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Quantitative autoradiography of [3H]muscimol binding in rat brain   总被引:3,自引:0,他引:3  
A simple quantitative autoradiographic technique for the study of neurotransmitter receptors that includes the use of a tritium-sensitive film permits saturation, kinetic, and competition studies of brain samples as small as 0.01 cubic millimeter. This technique was used to study [3H]muscimol binding in rat brain. Unilateral gamma-aminobutyric acid receptor supersensitivity was observed in the substantia nigra pars reticulata after production of localized lesions of the ipsilateral corpus striatum.  相似文献   
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A new high-resolution radar image of Beta Regio, a Venus highland area, confirms the presence of a major tectonic rift system and associated volcanic activity. The lack of identifiable impact craters, together with the apparent superposition of the Theia Mons volcanic structure on the rift system, suggest that at least some of the volcanic activity occurred in relatively recent geologic time. The presence of topographically similar highland areas elsewhere on Venus (Aphrodite Terra, Dali Chasma, and Diana Chasma) suggests that rifting and volcanism are significant processes on Venus.  相似文献   
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Lead poisoning was diagnosed in four primates by the finding of toxic amounts of lead in tissues. Abnormalities in the brain and spinal cord were characterized by vascular lesions and demyelination. These findings suggest a new animal model for the study of demyelination and strengthen the supposition that lead may be a factor in some idiopathic demyelinating diseases.  相似文献   
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During the second flight of the space shuttle, the measurement of air pollution from satellites (MAPS) experiment in the OSTA-1 payload acquired approximately 35 hours of radiometric measurements of the carbon monoxide mixing ratio in the middle troposphere, upper troposphere, and lower stratosphere. A gas filter radiometer operating in the 4.67-micrometer band was used to acquire the data over the region from 38 degrees N to 38 degrees S during both daytime and nighttime. The performance of the measurement system was excellent. The data reduced to date indicate the presence of significant gradients in the middle tropospheric carbon monoxide mixing ratio with both latitude and longitude over the North Atlantic, the Mediterranean Sea, and the Middle East. On the basis of comparisons with directly measured values, the accuracy of the measurements is approximately 15 percent. Comparisons of data taken on successive orbits over the same geographic region indicate that the repeatability of the measurements is approximately 5 percent.  相似文献   
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Ashton MJ, Layzer JB. Summer microhabitat use by adult and young‐of‐year snail darters (Percina tanasi) in two rivers. Ecology of Freshwater Fish 2010: 19: 609–617. © Published 2010. This article is a US Government work and is in the public domain in the USA. Abstract – We characterised microhabitat availability and use by adult and young‐of‐year (YOY) snail darters (Percina tanasi Etnier 1976 ) while snorkelling in the French Broad and Hiwassee rivers, TN, USA. Both age groups of snail darters disproportionately used most microhabitat variables compared to their availability. Snail darters primarily occupied moderately deep, swift water over gravel substrates with little macrophyte coverage and no silt. Univariate comparisons indicated that adult and YOY darters occupied different habitat, but there was no marked differences between principal components analysis plots of multivariate microhabitat use within a river. Although the availability of microhabitat variables differed between the French Broad and Hiwassee rivers, univariate means and multivariate plots illustrated that the habitats used were generally similar by age groups of snail darters between rivers. Because our observations of habitat availability and use were constrained to low flow periods and depths <1 m, the transferability of our results to higher flow periods may be limited. However, the similarity in habitat use between rivers suggests that our results can be applied to low‐normal flow conditions in other streams.  相似文献   
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