen were asymptomatic, with none developing root lesions; however, Trachymene pilosa died. The pathogen produced thick‐walled chlamydospores and stromata in the asymptomatic roots. Furthermore, haustoria were observed in the roots, indicating that the pathogen was growing as a biotroph in these hosts. 相似文献
139.
An evaluation of six methods used to index veld condition showed that the majority provided indices that were insensitive to long‐term grazing impact. However, certain species were found to either increase or decrease in relative abundance with an increase in grazing intensity. A key species method is therefore suggested to be a potentially sensitive approach for indexing veld condition in relation to grazing management in the Highland Sourveld. 相似文献
140.
A. Van Niekerk M.B. Hardy B.D. Mappledoram S.F. Lesch 《African Journal of Range and Forage Science》2013,30(2):18-21
Abstract The Highland Sourveld of Natal is an important beef producing area. Although it covers only 13% of the total area of the province, it supports 18% of the beef cattle population. The performance of cows and their calves stocked at four stocking rates on Highland Sourveld was studied. Two stocking rates were duplicated to test the benefit of an energy lick against a mineral lick. The effect of stocking rate on the veld was monitored in terms of compositional change. Stocking rate significantly affected cow performance and consequently calf performance. An energy lick supplement, as opposed to a mineral lick supplement, was beneficial at the 1,0 LSU/ha stocking rate, but not at the 1,67 LSU/ha stocking rate. The composition of the veld in the low to moderately stocked treatments changed relatively little, over the recording period, whilst the very high stocking rate treatments showed a rapid delcine in veld composition score. 相似文献