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61.
Yigalelad Y. Ben-Yephet Michal Reuven L Mor Shulamit Manulis C. Shoham G. Forer M. J. Berlinger Lea Bar Nir D. Wool S. Cohen D. Veierov N. Aharonson Annie Fenigstein A. R. Horowitz N. C. Toscano D. Gerung Pnina Rapid D. Gerling Shalom W. Applebaum M. Klein B. Raccah R. G. Kenneth 《Phytoparasitica》1989,17(3):223-236
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Yuval Ramot Michal Steiner Yossi Lavie Nati Ezov Orgad Laub Eran Cohen Yotam Schwartz Abraham Nyska 《Journal of toxicologic pathology》2021,34(4):319
Bleeding during surgical procedures is a common complication. Therefore, hemostatic agents have been developed to control bleeding, and fibrin sealants have several benefits. sFilm-FS is a novel fibrin sealant that comprises a biodegradable co-polymeric film embedded with human fibrinogen and thrombin. Herein, the safety and efficacy of sFilm-FS were compared using a liver and spleen puncture model of Göttingen minipigs with those of the standard hemostatic techniques (control animals) and EVARREST®, a reference fibrin sealant. Hemostasis and reduced blood loss were more effectively achieved with sFilm-FS than with the standard techniques in the control animals and comparable to those achieved with EVARREST®. No treatment-related adverse effects were observed in any of the groups. Histopathological evaluation indicated that sFilm-FS was slightly and moderately reactive at the liver puncture site and spleen, respectively, compared with the standard techniques in the control animals. These changes are expected degradation reactions of the co-polymeric film and are not considered as adverse events. No treatment-related abnormalities were noted in the other evaluated organs. Additionally, no evidence of local or systemic thromboses was noted. These results support the use of sFilm-FS for hemostasis in humans. 相似文献
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Bates JK Bradley JP Teetsov A Bradley CR Ten Brink MB 《Science (New York, N.Y.)》1992,256(5057):649-651
Insoluble plutonium- and americium-bearing colloidal particles formed during simulated weathering of a high-level nuclear waste glass. Nearly 100 percent of the total plutonium and americium in test ground water was concentrated in these submicrometer particles. These results indicate that models of actinide mobility and repository integrity, which assume complete solubility of actinides in ground water, underestimate the potential for radionuclide release into the environment. A colloid-trapping mechanism may be necessary for a waste repository to meet long-term performance specifications. 相似文献
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P.H.F. Hobbelen P.J. van den Brink C.A.M. van Gestel 《Soil biology & biochemistry》2006,38(7):1596-1607
The aim of this study was to determine the effects of heavy metal pollution on the structure and functioning of detritivore soil communities that consist of isopods, millipedes and earthworms, in 15 heavily polluted flood plain soils, located in the delta area of the rivers Rhine and Meuse, in the Netherlands. The 15 study sites represent a gradient in Zn, Cu and Cd concentrations. The structural attributes of the detritivore community, which were assessed, were the species richness and densities in the field sites. The functioning of the detritivore community was studied by determining organic matter decomposition using litter bags and feeding activity with the bait-lamina method. Concentrations of Cd, Cu and Zn were measured in soil, pore water and 0.01 M CaCl2 extracts of the soil, in adult earthworms and plant leaves. Results show that metal pollution is not a dominating factor determining the species richness and densities of the selected detritivore groups, although the biomass of the earthworm Lumbricus rubellus was positively and significantly correlated to Zn concentrations in pore water and 0.01 M CaCl2 extracts. Litter decomposition was significantly and positively correlated to detritivore biomass and 0.01 M CaCl2 extractable Cd concentrations in soil and negatively to pH-CaCl2, although the range of pH values was very small. It can be concluded that in spite of high metal levels in the soil, bioavailable concentrations are too low to result in clear negative effects on the structure and functioning of detritivores in the Biesbosch, the Netherlands. 相似文献