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71.
通过相应膦二氯化物与2,4,6-三叔丁基苯基氨基锂的反应,再经1,8-二氮双环「5.4.0」-7-十一烯脱氯化氢合成了两个新的氮杂磷烯化合物。与二磷烯比较,分析了它们在核磁共振磷谱中化学位移的变化。 相似文献
72.
Satoshi Watanabe Satoshi Katayama Masashi Kodama Naritoshi Cho Kaoru Nakata Masaaki Fukuda 《Fisheries Science》2009,75(4):937-945
The relative contribution of particulate organic matters (POMs) in water column and sediment as a food source for the Manila
clam, Ruditapes philippinarum, was studied using carbon and nitrogen stable isotopic method (δ13C and δ15N) in a tidal flat at Seaside Park, Yokohama, Japan. Comparisons of δ13C and δ15N among R. philippinarum and POMs in surface water, bottom water, and sediment surface indicated that R. philippinarum larger than 5 mm shell length (SL) mainly assimilated benthic POM, and individuals smaller than 5 mm SL assimilated benthic
and pelagic POM. Continuous measurements of chlorophyll concentrations in the bottom water revealed tide-driven resuspension
of the benthic phytopigments. R. philippinarum showed differences in δ13C and δ15N along an inshore–offshore transect, indicating small-scale spatial differences in POM provision in the tidal flat. These
findings suggest that POM in the bottom water, supposedly inhaled by R. philippinarum, is a mixture of a larger proportion of resuspended benthic POM and a smaller proportion of pelagic POM, and that the mixing
ratio of the POMs may be affected by the hydrodynamics of flooding water associated with tidal flat topography. 相似文献
73.
Keita Kodama Masaaki Oyama Jeong-Hoon Lee Yoshiaki Akaba Yoshihiro Tajima Takamichi Shimizu Hiroaki Shiraishi Toshihiro Horiguchi 《Fisheries Science》2009,75(4):875-886
To explore which lifestages affect the stock size of young-of-the-year mantis shrimp Oratosquilla oratoria in Tokyo Bay, Japan, we investigated interannual variations in the quantitative relationships among egg production, larval
density, and juvenile density. We collected adult females, larvae, and juveniles during monthly field surveys from 2004 to
2007. The interannual trend for the juvenile density index differed from those for egg production and larval density; although
indices of both egg production and larval density were high in 2004 and 2007, the juvenile density index was high only in
2007, suggesting high mortality during the pelagic larval stage or the early phase of the postsettlement juvenile stage in
2004. We found that larval settlement started at the end of August and peaked in October, although larvae from the early spawning
season (May–June) should have settled in August or earlier. Juveniles were found throughout the bay except in areas where
bottom hypoxia occurred, suggesting that hypoxia restricts the spatial distribution of juveniles. Our results suggest that
mortality during the early life history fluctuates among years, probably because of changes in environmental conditions in
the bay, resulting in interannual variation in the stock size of young-of-the-year juvenile O. oratoria. 相似文献
74.
Akiko CHIBA Kaoru HATATE Rurika ONOMI Chiho KAWASHIMA Masaaki HANADA Tomoe MORIYAMA Akira GOTO Norio YAMAGISHI 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2020,82(11):1643
This study investigated consecutive fluctuations in serum activities of bone-specific alkaline phosphatase (ALP) isoenzyme 3 (ALP3) in 11 clinically healthy Holstein heifers during the first 18 months of life. ALP3 activities at the first sampling time point after weaning (3 months) were significantly lower than those at multiple time points during the pre-weaning period. Those activities increased from a minimum at 3 months to a peak at 6 months during the post-weaning period. In the anthropometric data, daily body weight and wither height gains appeared to be below the public data at 4 months and 4–5 months, respectively. The data suggested that serum ALP3 activity can be used to monitor skeletal growth of heifers at weaning. 相似文献
75.
Masaaki Chiwa Tomotaka Uemura Kyoichi Otsuki Hiroshi Sakugawa 《Water, air, and soil pollution》2012,223(8):5473-5481
Nitrogenous air pollutants including nitrogen dioxide (NO2), nitric acid (HNO3), nitrate (NO 3 ? ), ammonia (NH3), ammonium (NH 4 + ), and nitrous acid (HONO) were characterized at an urban forested (UF) site in Hiroshima and at a suburban forested (SF) site in Fukuoka, western Japan, using an annular denuder system for 1?year from May 2006 to May 2007 to compare the concentrations and chemical species of atmospheric nitrogenous pollutants between UF and SF sites. The proximity of the urban area was reflected in higher NO2 concentrations at the UF site than at the SF site. NO2 was more oxidized at the SF site because it is farther from an urban area than the UF site, which was reflected in higher concentrations of HNO3 at the SF site than the UF site. HNO3 and acidic sulfate is neutralized by NH3, existing as ammonium nitrate (NH4NO3) and ammonium sulfate [(NH4)2SO4] at the UF site. At the SF site, acidic sulfate is neutralized by NH3, existing as (NH4)2SO4, but NH4NO3, had scarcely formed at the SF site. A much higher HONO concentration was observed at the UF site than at the SF site, especially in winter and spring at night, which could be explained by higher NO2 concentrations at the UF site because of its proximity to an urban area and stagnant meteorological conditions. Atmospheric HONO determination was critical in evaluating the possibility of damage to trees in UF areas. 相似文献
76.
77.
Asanuma F Miyata H Iwaki Y Kimura M Matsumoto K 《Journal of toxicologic pathology》2009,22(3):153-166
The aim of this study was to prove our hypothesis that adult rats with lowering of body weight gain, rats at 12 weeks of age as an example, are suitable for evaluation of myelotoxicity. Age-related differences between young rats (6-week-old study) and adult rats (12-week-old study) were analyzed in hematological examination values. The data of the young rats were reprinted from our previous report (Miyata et al., 2009) since our hypothesis was verified by comparison with that previous report. Several experimental groups were defined for the 12-week-old study as well as for the 6-week-old study; these included 5-fluorouracil (5-FU) treated groups receiving 12, 15 and 18 mg/kg/day (FU12, FU15 and FU18), pair-feeding groups (R12, R15 and R18 receiving the same amount of food as in the FU12, FU15 and FU18 groups, respectively) and a nontreated control group. Numerous hematologic and bone marrow parameters in the 5-FU treated groups were comparable to those in the corresponding pair-feeding groups in both age studies. Generally, the influences of undernutrition were more apparent in the young rats than in the adult rats. Histopathological examinations showed a decrease in hematopoiesis in the bone marrow in the 5-FU treated and pair-feeding groups. No apparent differences were observed in the decreased hematopoiesis between the 5-FU treated and pair-feeding groups in the 6-week-old study, but a difference between these groups was noted in the 12-week-old study; decreased hematopoiesis was more frequently noted in the 5-FU treated groups. These facts suggest that adult rats are more suitable than young rats for evaluation of 5-FU-induced myelotoxicity. 相似文献
78.
Wilson BD Ii M Park KW Suli A Sorensen LK Larrieu-Lahargue F Urness LD Suh W Asai J Kock GA Thorne T Silver M Thomas KR Chien CB Losordo DW Li DY 《Science (New York, N.Y.)》2006,313(5787):640-644
Axonal guidance and vascular patterning share several guidance cues, including proteins in the netrin family. We demonstrate that netrins stimulate proliferation, migration, and tube formation of human endothelial cells in vitro and that this stimulation is independent of known netrin receptors. Suppression of netrin1a messenger RNA in zebrafish inhibits vascular sprouting, implying a proangiogenic role for netrins during vertebrate development. We also show that netrins accelerate neovascularization in an in vivo model of ischemia and that they reverse neuropathy and vasculopathy in a diabetic murine model. We propose that the attractive vascular and neural guidance functions of netrins offer a unique therapeutic potential. 相似文献
79.
Sugiyama H Akazome Y Shoji T Yamaguchi A Yasue M Kanda T Ohtake Y 《Journal of agricultural and food chemistry》2007,55(11):4604-4609
Inhibitory effects of apple polyphenol extract (AP) and procyanidin contained in AP on in vitro pancreatic lipase activity and in vivo triglyceride absorption in mice and humans were examined. AP and procyanidin considerably inhibited in vitro pancreatic lipase activity. However, polyphenols, except for procyanidin, in AP (i.e., catechins, chalcones, and phenol carboxylic acids) showed weak inhibitory activities on pancreatic lipase. Procyanidins separated by normal-phase chromatography according to the degree of polymerization were also examined. Inhibitory effects of procyanidins increased according to the degree of polymerization from dimer to pentamer. On the other hand, pentamer or greater procyanidins showed maximal inhibitory effects on pancreatic lipase. These results suggested that with respect to in vitro pancreatic lipase inhibition, the degree of polymerization was an important factor and oligomeric procyanidin mainly contributed. Next, we performed a triglyceride tolerance test in mice and humans. Simultaneous ingestion of AP and triglyceride significantly inhibited an increase of plasma triglyceride levels in both models. These results suggested that the oligomeric procyanidins contained in AP inhibited triglyceride absorption by inhibiting pancreatic lipase activity in mice and humans. 相似文献
80.
Katsuhiko Sumitomo Kenta Shirasawa Sachiko N. Isobe Hideki Hirakawa Akiho Harata Masato Kawabe Masafumi Yagi Masaaki Osaka Miyuki Kunihisa Fumiya Taniguchi 《Breeding Science》2021,71(2):261
White rust caused by Puccinia horiana Henn. adversely affects chrysanthemum (Chrysanthemum morifolium Ramat.) production. The breeding of resistant varieties is effective in controlling the disease. Here we aimed to develop DNA markers for the strong resistance to P. horiana. We conducted a linkage analysis based on the genome-wide association study (GWAS) method. We employed a biparental population for the GWAS, wherein the single nucleotide polymorphism (SNP) allele frequency could be predicted. The population was derived from crosses between a strong resistant “Southern Pegasus” and a susceptible line. The GWAS used simplex and double-simplex SNP markers selected out of SNP candidates mined from ddRAD-Seq data of an F1 biparental population. These F1 individuals segregated in a 1:1 ratio of resistant to susceptible. Twenty-one simplex SNPs were significantly associated with P. horiana resistance in “Southern Pegasus” and generated one linkage group. These results show the presence of a single resistance gene in “Southern Pegasus”. We identified the nearest SNP marker located 2.2 cM from P. horiana resistance locus and demonstrated this SNP marker-resistance link using an independent population. This is the first report of an effective DNA marker linked to a gene for P. horiana resistance in chrysanthemum. 相似文献