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排序方式: 共有1298条查询结果,搜索用时 46 毫秒
91.
Gary Jackson Yuk W. Cheng 《Journal of Agricultural, Biological & Environmental Statistics》2001,6(2):243-257
Snapper (Pagrusauratus) stocks found inside Shark Bay, Western Australia, are the basis of important recreational fisheries. An evaluation of the daily egg production method for annual snapper stock assessment commenced in 1997. Initial spawning biomass estimates were inconclusive due to wide confidence intervals around egg production in particular. In 1998, more comprehensive surveys were conducted in an effort to improve the accuracy and precision of the estimated parameters. Egg survey design used information on the location of the main spawning areas and spawning times identified in 1997 and employed a systematic stratified adaptive sampling approach. Further refinements to the daily egg production method included use of nonlinear regression and nonparametric bootstrapping techniques. Results are discussed in relation to the precision of parameter estimates, with reference to egg production in particular, and the appropriateness of analytical methods used. 相似文献
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94.
Heterogeneous reaction probabilities, solubilities, and the physical state of cold volcanic aerosols
Toon O Browell E Gary B Lait L Livingston J Newman P Pueschel R Russell P Schoeberl M Toon G Traub W Valero FP Selkirk H Jordan J 《Science (New York, N.Y.)》1993,261(5125):1136-1140
On 19 January 1992, heterogeneous loss of HNO(3), ClNO(3), and HCl was observed in part of the Mount Pinatubo volcanic cloud that had cooled as a result of forced ascent. Portions of the volcanic cloud froze near 191 kelvin. The reaction probability of ClNO(3) and the solubility of HNO(3) were close to laboratory measurements on liquid sulfuric acid. The magnitude of the observed loss of HCl suggests that it underwent a heterogeneous reaction. Such reactions could lead to substantial loss of HCl on background sulfuric acid particles and so be important for polar ozone loss. 相似文献
95.
Sutter NB Bustamante CD Chase K Gray MM Zhao K Zhu L Padhukasahasram B Karlins E Davis S Jones PG Quignon P Johnson GS Parker HG Fretwell N Mosher DS Lawler DF Satyaraj E Nordborg M Lark KG Wayne RK Ostrander EA 《Science (New York, N.Y.)》2007,316(5821):112-115
The domestic dog exhibits greater diversity in body size than any other terrestrial vertebrate. We used a strategy that exploits the breed structure of dogs to investigate the genetic basis of size. First, through a genome-wide scan, we identified a major quantitative trait locus (QTL) on chromosome 15 influencing size variation within a single breed. Second, we examined genetic variation in the 15-megabase interval surrounding the QTL in small and giant breeds and found marked evidence for a selective sweep spanning a single gene (IGF1), encoding insulin-like growth factor 1. A single IGF1 single-nucleotide polymorphism haplotype is common to all small breeds and nearly absent from giant breeds, suggesting that the same causal sequence variant is a major contributor to body size in all small dogs. 相似文献
96.
Yankovskaya V Horsefield R Törnroth S Luna-Chavez C Miyoshi H Léger C Byrne B Cecchini G Iwata S 《Science (New York, N.Y.)》2003,299(5607):700-704
The structure of Escherichia coli succinate dehydrogenase (SQR), analogous to the mitochondrial respiratory complex II, has been determined, revealing the electron transport pathway from the electron donor, succinate, to the terminal electron acceptor, ubiquinone. It was found that the SQR redox centers are arranged in a manner that aids the prevention of reactive oxygen species (ROS) formation at the flavin adenine dinucleotide. This is likely to be the main reason SQR is expressed during aerobic respiration rather than the related enzyme fumarate reductase, which produces high levels of ROS. Furthermore, symptoms of genetic disorders associated with mitochondrial SQR mutations may be a result of ROS formation resulting from impaired electron transport in the enzyme. 相似文献
97.
Wardle DA Yeates GW Barker GM Bellingham PJ Bonner KI Williamson WM 《Science (New York, N.Y.)》2003,301(5640):1717-1720
Although island attributes such as size and accessibility to colonizing organisms can influence community structure, the consequences of these for ecosystem functioning are little understood. A study of the suspended soils of spatially discrete epiphytes or treetop "islands" in the canopies of New Zealand rainforest trees revealed that different components of the decomposer community responded either positively or negatively to island size, as well as to the tree species that the islands occurred in. This in turn led to important differences between islands in the rates of ecosystem processes driven by the decomposer biota. This system serves as a model for better understanding how attributes of both real and habitat islands may affect key ecosystem functions through determining the community structure of organisms that drive these functions. 相似文献
98.
Klein RF Allard J Avnur Z Nikolcheva T Rotstein D Carlos AS Shea M Waters RV Belknap JK Peltz G Orwoll ES 《Science (New York, N.Y.)》2004,303(5655):229-232
The development of osteoporosis involves the interaction of multiple environmental and genetic factors. Through combined genetic and genomic approaches, we identified the lipoxygenase gene Alox15 as a negative regulator of peak bone mineral density in mice. Crossbreeding experiments with Alox15 knockout mice confirmed that 12/15-lipoxygenase plays a role in skeletal development. Pharmacologic inhibitors of this enzyme improved bone density and strength in two rodent models of osteoporosis. These results suggest that drugs targeting the 12/15-lipoxygenase pathway merit investigation as a therapy for osteoporosis. 相似文献
99.
Kleck GD 《Science (New York, N.Y.)》2005,309(5741):1675-6; author reply 1675-6
100.
Firestein GS 《Science (New York, N.Y.)》2007,315(5814):952-953