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991.
992.
F. YANG N. SUN Y. X. SUN Q. SHAN H. Y. ZHAO D. P. ZENG Z. L. ZENG 《Journal of veterinary pharmacology and therapeutics》2013,36(2):192-200
Yang, F., Sun, N., Sun, Y. X., Shan, Q., Zhao, H. Y., Zeng, D. P., Zeng, Z. L. A physiologically based pharmacokinetics model for florfenicol in crucian carp and oral‐to‐intramuscular extrapolation. J. vet. Pharmacol. Therap. 36 , 192–200. In this study, an oral physiologically based pharmacokinetics (PBPK) model was developed for florfenicol in crucian carp (Carassius auratus). Subsequently, oral‐to‐intramuscular extrapolation was performed and the two models were used to predict florfenicol concentrations in the edible tissues of crucian carp. The oral model gave good predictions in most tissues, except for kidney and liver in which the florfenicol concentrations were underestimated at the later time points. In contrast, using the intramuscular model, the concentrations in the kidney were overestimated at the later time points. Both models had the best predictive ability in the main edible tissue, the muscle. The oral model also accurately predicted the florfenicol concentrations in the muscle after multiple doses. The present study demonstrated the feasibility of predicting florfenicol concentrations in the edible tissues of crucian carp using a route‐to‐route extrapolation method. 相似文献
993.
Meg D. Sislak Kathy A. Spaulding Debra L. Zoran John E. Bauer James A. Thompson 《Veterinary radiology & ultrasound》2014,55(2):195-201
Echoes are frequently seen in the urinary bladder of cats during abdominal ultrasound. These have been attributed to hematuria, pyuria, crystalluria, and lipid. However, sonographic findings have not been previously correlated with urinalysis. We prospectively evaluated 40 clinically normal cats via ultrasound, serum chemistry, and urinalysis. Thin layer chromatography was performed on the urine to determine the amount (mg) of lipid subfractions including diacylglycerol, triglyceride, phospholipid, free fatty acid, cholesterol, and cholesterol ester. Ninety percent (36/40) of the cats in our population had sonographic echoes suspended in the urinary bladder, with most having a subjective score of mild echoes (n = 20). None of the sonographic echoes were gravity dependent or caused distal acoustic shadowing, reverberation, or twinkle artifact. Of the cats with sonographic echoes in the urine, 66% (24/36) had no significant findings on urinalysis other than the presence of lipid. The total amount of subjective sonographic echoes was not significantly related to the total amount of fat measured on thin layer chromatography or the number of lipid droplets seen on urinalysis. An increased amount of urine diacylglycerol was significantly associated with clumping of echoes (P = 0.02) and the amount of lipid droplets seen on urinalysis (P = 0.04). An association between increased amounts of urine diacylglycerol and the amount of echoes seen on ultrasound approached significance (P = 0.05). Findings from this study support previously published theories that sonographic echoes within the urinary bladder of clinically normal cats may be due to urine lipid. 相似文献
994.
995.
H.S. Cameron D.V.M. Ph.D. 《New Zealand veterinary journal》2013,61(3):41-44
Extract First let me express my appreciation of being the recipient of a Fulbright Fellowship for research in New Zealand and also for the privilege of discussing brucellosis before the New Zealand Veterinary Association. 相似文献
996.
R.E. Harris B.A. B.Sc. Ph.D. M.R.C.V.S. W.A.G. Charleston B.V.Sc. Ph.D. M.R.C.V.S. M.A.C.V.Sc. 《New Zealand veterinary journal》2013,61(1-2):11-17
Extract From time to time, interest is shown in the use of licks for providing anthelmintic medication to livestock. This paper presents results from two trials on the use, with sheep, of a solidified molasses block incorporating phenothiazine and thiabendazole. 相似文献
997.
Extract Whenever disease is discussed in terms of beef production, in New Zealand it is certain to include infertility (brucellosis, vibriosis), metabolic diseases (bloat, staggers) and possibly exotic diseases and their prevention. On the rare occasion that parasitism is considered it tends somehow to find itself, along with selenium and other deficiency diseases, under a general heading of nutrition or management. This is probably because, while parasitism is still recognized as an infectious disease with clear clinical signs in severe cases, the tendency is to ignore its presence unless nutritional or management changes force a confrontation. 相似文献
998.
999.
Evaluation of a screening programme for identification of mannosidosis heterozygotes in angus cattle
R.D. Jolly B.V.Sc Ph.D. M.A.C.V.Sc. K.G. Thompson B.V.Sc C.A. Tse B.Sc. 《New Zealand veterinary journal》2013,61(10):185-190
Sir, — In recent years, much research effort has been directed towards identifying the cause of Ryegrass staggers (RGS). Many promising leads have been investigated, including studies of fungi in soil, ryegrass leaves, and dead leaf litter that could produce tremorgenic mycotoxins(3). Several groups of fungi produce tremorgens(4) which, when injected into sheep, produce symptoms similar to those in field outbreaks of RGS. However, under field conditions, populations of these fungi have not been shown to differ significantly between toxic and non-toxic pasture(7) (McKenzie &; Byford, unpublished data). 相似文献
1000.
J. A. Cadwallader B.V.Sc. D.V.C.S. M.A.C.V.Sc. B.Sc. M. R. Alley B.V.Sc. 《New Zealand veterinary journal》2013,61(9):207-211
Abstract Extract Malignant hyperthermia is a rare and usually fatal complication of general anaesthesia. It occurs in man (Britt and Kalow, 1970) and in certain breeds of pigs, the, Landrace (Hall et al., 1966; Berman et at, 1970; Harrison et al., 1970) the Poland China (Jones et al., 1972), the Pietrain (Allen et al., 1970) and the Large White (Mawdesley-Thomas, 1969). 相似文献