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581.
D S Greco M E Peterson D Y Cho J E Markovits 《Journal of the American Veterinary Medical Association》1985,187(9):948-950
Juvenile-onset hypothyroidism was diagnosed in an adult mixed-breed dog examined because of quadraparesis. Unusual clinical signs attributable to juvenile-onset or congenital hypothyroidism included disproportionate dwarfism; enlarged, protruding tongue; mental dullness; and retention of a "puppy" coat, which was soft and fluffy, without guard hairs. Radiography of the vertebral column and long bones revealed multiple areas of delayed epiphyseal closure and epiphyseal dysgenesis. Myelography demonstrated several intervertebral disk protrusions in the cervical and lumbar regions. Hypothyroidism was confirmed on the basis of a low basal serum thyroxine concentration that failed to increase after the administration of thyroid stimulating hormone. Other laboratory abnormalities included nonregenerative, normocytic, normochromic anemia; mild hypercalcemia; and an impaired growth hormone (GH) secretory response after xylazine administration. At necropsy, the thyroid gland was small and weighed only 0.2g. Microscopic examination of the thyroid gland revealed a loss of glandular tissue, which was replaced by adipose tissue along its periphery. Gross or microscopic abnormalities were not noted in the pituitary gland, and immunohistochemical staining of the pituitary gland revealed a normal number of GH-containing acidophils. This suggests that primary hypothyroidism may result in an impaired secretion of growth hormone, and that pituitary dwarfism or GH deficiency may be difficult to differentiate from hypothyroid dwarfism on the basis of provocative GH testing alone. 相似文献
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Retinal dysplasia in American pit bull terriers – phenotypic characterization and breeding study
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585.
EVALUATION OF CONTRAST‐ENHANCED ULTRASONOGRAPHY AS A METHOD FOR DETECTING GALLBLADDER NECROSIS OR RUPTURE IN DOGS
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Paolo Bargellini Riccardo Orlandi Chiara Paloni Giuseppe Rubini Paolo Fonti Mark E. Peterson Mark Rishniw Cristiano Boiti 《Veterinary radiology & ultrasound》2016,57(6):611-620
Gall bladder necrosis and rupture are life‐threatening conditions in dogs requiring surgical intervention and early diagnosis is essential. Human patients with suspected gall bladder necrosis/rupture are commonly evaluated with contrast‐enhanced ultrasonography (CEUS), however this procedure has not been described in dogs with suspected gall bladder necrosis/rupture. In a prospective diagnostic cohort study, CEUS (using SonoVue contrast medium) was performed in 93 dogs with gallbladder lesions identified by abdominal conventional ultrasonography. Necrosis/rupture was identified by CEUS as a focal lack of enhancement of the gallbladder wall. Dogs with positive CEUS finding for necrosis/rupture (complete lack of regional wall enhancement) underwent immediate surgery as did dogs with other biliary disorders requiring surgery. Dogs with negative CEUS findings or those not requiring surgery were managed medically. In cases undergoing surgery, necrosis/rupture was confirmed intraoperatively (and via histopathology). Absence of necrosis/rupture was confirmed either intraoperatively (via histopathology) or was assumed to be absent by complete recovery with medical management. Forty‐nine dogs underwent surgery and cholecystectomy: 24 had necrosis/rupture. CEUS was more accurate (100% sensitive and specific) in diagnosing gallbladder wall necrosis/rupture than conventional ultrasonography (75% sensitive and 81% specific) (P < 0.03). In conclusion, CEUS provides accurate characterization of gallbladder wall integrity that can impact decisions regarding clinical management, either surgical or medical. 相似文献
586.
Jeffery B. Cannon Jeffrey Hepinstall-Cymerman Christopher M. Godfrey Chris J. Peterson 《Landscape Ecology》2016,31(9):2097-2114
Context
Landscape patterns created by natural disturbance such as windstorms can affect forest regeneration, carbon cycling, and other ecological processes.Objectives
We develop a method for remotely measuring tornado damage severity and describe landscape-scale patterns of tornado damage. We examine the extent and distribution of damage severity and gaps created by tornadoes, and examine how topographic variation can influence tornado damage severity.Methods
Focusing on two April 2011 tornadoes that struck the Chattahoochee National Forest (CNF) in Georgia and the Great Smoky Mountains (GSM) in Tennessee, we used supervised classification of aerial photographs to map damage severity. We report the extent and distribution of damage severity from each track and characterize patterns of damage using FragStats. Using topographic overlays, we test hypotheses regarding how physiographic features such as valleys and ridges affect tornado damage severity.Results
Tornado damage severity estimates were significantly correlated with ground-truth measurements. The 64-km CNF track damaged 1712 ha (>25 % severity), while the 26-km GSM track damaged 1407 ha. Tornado damage severity was extremely variable and frequency of gap sizes drastically decreased with size, with many small gaps and few very large gaps, consistent with other types of wind damage. Damage severity declined as tornadoes ascended ridges and increased as they descended ridges. This effect was more consistent on shallow slopes relative to steeper slopes.Conclusions
This study outlines an objective methodology for remotely characterizing tornado damage severity. The results from this study fill an important gap in ecological understanding of the spatial components of the forest tornado disturbance regime.587.
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Michael E Peterson 《Veterinary Clinics of North America: Exotic Animal Practice》2008,11(2):375-87, vii-viii
The purpose of this article is to familiarize the reader with the basic venom components, the pathophysiologic responses of envenomated dogs and cats, and some brief treatment guidelines for envenomations by various exotic "pets." Representative toxic species of reptiles, amphibians, and arthropods are included. The growing trend toward the collection of exotic animals by private owners increases the likelihood that veterinarians will face the challenge of treating an exotic envenomation. 相似文献
589.
Whereas the adrenal glands of healthy ferrets produce only limited amounts of androgenic steroids, adrenocortical neoplasms that arise in neutered ferrets typically secrete androgens or their derivative, estrogen. The 17,20-lyase activity of cytochrome P450 17alpha-hydroxylase/17,20-lyase (P450c17) must increase to permit androgen biosynthesis in neoplastic adrenal tissue. We screened ferret adrenocortical tumor specimens for expression of cytochrome b(5) (cyt b(5)), an allosteric regulator that selectively enhances the 17,20-lyase activity of P450c17. Cyt b(5) immunoreactivity was evident in 24 of 25 (96%) adrenocortical adenomas/carcinomas from ferrets with signs of ectopic sex steroid production. Normal adrenocortical cells lacked cyt b(5), which may account for the low production of adrenal androgens in healthy ferrets. Other markers characteristic of gonadal somatic cells, such as luteinizing hormone receptor, aromatase, and GATA4, were coexpressed with cyt b(5) in some of the tumors. We concluded that cyt b(5) is upregulated during gonadectomy-induced adrenocortical neoplasia and is a marker of androgen synthetic potential in these tumors. 相似文献
590.
Lara-Karena B. Kellogg Donald McKenzie David L. Peterson Amy E. Hessl 《Landscape Ecology》2008,23(2):227-240
Fire regimes are complex systems that represent an aggregate of spatial and temporal events whose statistical properties are
scale dependent. Despite the breadth of research regarding the spatial controls on fire regime variability, few datasets are
available with sufficient resolution to test spatially explicit hypotheses. We used a spatially distributed network of georeferenced
fire-scarred trees to investigate the spatial structure of fire occurrence at multiple scales. Mantel’s tests and geostatistical
analysis of fire-occurrence time series led to inferences about the mechanisms that generated spatial patterns of historical
fire synchrony (multiple trees recording fire in a single year) in eastern Washington, USA. The spatial autocorrelation structure
of historical fire regimes varied within and among sites, with clearer patterns in the complex rugged terrain of the Cascade
Range than in more open and rolling terrain further north and east. Results illustrate that the statistical spatial characteristics
of fire regimes change with landform characteristics within a forest type, suggesting that simple relationships between fire
frequency, fire synchrony, and forest type do not exist. Quantifying the spatial structures in fire occurrence associated
with topographic variation showed that fire regime variability depends on both landscape structure and the scale of measurement.
Spatially explicit fire-scar data open new possibilities for analysis and interpretation, potentially informing the design
and application of fire management on landscapes, including hazardous fuel treatments and the use of fire for ecosystem restoration.
相似文献
Donald McKenzieEmail: |