Arginylation of beta-actin regulates actin cytoskeleton and cell motility

Posttranslational arginylation is critical for mouse embryogenesis, cardiovascular development, and angiogenesis, but its molecular effects and the identity of proteins arginylated in vivo are unknown. We found that beta-actin was arginylated in vivo to regulate actin filament properties, beta-actin localization, and lamella formation in motile cells. Arginylation of beta-actin apparently represents a critical step in the actin N-terminal processing needed for actin functioning in vivo. Thus, posttranslational arginylation of a single protein target can regulate its intracellular function, inducing global changes on the cellular level, and may contribute to cardiovascular development and angiogenesis.     

Contemporary and emerging fisheries in The Bahamas—Conservation and management challenges,achievements and future directions

The harvest of marine resources has long‐standing cultural and economic importance to The Bahamas and other small island developing states. Tourists and residents place a demand on local marine resources, particularly Caribbean spiny lobster, Panulirus argus (Latreille), queen conch, Lobatus gigas (Linnaeus) and Nassau grouper, Epinephelus striatus (Bloch), and many fishery products are also sold on the global market. Illegal, unreported and unregulated fishing coupled with inadequate regulations and enforcement are the main factors contributing to the decline of Bahamian fisheries along with other anthropogenic impacts. This article reviews the status of fisheries management in The Bahamas using economically and ecologically important species as case studies to highlight conservation successes, knowledge gaps and deficiencies in existing management approaches. The review concludes with an examination of how emerging fisheries and improved conservation management strategies have the potential to improve economic and food security throughout the archipelago.     

Seasonal acoustic occurrence of blue,fin, and North Atlantic right whales in the New York Bight

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Does motor noise from recreational boats alter parental care behaviour of a nesting freshwater fish?

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Evaluation of 10-year temporal and spatial variability in structure and growth across contrasting commercial thinning treatments in spruce-fir forests of northern Maine,USA

Key message

Detailed measures of growth pattern and structural heterogeneity applied in this study helped to quantify the immediate effects of various thinning regimes on forest structure and the resulting alterations in tree size as well as observed longer term stand dynamics.

Context

Forest management, stand structure, and tree growth are highly inter-correlated. Prior analyses, however, have resulted in mixed outcomes with limited success in revealing ecological mechanisms.

Aims

The study aimed at evaluating the relationship between forest structure and stand dynamics by applying several sophisticated measures of growth pattern and structural heterogeneity.

Methods

Data from a controlled and fully stem-mapped commercial thinning experiment with seven contrasting treatments including a non-thinned control at six locations across the Acadian Forest of Maine, USA, was used. Stand-level attributes examined included tree size and growth heterogeneity, spatial tree distribution, and growth dominance.

Results

Thinning generally reduced stand structural heterogeneity compared to the non-thinned control. In addition, the spatial arrangement of trees changed from fully random (non-thinned control) to a more clustered (removal of dominant and co-dominant individuals) or regular distribution (removal of intermediate and suppressed individuals). Overall, stand growth exhibited increasing (non-thinned control, removal of intermediate and suppressed individuals) or decreasing growth dominance of large trees (removal of co-dominant competitors). Forwarder trails increased basal area growth of individual trees up to a distance from the trail of approximately 5 m.

Conclusion

Findings of this study validate an earlier insight according to which interactions between management practices, forest structure, and tree growth form a permanent feedback loop.

     

Has agriculture dispersed worldwide from a single origin?

Some eleven thousand years ago hunter–gatherers in the Near East initiated their transition to farming using an assemblage of eight founder crops: three cereals, four legumes and flax. The evidence show that each of these plant species was brought into domestication once or mostly twice, with no further redomestication. It seems that these species were carefully chosen by humans from the many hundreds of plants used. Apparently, these eight crops were those that best responded to the sowing–reaping agrotechnique, reflecting the biological factors that were later manifested in the success of these founder crops. While changing their own life style, the novel, successful farmers have gained extra food, prestige, property, power, and as a result more spouses and children, eventually leading to their higher biological fitness. This in turn led to the expansion of agriculture either by idea diffusion or by the dispersal of the farmers themselves with their original founder crops. Farming has dispersed to Europe, Asia and North Africa during the following millennia. Concurrently, other remote hunter–gatherer populations in additional worldwide centers, notably East Asia and the Americas have also moved to farming life, conceiving local plant species and the relevant agrotechniques. Regarding the life history of the various cultivated plant species and the capabilities of our ancestors it is suggested that the simplest explanation for the beginning of agriculture in the new worldwide centers is the idea diffusion to these remote areas.     

Balanced nutrient density for broiler chickens using a range of digestible lysine-to-metabolizable energy ratios and nutrient density:Growth performance,nutrient utilisation and apparent metabolizable energy

Currently, specific nutrient concentration, metabolizable energy (ME) and digestible amino acids are used as feed formulation criteria. A balanced nutrient density (BND) concept based on 2 criteria of nutrient density and balanced amino acids-to-ME ratio may offer more flexibility in optimisation of profit in formulation of diets compared with current formulation based on set values per unit of feed mass. A total of 672 one-d-old off-sex male Ross 308 broiler chickens were used across two 42-d performance trials in a 3 × 2 factorial arrangement of treatments with each diet replicated 8 times (14 birds per replicate). The experimental factors were 2 nutrient density levels (low [LD] and high [HD]) and 3 digestible lysine-to-ME ratios (DLYS:ME; low, medium, and high). Low density diets had ME of 2,876 and 3,023 kcal/kg for starter and finisher, respectively, while values for HD diets were 3,169 and 3,315 kcal/kg with proportionally higher non-nitrogenated nutrients. Separate digestibility and apparent metabolizable energy (AME) assays were conducted at d 21 and 42. Digestibility assays at d 7 were conducted on birds used for performance trials. Regardless of the diet density, birds fed low DLYS:ME had a lower (P < 0.01) feed intake (d 0 to 42) than medium and high DLYS:ME. Without interaction, birds fed low and medium DLYS:ME had a similar body weight gain being the heaviest while birds low DLYS:ME were the lightest. By an interaction (P < 0.05), the highest overall FCR value was observed for birds fed LD × low DLYS:ME and improved linearly when DLYS:ME increased to the highest level reaching a limit for birds fed HD × medium DLYS:ME. Calorie conversion linearly decreased (P < 0.001) with increments in DLYS:ME. Jejunal and ileal starch and protein digestibility were affected on d 21 and 42 but not on d 7 of age. Given the independence of response on BW and feed consumption, the use of BND as a flexible system in diet formulations has the potential to enable more accurate formulation for optimisation of growth performance of broiler chickens.