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排序方式: 共有333条查询结果,搜索用时 78 毫秒
331.
Kitahashi T Ikawa S Sakamoto A Nomura Y Tsujiuchi T Shimizu K Sasabe S Park EY Nakamura Y Tsutsumi M Sato K 《Journal of agricultural and food chemistry》2012,60(4):940-945
A water extract of shark cartilage was fractionated into acidic and basic fractions by preparative isoelectric focusing on the basis of the amphoteric nature of samples. The acidic fraction was further fractionated into ethanol-soluble and -precipitate fractions. After the carcinogenesis treatment using N-nitrosobis(2-oxopropyl)amine, hamsters received a diet containing each fraction or purified chondroichin sulfate to give 0.4% (w/w) for 50 days. Only administration of the acidic ethanol-precipitate-fraction-containing diet significantly increased serum inhibitory activity against matrix metalloproteinase (MMP)-9 and reduced the number of adenocarcinomas in the pancreatic duct. The active fraction predominantly consisted of chondroichin sulfate-containing proteoglycan. However, the purified chondroichin sulfate had no significant activity. These results suggest that the protein moiety of the proteoglycan might be involved in the increase of serum inhibitory activity against MMP-9 and suppression of pancreatic carcinogenesis in hamster. 相似文献
332.
Maeda Ai Minoshima Ayaka Kawano Shinji Nakamura Misa Takushi Tetsuya Yamashiro Maki Kawamura Futoshi Oshiro Atsushi Ichinose Katsuya Okada Yoshihiro Rossman Amy Y. Hirooka Yuuri 《Journal of General Plant Pathology》2022,88(1):33-40
Journal of General Plant Pathology - Foot rot, also known as stem rot or tuber-root rot syndrome, on sweet potato occurs in sweet potato fields in Okinawa, Japan. Isolates of one fungal species... 相似文献
333.
Shoshi Mizuta Yuuki Koizumi Shiori Inoue Chiaki Someya Masatomi Hosoi Yoshihiro Yokoyama Reiji Yoshinaka 《Fisheries Science》2013,79(5):833-839
A large size (400 kDa) non-collagenous protein was detected as a major component in the extract, with neutral salt solution, from the dermis of sea cucumber Apostichopus armata. On SDS-PAGE analysis, the 400 K component shifted to a lower molecular weight component (about 200 K) by reduction with 2-mercaptoethanol, and they were both reactive for periodic acid-Schiff (PAS) reaction staining. From these results, this protein was suggested to be a glycoprotein consisting of disulfide-bonded two subunits with almost equal molecular weight (200 K). In addition to relatively high contents (>100/1,000 residues) of aspartic and glutamic acids, cysteine was also detected (6.1/1,000 residues) in amino acid analyses of this protein partially purified by anion-exchange column chromatography. These combined results suggest the structural similarity of the 400 K component to fibronectins from other vertebrate and invertebrate animals. 相似文献