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排序方式: 共有169条查询结果,搜索用时 15 毫秒
111.
Caitlin H. Stoner Ashley B. Saunders Johanna C. Heseltine Audrey K. Cook Jonathan A. Lidbury 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2022,36(2):406
BackgroundTransesophageal echocardiography (TEE) is useful in the assessment and procedural monitoring of congenital heart disease (CHD) with a relatively low complication rate in humans.ObjectivesTo evaluate the safety of TEE and report complications in dogs.AnimalsForty client‐owned dogs with CHD.MethodsProspective observational study including gastroesophagoscopy before and after TEE imaging. TEE was planned with a GE 6VT‐D adult probe in dogs weighing ≥4 kg and a GE 10T‐D microprobe alternating with an intracardiac echocardiography probe placed in the esophagus in dogs <4 kg. Difficulties with probe placement, probe interference and TEE probe imaging times were recorded. Dogs were monitored in the recovery period after TEE using an established nausea scoring system.ResultsNew gastroesophageal abnormalities were identified after TEE in 4 dogs including 4 areas of mucosal damage involving <25% of the lower esophageal sphincter (n = 4) and 1 lesion at the heart base (n = 1) and were not attributed to longer imaging times or a specific probe. Lesions identified before TEE in 4 dogs remained unchanged after TEE. The 6VT‐D probe could not be placed in 1 dog with enlarged tonsils, and it obstructed fluoroscopic views in 3 dogs. The probes did not compress any structures in dogs in which fluoroscopy was performed (n = 20). Four dogs had evidence to suggest nausea after the procedure.Conclusions and Clinical ImportanceWhile major complications remain possible, complications in this study were mild and few in number. Dog size and probe characteristics are factors to consider when performing TEE. 相似文献
112.
Leone M. Brown Rebecca K. Fuda Nicolas Schtickzelle Haley Coffman Audrey Jost Alice Kazberouk Eliot Kemper Emma Sass Elizabeth E. Crone 《Landscape Ecology》2017,32(8):1657-1670
Context
Landscape-scale population dynamics are driven in part by movement within and dispersal among habitat patches. Predicting these processes requires information about how movement behavior varies among land cover types.Objectives
We investigated how butterfly movement in a heterogeneous landscape varies within and between habitat and matrix land cover types, and the implications of these differences for within-patch residence times and among-patch connectivity.Methods
We empirically measured movement behavior in the Baltimore checkerspot butterfly (Euphydryas phaeton) in three land cover classes that broadly constitute habitat and two classes that constitute matrix. We also measured habitat preference at boundaries. We predicted patch residence times and interpatch dispersal using movement parameters estimated separately for each habitat and matrix land cover subclass (5 categories), or for combined habitat and combined matrix land cover classes (2 categories). We evaluated the effects of including edge behavior on all metrics.Results
Overall, movement was slower within habitat land cover types, and faster in matrix cover types. Butterflies at forest edges were biased to remain in open areas, and connectivity and patch residence times were most affected by behavior at structural edges. Differences in movement between matrix subclasses had a greater effect on predictions about connectivity than differences between habitat subclasses. Differences in movement among habitat subclasses had a greater effect on residence times.Conclusions
Our findings highlight the importance of careful classification of movement and land cover in heterogeneous landscapes, and reveal how subtle differences in behavioral responses to land cover can affect landscape-scale outcomes.113.
Yukinori Mukai Audrey Daning Tuzan Sitti Raehanah Muhamad Shaleh Bernardette Mabel Manjaji-Matsumoto 《Fisheries Science》2010,76(6):921-930
Larvae of the sutchi catfish Pangasianodon hypophthalmus hatch with morphologically immature features, but sensory organs develop rapidly as the fish grow. By 1 day old, yolk-sac
larvae showed notochord flexion, and by 2 days old larvae were observed to have consumed a large part of the yolk sac. At
this stage, larvae had well-developed eyes, olfactory organs with ciliated receptor cells, inner ears with semicircular canals,
and numerous taste buds, and they commenced ingestion of rotifers, Artemia nauplii, and artificial compound feed. Two-day-old larvae had many free neuromasts on the surface of the head and flanks
and clearly showed rheotaxis. By 20 days old, free neuromasts in postflexion larvae had sunk under the skin. At this later
stage, larvae swam against a water current and schooled along the side of the fish tank. Rapid development of sensory organs
and notochord flexion would be an adaptation for survival in conditions of flowing water, as in the Mekong River. In this
study, we show that development of the lateral line in the postflexion stage seems to be closely related to larval behavior,
suggesting that these developments could be essential for sutchi catfish larvae survival. 相似文献
114.
Cole LK Luu DH Rajala-Schultz PJ Meadows C Torres AH 《American journal of veterinary research》2006,67(6):1040-1044
OBJECTIVE: To evaluate the in vitro activity of an ear rinse (ER) containing tromethamine, EDTA, and benzyl alcohol on bacterial pathogens from dogs with otitis. SAMPLE POPULATION: Organisms were collected from ear swab specimens from the external and middle ear and included Staphylococcus spp (n = 11; Staphylococcus intermedius [7] and Staphylococcus spp [4]), Pseudomonas aeruginosa (5), Proteus spp (5), beta-hemolytic streptococcus (11), and 1 control strain of each organism. PROCEDURES: 3 test solutions were evaluated including EDTA, tromethamine, and benzyl alcohol (ER); EDTA and tromethamine (ER without benzyl alcohol [ER - BA]); and purified water. Ten-milliliter aliquots of each test solution were transferred into 36 tubes and inoculated with one of the organisms. Samples were retrieved from each tube at 0, 15, 30, 45, and 60 minutes, transferred to Petri dishes, mixed with soybean-casein digest agar, and incubated. After incubation, plates were examined for growth, and the number of colonies was expressed as CFU per milliliter. RESULTS: ER significantly decreased bacterial growth in vitro of P aeruginosa and beta-hemolytic streptococcal organisms within 15 minutes, Proteus spp within 30 minutes, and Staphylococcus spp within 60 minutes. Comparatively, the presence of benzyl alcohol in ER significantly decreased bacterial growth of beta-hemolytic streptococcus and Proteus spp. CONCLUSIONS AND CLINICAL RELEVANCE: On the basis of results of this study, future studies should be performed to evaluate the in vivo efficacy of ER alone as a treatment for otic infections caused by beta-hemolytic streptococcus, P aeruginosa, and Proteus spp and of ER combined with an antimicrobial agent for otic infections caused by Staphylococcus spp. 相似文献
115.
Systolic and diastolic myocardial dysfunction in cats with hypertrophic cardiomyopathy or systemic hypertension 总被引:2,自引:0,他引:2
Carlos Sampedrano C Chetboul V Gouni V Nicolle AP Pouchelon JL Tissier R 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2006,20(5):1106-1115
BACKGROUND: Hypertrophic cardiomyopathy (HCM) and chronic systemic hypertension (SHT) can both lead to left-ventricular hypertrophy (LVH) in cats. Assessment of LVH-associated myocardial dysfunction could provide new insights in the understanding of the pathophysiology of these diseases. HYPOTHESIS: Quantification of left-ventricular free-wall (LVFW) motion using tissue Doppler imaging (TDI) could permit differentiation of feline HCM from SHT-related LVH (LVH-SHT). ANIMALS: A total of 108 cats of different breeds were enrolled in this study: 35 cats with HCM, 17 with concentric LVH and SHT, and 56 healthy cats as a control group. METHODS: All cats were examined by conventional echocardiography and 2-dimensional color TDI. RESULTS: Radial and longitudinal diastolic LVFW velocities were similarly altered in cats with HCM and LVH-SHT, compared to controls. Systolic velocities were also lower in the groups with hypertrophy than in the controls, for longitudinal but not radial motion. To determine whether these diastolic and systolic alterations could also be observed in cats without LVFW hypertrophy, we performed a subgroup analysis in cats with a normal M-mode examination, that is, with only a localized subaortic interventricular septum hypertrophy. A significant radial and longitudinal diastolic dysfunction was still observed in both the HCM and LVH-SHT groups compared to controls, and systolic dysfunction was detected in the longitudinal motion. CONCLUSIONS: LVFW motion is similarly altered in cats with HCM and LVH-SHT. This dysfunction occurs independently of the presence of myocardial hypertrophy, demonstrating that TDI is capable of detecting systolic and diastolic segmental functional changes in nonhypertrophied wall segments in cats with HCM and SHT. 相似文献
116.
Chetboul V Blot S Sampedrano CC Thibaud JL Granger N Tissier R Bruneval P Gaschen F Gouni V Nicolle AP Pouchelon JL 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2006,20(3):640-647
Diagnosis of feline hypertrophic cardiomyopathy currently is based on the presence of myocardial hypertrophy detected using conventional echocardiography. The accuracy of tissue Doppler imaging (TDI) for earlier detection of the disease has never been described. The objective of this sudy was to quantify left ventricular free wall (LVFW) velocities in cats with hypertrophic muscular dystrophy (HFMD) during preclinical cardiomyopathy using TDI. The study animals included 22 healthy controls and 7 cats belonging to a family of cats with HFMD (2 affected adult males, 2 heterozygous adult females, one 2.5-month-old affected male kitten, and 2 phenotypically normal female kittens from the same litter). All cats were examined via conventional echocardiography and 2-dimensional color TDI. No LVFW hypertrophy was detected in the 2 carriers or in the affected kitten when using conventional echocardiography and histologic examination, respectively. The LVFW also was normal for 1 affected male and at the upper limit of normal for the 2nd male. Conversely, LVFW dysfunction was detected in all affected and carrier cats with HFMD when using TDI. TDI consistently detects LVFW dysfunction in cats with HFMD despite the absence of myocardial hypertrophy. Therefore, TDI appears more sensitive than conventional echocardiography in detecting regional myocardial abnormalities. 相似文献
117.
Nicolle AP Chetboul V Tessier-Vetzel D Carlos Sampedrano C Aletti E Pouchelon JL 《The Canadian veterinary journal. La revue veterinaire canadienne》2006,47(8):792-795
A dog was presented with a history of dyspnea, coughing, and ascites. Angiostrongylosis and severe pulmonary arterial hypertension (PAH) were found, as well as a marked discordance between the electrical and mechanical events of the heart. Pulmonary arterial hypertension related to Angiostrongylus vasorum has rarely been reported. 相似文献
118.
A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans 总被引:1,自引:0,他引:1
Bricker DK Taylor EB Schell JC Orsak T Boutron A Chen YC Cox JE Cardon CM Van Vranken JG Dephoure N Redin C Boudina S Gygi SP Brivet M Thummel CS Rutter J 《Science (New York, N.Y.)》2012,337(6090):96-100
Pyruvate constitutes a critical branch point in cellular carbon metabolism. We have identified two proteins, Mpc1 and Mpc2, as essential for mitochondrial pyruvate transport in yeast, Drosophila, and humans. Mpc1 and Mpc2 associate to form an ~150-kilodalton complex in the inner mitochondrial membrane. Yeast and Drosophila mutants lacking MPC1 display impaired pyruvate metabolism, with an accumulation of upstream metabolites and a depletion of tricarboxylic acid cycle intermediates. Loss of yeast Mpc1 results in defective mitochondrial pyruvate uptake, and silencing of MPC1 or MPC2 in mammalian cells impairs pyruvate oxidation. A point mutation in MPC1 provides resistance to a known inhibitor of the mitochondrial pyruvate carrier. Human genetic studies of three families with children suffering from lactic acidosis and hyperpyruvatemia revealed a causal locus that mapped to MPC1, changing single amino acids that are conserved throughout eukaryotes. These data demonstrate that Mpc1 and Mpc2 form an essential part of the mitochondrial pyruvate carrier. 相似文献
119.
Fraipont A Van Erck E Ramery E Fortier G Lekeux P Art T 《The Canadian veterinary journal. La revue veterinaire canadienne》2012,53(3):311-314
A field test and a standardized treadmill test were used to assess fitness in endurance horses. These tests discriminated horses of different race levels: horses participating in races of 120 km and more showed higher values of VLA4 (velocity at which blood lactate reached 4 mmol/L) and V200 (velocity at which heart rates reached 200 beats per min) than horses of lower race levels. 相似文献
120.
Expression microarray as a tool to identify differentially expressed genes in horses suffering from inflammatory airway disease 下载免费PDF全文