Significance of CD117 and CD34 expression in gastrointestinals tromal tumors

AIM:In this article,gastrointestinal tumo r-related historical ar chives of pathology in our hospital were reviewed in order to acknowledge gastro intestinal stromal tumors (GIST).METHODS:These cases were rediagnosed correctly ,these tissues were labeled with some antibodies such as CD117,CD34,α-SMA,S-100,and the ir clinical characteristics were explored.RESULTS:CD117,CD34 were expressed widely in GISTs ,the percen tage of positive expression was CD117 （50/56,89.3%）,CD34 （37/56,66.1% ）,respectively,α-SMA,S-100 were （17/56,30.4%）,（4/56,7.1%）,re spe ctively,desmin was negative in these cases.Among them,29 cases were benign a nd borderline,27 cases were malignant.The percentage of occurring in stomach a nd intestine was 91.1%.CONCLUSION:CD117,CD34 are expressed significantly in GIST,t hese might be assistant markers for GIST diagnosis.GISTs mostly occurred in sto mach and intestine.     

强普生Ⅲ号对H5N1亚型禽流感病毒的杀灭试验

强普生Ⅲ号是以多种植物为原料,采用科学方法提练精制而成的中草药,其富含鞣质、毛莨黄素、生物碱、酚类、黄酮甙、靛甙、蒽醌甙等物质,能增强动物机体的免疫功能.提高动物机体抗应激的能力,有很好的抗病毒作用。与常用的消毒药物相比较,强普生Ⅲ号具有不含任何化学物质,无毒副作用、不易产生耐药性、无残留的特点。本试验结果表明:强普生Ⅲ号与禽流感病毒作用10分钟后,原液、1:5、1:10、1:20、1:40、1:80的受试液对病毒的杀灭率均为100%,有完全的杀病毒作用, 是一种理想的绿色环保型消毒剂。     

非洲菊切花保鲜剂的研究

本文研究由蔗糖、硝酸银、8-HQ(8-羟基喹啉)配制的不同保鲜剂对非洲菊切花插瓶寿命、水分平衡、鲜重变化及观赏值等指标的影响。结果表明：4％蔗糖 200mg／L硝酸银 200mg／L硫酸铝 320mg／L8-HQ的保鲜效果最好。     

中国主要纸产品国际竞争力综合评价

文中在分析中国主要纸产品出口贸易现状的基础上,选取国际市场占有率、贸易竞争力指数和显示性比较优势指数测算中国主要纸产品2010-2019年的国际竞争力指数,并采用基于主成分分析的定权方法对纸产品国际市场竞争力进行综合评价。结果表明:主要纸产品国际竞争力较强的芬兰、瑞典和德国位居综合评价前3位,中国主要纸产品综合竞争力经过近10年发展已处于中等偏上水平,仍有改进和提升空间。基于上述研究成果,提出推进人工林速生材高效利用、促进科技创新能力提升和探索"出口转内销"等政策建议。     

蜂花粉抗化学性肝损伤研究进展

近年来研究发现蜂花粉具有显著的保肝功效,国内外学者已对此开展了广泛而深入的研究。本文就蜂花粉及活性成分对化学性肝损伤(四氯化碳肝损伤、酒精性肝损伤、氨基半乳糖诱导肝损伤)的作用效果和作用机理等方面的研究进展进行了综述,并对其研究方向和前景进行展望。     

河南省饲料企业营销中存在的问题与对策

20年来,河南省饲料业一直保持迅速发展的良好趋势。2004年全省饲料工业总产量达到688.7万t,产值达到134亿元,分别比1996年增长143%和127%,其中浓缩饲料总量达到245万t,添加剂预混合饲料达到13.1万t,分别比1996年增长了4.8倍和3倍。但近几年,河南省饲料业在快速发展过程中呈现出     

聚醚类抗生素——腐霉素发酵条件的研究

由吸水链霉菌 （Ｓｔｒｅｐｔｏｍ ｙｃｅｓｈｙｇｒｏｓｃｏｐｉｃｕｓ）ＨＳ－ ８６诱变获得的一株突变株Ｕ－５８,通过设计的多因子试验,确定了培养该菌株的最佳碳、氮源比,诸因子中影响最大的是淀粉,其次是蛋白胨、酵母粉。原材料对比试验中,淀粉以玉米淀粉最佳。锰离子对腐霉素产量的提高有显著的促进作用。在２．５ｔ发酵罐中通气培养９６～１２０ｈ,效价达到４ ０００μｇ／ｍ ｌ以上。     

我国丝绸面临的困境及成因浅析

丝绸业是以茧丝绸为纽带 ,以出口创汇为主的跨越农工贸的外向型行业 ,现在我国的蚕茧和生丝产量分别约占世界总产量的78%和 72 % ,丝类、绸缎和丝绸服饰的出口量分别约占世界贸易的 90 %、50 %和 45% ,1 950～ 1 998年间丝绸出口创汇达 42 2 .1 2亿美元 ,在世界丝绸业和国民经济中占有重要的地位。1　我国丝绸业面临的困境80年代后期 ,我国丝绸行业高速发展 ,产量大幅攀升 ,出口量迅猛增加 ,但至 90年代中期 ,全行业发生前所未有的亏损 ,近来 ,以加入ＷＴＯ为契机 ,行业情况有所好转 ,但也仍在困境中艰难跋涉 ,发展前景不容盲目乐观。自 1 9…     

Radiosensitivity of canine osteosarcoma cells transfected with wild‐type p53 in vitro*

The p53 gene is one of the important tumour suppressor genes that are involved with the cell survival signal pathway. One of the major functions of the p53 protein is to organize cell cycle regulation and induction of apoptosis for cellular genetic stability. It has been documented that more than 50% of all human cancers include a p53 mutation. We evaluated the difference in radiosensitivity between upregulating the expression of canine wild‐type p53 (cp53) in cultured osteosarcoma (D17) cells and naive D17 cells in vitro. We found that upregulating transfected cp53 D17 cells increased their radiation sensitivity in vitro, and there was a significant decrease (P < 0.009) in survival between cp53‐transfected D17 cells and naive D17 cells. In this experiment, a p53 enhancement ratio (p53ER) reached approximately 3.0 at high doses. The transfected cp53 D17 cells were significantly more radiosensitive at all doses evaluated than naive D17 cells, except at 1 Gy where too few data points were available. The p53ER increased rapidly at doses less than 4 Gy, achieving a maximum of about 3.0 for doses of 4 Gy and above. This study shows the enhanced radiosensitivity of the transfected p53 at clinically relevant doses.     

三种药用甘草种子对盐渍环境的萌发响应及其适宜生态种植区

根据西北地区盐碱土的盐分组成特点,选择NaCl、Na₂SO₄、NaHCO₃ 3种单盐,通过盐胁迫下3种药用甘草种子萌发特性、萌发进程、胚生长、种子活力及复水后萌发率的差异分析,比较3种药用甘草种子对不同土壤盐分的萌发响应、耐盐阈值及其适宜盐碱地种植区,为盐碱地种植药用甘草适宜生态区的选择提供理论参考。结果表明,3种单盐胁迫不同程度降低了药用甘草种子的萌发率,延长种子的萌发时间,抑制胚轴伸长生长,盐害强弱顺序为:NaHCO₃＞Na₂SO₄ ＞NaCl。NaCl和Na₂SO₄对药用甘草种子萌发的抑制效应主要为渗透效应,盐胁迫解除复水后种子萌发恢复率为50.6%～78.5%;NaHCO₃ 对药用甘草种子萌发的抑制效应主要为离子毒害,种子萌发恢复率仅为5.1%～21.5%;胀果甘草耐盐性最强,适宜在以氯化物-硫酸盐为主的总盐量为0～1.3%的区域种植,光果甘草耐NaHCO₃最强,可在含小苏打的弃耕低盐地种植,乌拉尔甘草耐盐性最弱,种植地土壤的总盐量范围在0～0.7%为宜。