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排序方式: 共有106条查询结果,搜索用时 220 毫秒
101.
Banks JA Nishiyama T Hasebe M Bowman JL Gribskov M dePamphilis C Albert VA Aono N Aoyama T Ambrose BA Ashton NW Axtell MJ Barker E Barker MS Bennetzen JL Bonawitz ND Chapple C Cheng C Correa LG Dacre M DeBarry J Dreyer I Elias M Engstrom EM Estelle M Feng L Finet C Floyd SK Frommer WB Fujita T Gramzow L Gutensohn M Harholt J Hattori M Heyl A Hirai T Hiwatashi Y Ishikawa M Iwata M Karol KG Koehler B Kolukisaoglu U Kubo M Kurata T Lalonde S Li K Li Y Litt A Lyons E Manning G Maruyama T Michael TP 《Science (New York, N.Y.)》2011,332(6032):960-963
102.
Purification of a Low Molecular Weight Fucoidan for SPECT Molecular Imaging of Myocardial Infarction
Pierre Saboural Frédéric Chaubet Francois Rouzet Faisal Al-Shoukr Rana Ben Azzouna Nadia Bouchemal Luc Picton Liliane Louedec Murielle Maire Lydia Rolland Guy Potier Dominique Le Guludec Didier Letourneur Cédric Chauvierre 《Marine drugs》2014,12(9):4851-4867
Fucoidans constitute a large family of sulfated polysaccharides with several biochemical properties. A commercial fucoidan from brown algae, containing low molecular weight polysaccharidic species constituted of l-fucose, uronic acids and sulfate groups, was simply treated here with calcium acetate solution. This treatment led to a purified fraction with a yield of 45%. The physicochemical characterizations of the purified fucoidan using colorimetric assay, MALLS, dRI, FT-IR, NMR, exhibited molecular weight distributions and chemical profiles similar for both fucoidans whereas the sulfate and l-fucose contents increased by 16% and 71%, respectively. The biodistribution study in rat of both compounds labeled with 99mTc evidenced a predominant renal elimination of the purified fucoidan, but the crude fucoidan was mainly retained in liver and spleen. In rat myocardial ischemia-reperfusion, we then demonstrated the better efficiency of the purified fucoidan. This purified sulfated polysaccharide appears promising for the development of molecular imaging in acute coronary syndrome. 相似文献
103.
Isolation and identification of strawberry phenolics with antioxidant and human cancer cell antiproliferative properties 总被引:2,自引:0,他引:2
Zhang Y Seeram NP Lee R Feng L Heber D 《Journal of agricultural and food chemistry》2008,56(3):670-675
Studies suggest that consumption of berry fruits, including strawberries ( Fragaria x ananassa Duch.), may have beneficial effects against oxidative stress mediated diseases such as cancer. Berries contain multiple phenolic compounds, which are thought to contribute to their biological properties. Comprehensive profiling of phenolics from strawberries was previously reported using high-performance liquid chromatography with mass spectrometry (HPLC-MS) detection. The current study reports the isolation and structural characterization of 10 phenolic compounds from strawberry extracts using a combination of Amberlite XAD16-resin and C18 columns, HPLC-UV, and nuclear magnetic resonance (NMR) spectroscopy methods. The phenolics were cyanidin-3-glucoside ( 1), pelargonidin (2), pelargonidin-3-glucoside (3), pelargonidin-3-rutinoside (4), kaempferol (5), quercetin (6), kaempferol-3-(6'-coumaroyl)glucoside) (7), 3,4,5-trihydroxyphenyl-acrylic acid (8), glucose ester of ( E)- p-coumaric acid (9), and ellagic acid . Strawberry crude extracts and purified compounds 1- 10 were evaluated for antioxidant and human cancer cell antiproliferative activities by the Trolox equivalent antioxidant capacity (TEAC) and luminescent ATP cell viability assays, respectively. Among the pure compounds, the anthocyanins 1 (7156 microM Trolox/mg), 2 (4922 microM Trolox/mg), and 4 (5514 microM Trolox/mg) were the most potent antioxidants. Crude extracts (250 microg/mL) and pure compounds (100 microg/mL) inhibited the growth of human oral (CAL-27, KB), colon (HT29, HCT-116), and prostate (LNCaP, DU145) cancer cells with different sensitivities observed between cell lines. This study adds to the growing body of data supporting the bioactivities of berry fruit phenolics and their potential impact on human health. 相似文献
104.
Ariadna Giné Cristina González Lydia Serrano Francisco Javier Sorribas 《European journal of plant pathology / European Foundation for Plant Pathology》2017,148(4):795-805
The influence of the squash hybrid RS841 rootstock (Cucurbita maxima x C. moschata) on population dynamics of Meloidogyne incognita and yield of cucumber cv. Dasher II was assessed during 2013 and 2014 in a plastic greenhouse. In addition, the relationship between ecophysiological parameters (plant water status, gas exchange, and leaf reflectance) and Pi and cucumber yield were also estimated in 2013. Nematode densities were determined at the beginning (Pi) and at the end (Pf) of each crop, and the relationship between these parameters was used to estimate the maximum multiplication rate (a), the maximum population density (M) and the equilibrium density (E) per grafted and ungrafted cucumber and cropping season. Moreover, the relationship between the multiplication rate (Pf/Pi) and Pi was compared between grafted and ungrafted cucumber per cropping season. Finally, the relative yield of grafted or ungrafted cucumber was plotted against Pi to determine the tolerance limit (T) and the minimum relative yield (m) by the Seinhorst damage function model. Values of a, M and E in grafted cucumber were higher than in ungrafted one irrespective of the cropping season. These results were supported by comparing the relationship between Pf/Pi and Pi between grafted and ungrafted cucumber. The relationship between Pi and yield fitted the Seinhorst damage function. The values of T and m did not differ between grafted and ungrafted each year. Predawn water potential, net photosynthetic rate, and leaf chlorophyll index decreased with increasing Pi. In addition, relative yield was related to variation in net photosynthetic rate and the leaf chlorophyll index. Under the conditions of this study, RS841 rootstock was neither resistant nor tolerant to M. incognita. 相似文献
105.
106.
Lydia X. Gan Claudia L. Y. Tan Amirrudin B. Ahmad Yixiong Cai Darren C. J. Yeo 《水产资源保护:海洋与淡水生态系统》2023,33(1):89-101
- Commodity-driven forest conversion represents one of the most severe threats to freshwater biodiversity in Southeast Asia, notably causing population declines and the extinction of freshwater fish species.
- Although a variety of freshwater taxa are likely to be adversely affected by forest conversion, little is known about the impact on ecologically and economically important invertebrates such as decapod crustaceans.
- This study evaluated the impact of forest conversion and land-use change on freshwater Macrobrachium shrimp species, using species richness, abundance, and environmental data collected from 20 streams across southern Peninsular Malaysia. Streams were located in three types of landscape: forest; oil palm plantation; and mixed land use, comprising young secondary forest, small-scale plantations, patches of open and sparsely vegetated areas, and agricultural fields and clearings.
- Generalized linear models showed that even incomplete change from forest habitats to mixed land use and oil palm plantation resulted in significantly lower Macrobrachium native species richness and higher non-native species abundance. Native species richness was positively correlated with canopy cover, leaf litter, substrate size, and dissolved oxygen, and was negatively correlated with water temperature and conductivity. Native species richness was also negatively correlated with non-native species abundance, with non-native species abundance increasing along the human disturbance gradient.
- These results highlight the need for riparian habitat protection to conserve native Macrobrachium and limit the spread of non-native species. A management priority should be to maintain or restore optimum instream habitat conditions for shrimps, which would also benefit fish and other benthic macroinvertebrates. Suitable riparian management requires substantial support and funding from multiple stakeholders, but it can be aligned with other catchment-based strategies to optimize the use of limited resources available for freshwater biodiversity conservation.