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排序方式: 共有161条查询结果,搜索用时 15 毫秒
71.
The effects of migration on the immunity of Black-Headed Gulls (Chroicocephalus ridibundus: Laridae)
Nana USHINE Osamu KURATA Yoshikazu TANAKA Tatsuo SATO Yoshihiro KURAHASHI Shin-ichi HAYAMA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2020,82(11):1619
In order to elucidate the relationship between migration period and immunity related to susceptibility, we conducted research on Black-headed gulls (Chroicocephalus ridibundus). We captured 260 gulls and collected their peripheral blood. Their leukocyte (WBC) count, percentages of heterophils (Het) and lymphocytes (Lym), heterophil and lymphocyte ratio (H/L ratio), and CD4 and CD8α expression levels (CD4 and CD8α, respectively) were quantitatively analyzed over three migration periods (Autumn migration, Wintering, Spring migration). In Adult gulls, WBC counts and CD4 levels significantly increased. Moreover, the Het and H/L ratio decreased from the Autumn migration to Wintering. Conversely, only WBC counts and CD4 levels measurements significantly decreased from Wintering to Spring migration (P<0.05). The tested parameters of the Tokyo-bay population show a greater significant difference than the measurements of immunity of the Mikawa-bay population. This study suggests that the migratory period has a negative effect on an aspect of the immune system. Including the period-difference in the immune systems in the local population, it is necessary to investigate the relationship between the ecology of migratory birds and their immunity. 相似文献
72.
73.
Tanaka Y Hosokawa M Miwa T Watanabe T Yazawa S 《Journal of agricultural and food chemistry》2010,58(22):11762-11767
Capsinoids are a group of nonpungent capsaicinoid analogues produced in Capsicum fruits. They have similar bioactivities to capsaicinoids such as suppression of fat accumulation and antioxidant activity. They are more palatable ingredients in dietary supplements than capsaicinoids because of their low pungency. Previous studies on nonpungent Capsicum annuum cultivars showed that capsinoid biosynthesis is caused by loss-of-function putative aminotransferase (p-amt) alleles. This study showed that three mildly pungent cultivars of Capsicum chinense (Zavory Hot, Aji Dulce strain 2, and Belize Sweet) contain high levels of capsinoid. It was shown that these cultivars have novel p-amt alleles, which contain mutations that differ from those of C. annuum. Sequence analysis of p-amt in Belize Sweet revealed that a 5 bp insertion (TGGGC) results in a frameshift mutation. A transposable element (Tcc) was found in the p-amt of Zavory Hot and Aji Dulce strain 2. Tcc has features similar to those of the hAT transposon family. This was inserted in the fifth intron of Zavory Hot and in third intron of Aji Dulce strain 2. The p-amt alleles harboring Tcc cannot produce an active p-AMT. These mildly pungent cultivars will provide a new natural source of capsinoids. 相似文献
74.
SUMMARY: Adenocarcinomatous growths comprising glandular cavities surrounded by cuboidal to low columnar cells and a large amount of mucus produced by the mucous cells, were observed in the the gastric lymph nodes of a harbor seal Phoca largha. The seal was stranded on the coast of Toyama Bay, Sea of Japan, on 2 March, 1998. Necroscopic examination also showed the animal had significant signet ring cell carcinoma in the stomach, as has been reported elsewhere. The adenocarcinoma may have developed from metastatic cells arising in the gastric carcinoma. 相似文献
75.
T Kosaka M Kuwabara F Koide 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》1992,54(5):875-879
Natural cytotoxicity against bovine leukemia cells (PC-3 cells) was found in bovine peripheral blood lymphocytes (PBL), and in non-adherent cells but not in adherent cells to nylon-wool column. Natural cytotoxic cells (NCC), which have natural cytotoxic activity, are found in T cell-rich fraction. When NCC were cocultured with PC-3 cells, natural cytotoxic factor (NCF) was released rapidly from NCC, and dose-response curve for NCF was almost linear induction. Cytotoxicity against PC-3 cells by NCC or NCF was increased with an increment of incubation period. Cytotoxicity against K562 cells, CL-1 cells, M1 cells or EL-4 cells by NCF was almost the same level as that against PC-3 cells, but that against those cell lines by NCC was not found. NCF activity in culture fluid from NCC cocultured with K562 cells or CL-1 cells was lower than that from NCC cocultured with PC-3 cells. 相似文献
76.
Kuwabara JS 《Science (New York, N.Y.)》1982,216(4551):1219-1221
It has been suggested that naturally occurring copper and zinc concentrations in deep seawater are toxic to marine organisms when the free ion forms are overabundant. The effects of micronutrients on the growth of gametophytes of the ecologically and commercially significant giant kelp (Macrocystis pyrifera) were studied in defined media. The results indicate that toxic copper and zinc ion concentrations as well as cobalt and manganese deficiencies may be among the factors controlling the growth of marine organisms in nature. 相似文献
77.
Malik FI Hartman JJ Elias KA Morgan BP Rodriguez H Brejc K Anderson RL Sueoka SH Lee KH Finer JT Sakowicz R Baliga R Cox DR Garard M Godinez G Kawas R Kraynack E Lenzi D Lu PP Muci A Niu C Qian X Pierce DW Pokrovskii M Suehiro I Sylvester S Tochimoto T Valdez C Wang W Katori T Kass DA Shen YT Vatner SF Morgans DJ 《Science (New York, N.Y.)》2011,331(6023):1439-1443
Decreased cardiac contractility is a central feature of systolic heart failure. Existing drugs increase cardiac contractility indirectly through signaling cascades but are limited by their mechanism-related adverse effects. To avoid these limitations, we previously developed omecamtiv mecarbil, a small-molecule, direct activator of cardiac myosin. Here, we show that it binds to the myosin catalytic domain and operates by an allosteric mechanism to increase the transition rate of myosin into the strongly actin-bound force-generating state. Paradoxically, it inhibits adenosine 5'-triphosphate turnover in the absence of actin, which suggests that it stabilizes an actin-bound conformation of myosin. In animal models, omecamtiv mecarbil increases cardiac function by increasing the duration of ejection without changing the rates of contraction. Cardiac myosin activation may provide a new therapeutic approach for systolic heart failure. 相似文献
78.
Yukie Shiobara Mioko Yoshino Atsuko Uragami Ani Widiastuti Akifumi Omori Keiko Kuba Harufumi Saito Yukimasa Hirata Takahiro Sonoda Takeharu Koizumi Tatsuo Sato 《Euphytica》2011,177(1):91-97
Asparagus (Asparagus officinalis L.) is a dioecious plant. In general, male and female plants are used for open-field culture and intensive cultivation, respectively. Farmers distinguish between the sexes by observing the form of the flower organs. However, because flowering begins 2?C3 years after planting, the sexes cannot be differentiated at transplantation by using this method, and planting of an all-male population is not possible. In this study, the usefulness of loop-mediated isothermal amplification (LAMP), a simple method of gene amplification, for sex distinction at the DNA level was determined. In addition, the phenotypic differences in seeds and seedlings of male and female plants were investigated for application as a method of early sex distinction. By using the LAMP method, the sex could be correctly identified in 100% of the seedlings, suggesting that this method is effective for sex distinction at the gene level. Principal component analysis was conducted with 11 selected parameters after investigating the seeds and seedlings of both male and female plants. The results revealed that male plants tend to have many stalks or cladophylls and female plants tend to have large plant forms, suggesting that the sexes can be distinguished by the external appearance of the seedlings before planting. LAMP and observation of the seedling phenotypes could be useful methods of sex distinction for increasing the efficiency of asparagus breeding. 相似文献
79.
Tatsuo Hayase 《Soil Science and Plant Nutrition》2013,59(3):120-126
Der größere Teil des Stickstoffhaltiges Düngesmittels sind anorganische Substanzen, und nur das Harnstoff und Kalkstickstoff können organische genannt werden, aber seine Geschwindigkeiten der Zersetzung im Boden sind ziemlich schnell, also sie haben keine dauernde Wirkung, sondern haben schnell Düngewirkung. 相似文献
80.
Tatsuo Hayase 《Soil Science and Plant Nutrition》2013,59(4):174-178
Im ersten Bericht (1) wir beschrieben eine Weise die rein Monomethlolharnstoff im große Ausbeute darstellt, aber es ist unklar, ob dem Düngemittel oder einem Bestandteil des komplex Düngemittel, Monomethylolharnstoff angemesst ist oder nicht. Also, wir untersuchten einige Eigenschaften wie folgt. 相似文献