Isolated fracture of the radial diaphysis in dogs

Four cases of isolated fracture of the radial diaphysis were diagnosed. All cases were successfully managed conservatively. Direct trauma was not a feature in any of the cases. The history, presenting signs and fracture morphology in each case were similar suggesting a common aetiology. The case histories are reviewed and a possible aetiology discussed.     

Prevalence and risk factors in serous arthritis in the carpal joint of Norwegian coldblooded trotters

Of 508 four-year-old coldblooded trotters examined for carpitis, 135 (27%) had the condition. Thirty horses had unilateral carpitis on the left frontlimb, 52 on the right frontlimb and 53 had bilateral carpitis. Of these horses, 105 were stallions, 135 were geldings and 269 were mares. The prevalence of carpitis in these three groups was 25%, 25% and 28%, respectively.Information was obtained on the training regimes in four periods of the life of 378 horses. The odds ratios for the training variables were of the same order in all four periods. In logistic regression analyses on the training variables for the first period for the variable percentage of carpitis within each progeny group (sire index), the odds ratio corresponding to a 10% increase in sire index was 1.7 (1.4, 2.1) (95% confidence interval of the odds ratio). The odds ratios for leaving the horses out in a paddock, walking in a jogcart and fast training, or not in each case, were 0.4 (0.2, 0.9), 2.5 (1.2, 5.3) and 2.0 (0.9, 4.4), respectively. This implies a decreased risk of developing carpitis for horses left out in a paddock as a two-year-old, and a 2.5 and 2.0 times increased risk of carpitis occuring in horses exposed to walking in a jogcart and fast training, respectively.Information on the feeding regimes during the first, second and third year collected by a questionnaire revealed no association with carpitis beyond that which could be ascribed to chance. The rations offered were within normal ranges except for calcium, which was below recommended levels.     

Ocular lesions associated with coccidioidomycosis in dogs: 35 cases (1980-1985)

Thirty-five dogs with ocular lesions associated with coccidioidomycosis were examined. Serologic and/or histologic evaluation confirmed the diagnoses of coccidioidomycosis. The disease most frequently associated with signs referable to the anterior segment of the eye, such as iritis and granulomatous uveitis. Histologic evaluation of the eye revealed a primary posterior segment disease, such as chorioretinitis or retinal separation, with an extension into the anterior segment of the eye.     

Bovine postparturient hemoglobinemia: hypophosphatemia and metabolic disorder in red blood cells

Mechanism of hemolysis in postparturient hemoglobinemia was studied in 7 cows. Cows 1 to 5 had a history of hemoglobinemia at a previous calving, but hemoglobinemia did not occur during the present parturition. Cow 6, a daughter of cow 4, and cow 7 from another farm, developed postparturient hemoglobinemia and had hemoglobinuria on days 20 and 21 and 10 to 17 after calving, respectively. During the time cows 6 and 7 had hemoglobinuria, both cows had a marked decrease in serum inorganic phosphorus, RBC adenosine 5'-triphosphate (ATP), and reduced glutathione, and a significant (P less than 0.01) increase in methemoglobin concentration. In cow 6, these changes were observed before the onset of hemoglobinuria, indicating metabolic disorder of RBC. After phosphate administration IV, serum inorganic phosphorus was corrected, and RBC ATP was increased above base-line value. During the time cows 6 and 7 had hemoglobinuria, PCV, hemoglobin concentration, and RBC count decreased progressively and reached nadir values, 40% to 50% of baseline values, on day 22 in cow 6 and on day 19 in cow 7. Cows 6 and 7 were anemic, even after serum inorganic phosphorus and RBC ATP values returned to acceptable values. Glycolytic disorder and depletion of ATP, resulting from phosphorus deficiency, appeared to be a primary and essential step leading to hemolysis in postparturient hemoglobinemia in cows 6 and 7.     

Recovery from severe hydroureter and hydronephrosis after ureteral anastomosis in a dog

Progressive hydroureter and hydronephrosis were diagnosed in a dog after anastomosis of a crushed ureter. Nephrectomy was averted when partial resolution was noticed one month after the ureteral repair. The appearance of the kidney and ureter was nearly normal several months later. Conservative management should be considered in cases of partial unilateral ureteral obstruction.     

Effect of photoperiod and temperature on prolactin secretion in ovariectomized gilts

Five ovariectomized (OVX) gilts were placed in each of two chambers at 20 C with a photoperiod of 12 h light and 12 h dark for 8 d (12L:12D). On d 1, blood samples were collected via jugular cannula every 30 min from 0830 to 1630. At 1630, 200 micrograms of thyrotropin releasing hormone (TRH) were injected iv and blood samples taken every 10 min for 1 h and every 30 min for the next 2 h. On d 2, samples were taken every 30 min from 0830 to 0930 and from 1530 to 1630. Temperature was changed to 10 C or 30 C on d 3. Samples were taken from 0830 to 1630 on d 3, 4 and 9. At 1630 on d 9, the TRH challenge was repeated. Mean basal serum concentrations of prolactin (PRL) were similar for all gilts and for all periods. However, serum PRL response (ng PRL X ml-1 X 150 min-1) to TRH increased (P less than .0001) after exposure to 30 C, while exposure to 10 C failed to alter PRL response. In Exp. 2, six ovariectomized gilts were assigned to each chamber. The protocol of Exp. 1 was followed through d 3, except temperature and photoperiod were changed to 10 C and 8L:16D or 30 C and 16L:8D. On d 34 the TRH challenge was repeated. Mean basal serum concentration of PRL was similar for all gilts and all periods. However, simultaneous increases in temperature and photoperiod increased (P less than .005) serum PRL response to TRH, whereas simultaneous decreases in temperature and photoperiod failed to alter PRL response to TRH.     

The effects of undernutrition of suckled pigs on subsequent growth and body composition after nutritional rehabilitation

The effect of nutritional restriction and rehabilitation imposed between 5 and 35 d and 35 and 166 d of age, respectively, on body and tissue growth were investigated in 96 Yorkshire pigs from 12 litters. One-half of the pigs were allowed to suckle continuously until weaning (fully fed, FF); the remainder were removed from the sow for 16 h of each 24 h period (1600 to 0800 h), during which time they received only water (restricted feeding, RF). All pigs were fed ad libitum from 35 d of age. Although significantly lower body and tissue (liver, kidney and gastrocnemius muscle) weights were observed in the RF pigs at 35 and 70 d of age, by 166 d, because of compensatory growth between 35 and 166 d, the difference in body and muscle weights between the two groups of pigs (RF and FF) was reduced to 5%, but the difference in kidney and liver weight remained as high as 15 and 9%, respectively. Total DNA, RNA and protein in the tissues examined were also lower in the RF pigs at 35 and 70 d of age, but increased after ad libitum feeding to more than 90% of the corresponding value in the FF pigs by the time they reached 166 d of age. The results of these measurements and the comparison of the protein: DNA ratios of the tissues indicated that growth retardation in the RF pigs was associated with reduced cell proliferation in liver and kidney and nuclear proliferation in muscle rather than any decrease in cell (or fiber) volume. Percentage of fat was lower while percentage of protein was higher (on a dry matter basis) in the RF pigs than in the FF pigs at 35 d of age. No significant difference in fat and protein content in the carcasses between the RF and FF pigs at 70 or 166 d of age or 90 kg body weight was noted. The carcass of intact males had more protein and less fat than that of females.     

Maternal antibody and its effect on infectious bursal disease immunization

Chickens vaccinated with infectious bursal disease virus (IBDV) early in life and revaccinated with an inactivated, oil-adjuvant IBDV vaccine at 18 weeks of age produced and maintained high levels of virus-neutralizing (VN) antibody through 10 months of lay. VN-antibody titers of chicks hatched from eggs laid during the same period closely matched the average VN-antibody titers of the dams. A sequential study of the decline rates of IBDV maternal antibody (MAB) in unvaccinated and IBDV-vaccinated chicks showed that the vaccine virus did not accelerate the antibody depletion rate in vaccinated chicks. Chicks carrying high IBDV MAB showed no active immune response to vaccination with commercial IBDV vaccines. They were also refractory to a pathogenic field isolate of IBDV (FV). However, chicks with low levels of MAB responded to both vaccine virus and the FV, although their response to vaccine virus was milder and delayed.