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An abdominal cystic lymphangiomatosis in a Mt. Carmel blind mole rat (Nannospalax (ehrenbergi) carmeli) is described. This case was most likely due to a congenital abnormality with long-term compensation by the animal. The case describes the clinical course and subsequent postmortem examination. The death in the animal was caused by an abscess in the peritoneal wall and subsequent peritonitis.  相似文献   
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The toxicity of the S-methyl isomer of fenitrothion was found to be higher than that of both fenitrothion and technical fenitrothion. Repeated administration of the compound showed a rapid decrease in toxicity with decreasing doses.Excretion of p-nitro-m-cresol into the urine of rats was more rapid and the excreted amounts were larger from a single dose of the isomer than from fenitrothion.Single doses of the isomer increased the pentobarbitone sleeping time in mice at both 24 and 48 hr, but showed no change after 4 days. Administration of the isomer and purified fenitrothion to mice for 1 week had no effect on the pentobarbitone sleeping time, nor did a single dose of fenitrothion change the effectiveness of pentobarbitone.Dominant lethal tests in rats revealed a possible mutagenic effect from this compound.The anticholinesterase activity of the fenitrothion S-methyl isomer in vitro was found to be two to three times higher than that of fenitrothion.  相似文献   
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The success or failure of an investment project in fruit production also depends on the selection of the fruit species and variety. When selecting the variety for the creation of a new orchard it is necessary to perform the synthesis of different data and to look at all aspects of the investment. This paper presents the application of DEX multi-criteria decision making. The model was applied on 7 varieties of plum from the western Balkans region that were assessed by experts from “The association of agricultural economists of Western Balkans” using the Delphi method.By applying this model it has been shown that the ’Stanley’ is the most suitable for starting a new orchard while the varieties ’?a?anska ljepotica’ and ’?a?anska rodna’ are also very suitable for starting new fruit orchards and they have also received the value attribute “very acceptable”.Using this model all strong and weak sides of the observed plum variety were shown. For the final selection it is necessary to conduct research at a specific micro location where all characteristics of that area would also be taken into consideration.  相似文献   
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Abstract Recreational fisheries statistics can provide valuable information on the dynamics of fish stocks and their exploitation. For some reservoirs in the Czech Republic, there are conspicuous synchronous fluctuations in catches of different species that might be caused by fishing skills and strategies. This study describes a method that could detect signatures of such phenomena in individual logbooks. It classifies anglers by species reported during 1 year and compares the resulting angler groups by group size, fishing effort, catch per unit effort (CPUE) and annual catch. The method is illustrated by data from one reservoir, showing that the number of generalist anglers who caught several species was higher than expected. Generalists also had higher catches and effort but lower CPUE than specialists who caught only one of the species. The results indicate that generalist anglers with a low degree of specialisation and high effort could contribute to long‐term correlations in species catches.  相似文献   
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ObjectiveTo investigate the pharmacokinetics of carprofen after a single intravenous (IV) dose and multiple oral doses administered to pigs undergoing electroporation of the pancreas.Study designProspective experimental study.AnimalsA group of eight female pigs weighing 31.74 ± 2.24 kg (mean ± standard deviation).MethodsCarprofen 4 mg kg?1 was administered IV after placement of a central venous catheter during general anaesthesia with isoflurane. Blood samples were collected 30 seconds before and 5, 10, 20, 30 and 60 minutes and 2, 4, 6, 8, 12 and 24 hours after carprofen administration. Subsequently, the same dose of carprofen was administered orally, daily, for 6 consecutive days and blood collected at 36, 48, 60, 72, 96, 120, 144 and 168 hours after initial carprofen administration. Plasma was analysed using liquid chromatography with mass spectrometry. Standard pharmacokinetic parameters were calculated by compartmental analysis of plasma concentration–time curves. Data are presented as mean ± standard error.ResultsThe initial plasma concentration of IV carprofen was estimated at 54.57 ± 3.92 μg mL?1 and decreased to 8.26 ± 1.07 μg mL?1 24 hours later. The plasma elimination curve showed a bi-exponential decline: a rapid distribution phase with a distribution half-life of 0.21 ± 0.03 hours and a slower elimination phase with an elimination half-life of 17.31 ± 3.78 hours. The calculated pharmacokinetic parameters were as follows: the area under the plasma concentration–time curve was 357.3 ± 16.73 μg mL?1 hour, volume of distribution was 0.28 ± 0.07 L kg?1 and plasma clearance rate was 0.19 ± 0.009 mL minute?1 kg?1. The plasma concentration of carprofen, administered orally from days 2 to 7, varied from 9.03 ± 1.87 to 11.49 ± 2.15 μg mL?1.Conclusions and clinical relevanceCarprofen can be regarded as a long-acting non-steroidal anti-inflammatory drug in pigs.  相似文献   
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The contamination of a karstic aquifer by the leachate from the urban solid waste landfill of La Mina (Marbella, south of Spain) has been monitored. A characterization of the karstic media and the different storages of water in the carbonate rock have been deduced by the study of the hydrodynamic and hydrochemical variations in water points of the study network. The chemical compositions of four springs, three pumping wells and five piezometers in the surroundings of the landfill, yield two patterns of hydrochemical behaviour at the contaminated points: (1) the contamination at the piezometers, measured by the concentration of Cl? and by electrical conductivity, increased over time, but was associated with the precipitation of calcite, evidenced by a reduction in the concentration of HCO3 ? and Ca2+; (2) at points near the landfill, contamination also increased, but the CO2 from the landfill provoked an additional dissolution of carbonate minerals, a process reflected in the high concentrations of hydrogen carbonate, calcium and magnesium. The contaminated points were irregularly distributed, the most distant piezometer presenting the greatest impact, whereas no traces of contamination were detected at one piezometer close to the landfill. The irregular distribution of these processes is explained by the heterogeneity of the karstic media, with different types of storage (conduits, fractures/fissures and matrix) and a difference in density between the leachate and the groundwater.  相似文献   
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