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211.
MacDonald KA Kittleson MD Garcia-Nolen T Larson RF Wisner ER 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2006,20(3):627-634
Cats with hypertrophic cardiomyopathy (HCM) often develop diastolic dysfunction, which can lead to development of left congestive heart failure. Tissue Doppler imaging (TDI) echocardiography has emerged as a useful, noninvasive method for assessing diastolic function in cats. Cardiac magnetic resonance imaging (cMRI) has been performed in cats and accurately quantifies left ventricular (LV) mass in normal cats. However, assessment of cardiac function in cats by cMRI has not been performed. Six normal Domestic Shorthair cats and 7 Maine Coon cats with moderate to severe HCM were sedated, and TDI of the lateral mitral annulus was performed. Peak early diastolic velocity (Em) was measured from 5 nonconsecutive beats. Cats were anesthetized with propofol and electrocardiogram-gated gradient echo cMRI was performed during apnea after hyperventilation. Short-axis images of the LV extending from the mitral annulus to the apex were obtained throughout the cardiac cycle. LV mass at end systole and LV volumes throughout the cardiac cycle were quantified according to Simpson's rule. To assess the possible influence of propofol on diastolic function, TDI was performed on the 7 cats with HCM while sedated and then while anesthetized with propofol. Em was significantly lower in cats with HCM than normal cats (6.7 +/- 1.3 cm/s versus 11.6 +/- 1.9 cm/s, P < .001, respectively). There was no difference in the cMRI indices of diastolic function in normal and HCM cats. Propofol did not reduce diastolic function (Em) in cats with HCM but mildly reduced systolic myocardial velocity (S) in Maine Coon cats with HCM that were anesthetized with propofol (P = .87 and P = .03, respectively). 相似文献
212.
MacDonald KA Kittleson MD Larson RF Kass P Klose T Wisner ER 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2006,20(5):1093-1105
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is the most common heart disease of cats, resulting in left ventricular (LV) hypertrophy, myocardial fibrosis, and diastolic dysfunction. HYPOTHESIS: Ramipril will reduce LV mass, improve diastolic function, and reduce myocardial fibrosis in cats with HCM without congestive heart failure (CHF). ANIMALS: This prospective, blinded, placebo-controlled study included 26 Maine Coon and Maine Coon cross-bred cats with familial HCM but without CHF. METHODS: Cats were matched for LV mass index (LVMI) and were randomized to receive ramipril (0.5 mg/kg) or placebo q24h for 1 year, with investigators blinded. Plasma brain natriuretic peptide (BNP) concentration, plasma aldosterone concentration, Doppler tissue imaging (DTI), and systolic blood pressure were measured at baseline and every 3 months for 1 year. Cardiac magnetic resonance imaging (cMRI) was performed to quantify LV mass and myocardial fibrosis by delayed enhancement (DE) cMRI at baseline and 6 and 12 months. Plasma angiotensin-converting enzyme (ACE) activity was measured on 16 cats 1 hour after PO administration. RESULTS: Plasma ACE activity was adequately suppressed (97%) in cats treated with ramipril. LV mass, LVMI, DTI, DE, blood pressure, plasma BNP, and plasma aldosterone were not different in cats treated with ramipril compared with placebo (P = .85, P = .94, P = .91, P = .89, P = .28, P = .18, and P = .25, respectively). CONCLUSION: Treatment of Maine Coon cats with HCM without CHF with ramipril did not change LV mass, improve diastolic function, alter DE, or alter plasma BNP or aldosterone concentrations in a relevant manner. 相似文献
213.
214.
As in many parts of the world, rural and forest-dependent communities in Ontario are struggling with a variety of economic
and demographic challenges. Ontario government ministries are seeking to enhance rural sustainable development while at the
same time maintaining forest habitat and preventing forest biodiversity decline. Commercial maple sugar bushes, which in Eastern
Ontario are typically family owned and operated, have the potential to play an important role in biodiversity conservation
and habitat protection, while at the same time contributing to sustainable development. Existing research has shown the social
and economic benefits of small scale maple sugar bushes, but room remains for greater study of the environmental impacts,
particularly in terms of forest biodiversity. In this study, woodlot management practices on twenty-two sugar bushes in Eastern
Ontario were compared against established forest biodiversity conservation guidelines, using information obtained through
detailed interviews with operators. Sugar bush operators reported the presence of many important habitats on their properties.
The interview results show that many standard sugar bush management practices are consistent with biodiversity conservation
principles. Operators were found to be receptive to biodiversity conservation ideals, and could enhance their contribution
to the provincial government’s official biodiversity strategy with additional guidance, incentives, and formal planning. The
findings suggest that through sound management and planning, small scale commercial sugar bush operations generally can be
made environmentally sustainable, and become important components in broader rural development strategies. 相似文献
215.
Steinmetz A Ellenberger K März I Ludewig E Oechtering G 《Journal of the American Animal Hospital Association》2012,48(1):66-70
A 7 yr old mixed-breed dog was presented with a choroidal melanoma of the left eye that had penetrated the sclera, producing an orbital mass. Bradycardia was detected on auscultation. The bradycardia resolved after exenteration of the orbit and was therefore presumed to be associated with the oculocardiac reflex. 相似文献
216.
Data on weed species currently found in winter oilseed rape, the extent of their occurrence and regional distinctions were collected in autumn 2005 and 2006 from a total of 978 rape fields throughout Germany. Investigations took place on untreated sites at the six to eight leaf stage of rape. Weed frequencies and densities were determined by randomly placing a 0.1?m2 quadrate frame ten times in each plot, identifying and counting all plants within the frame. Two year results are presented here with a main focus on regional distinctions in total weed infestation, species richness as well as differences in frequencies and densities of selected weed species between the federal states. As expected, the majority of weed species occurring in winter oilseed rape is not evenly spread over Germany. On the on hand there are weeds with a more or less limited distribution which can be frequently found in some regions but are absent in others while on the other hand several ubiquitous weed species mainly show regional differences in their densities. Sisymbrium officinale, Descurainia sophia, Centaurea cyanus, Anchusa sp., Sonchus sp., Rumex sp. or Euphorbia sp. are some of the weed species of mostly regional importance. In contrast statistically proofed differences in weed densities in the federal states of Germany were recorded for Capsella bursa-pastoris, Chenopodium album, Galium aparine, Lamium sp., Matricaria sp., Stellaria media, Thlaspi arvense, Veronica sp. and Viola arvensis. Total weed infestation level and the mean number of species per site also differed between the federal states of Germany. 相似文献
217.
Dissemination of small ruminant lentivirus (SRLV) infections in Norway is affected by the different control strategies used for maedi-visna virus (MVV) infections in sheep and caprine arthritis-encephalitis virus (CAEV) infections in goats. Here we investigated SRLV phylogenetic group variants in sheep. CAEV-like isolates, belonging to phylogenetic group C, were found among both seropositive sheep and goats in mixed flocks, in which sheep and goats are kept together. Intra-herd clustering confirmed that mixed flock animals were infected by the same virus variant, suggesting ongoing interspecies transmission. Few sheep flocks were found to be infected with the MVV-like phylogenetic group A. The apparent absence of SRLV group A type in goats is probably due to the MVV control programme and animal management practices. SRLV group C targets lungs and mammary glands in sheep, and induces typical SRLV pathological lesions. SRLV group C isolated from the sheep mammary glands suggested a productive infection and potential for transmission to offspring. SRLV group C was most prevalent among goats. A lower PCR sensitivity in seropositive sheep suggested a lower load of SRLV group C provirus in sheep than in goats. Higher genetic divergence of group C than in other SRLV groups and extensive heterogeneity among group C isolates in the matrix C-terminal region demonstrate the need for identifying conserved target regions when developing PCR protocols for SRLV detection. As sheep and goats may serve as reservoirs for all SRLV genogroup types, successful control programmes require inclusion of both species. 相似文献
218.
Use of a portable real-time reverse transcriptase-polymerase chain reaction assay for rapid detection of foot-and-mouth disease virus 总被引:13,自引:0,他引:13
219.
Silke Pfitzer Leith Meyer Liesel Laubscher Kristin Warren Rebecca Vaughan-Higgins Jacobus P. Raath Michael Laurence 《Veterinary anaesthesia and analgesia》2021,48(1):42-52
ObjectiveTo determine the cardiopulmonary effects of etorphine and thiafentanil for immobilization of blesbok.Study designBlinded, randomized, two-way crossover study.AnimalsA group of eight adult female blesbok.MethodsAnimals were immobilized twice, once with etorphine (0.09 mg kg–1) and once with thiafentanil (0.09 mg kg–1) administered intramuscularly by dart. Immobilization quality was assessed and analysed by Wilcoxon signed-rank test. Time to final recumbency was compared between treatments by one-way analysis of variance. Cardiopulmonary effects including respiratory rate (?R), arterial blood pressures and arterial blood gases were measured. A linear mixed model was used to assess the effects of drug treatments over the 40 minute immobilization period. Significant differences between treatments, for treatment over time as well as effect of treatment by time on the variables, were analysed (p < 0.05).ResultsThere was no statistical difference (p = 0.186) between treatments for time to recumbency. The mean ?R was lower with etorphine (14 breaths minute–1) than with thiafentanil (19 breaths minute–1, p = 0.034). The overall mean PaCO2 was higher with etorphine [45 mmHg (6.0 kPa)] than with thiafentanil [41 mmHg (5.5 kPa), p = 0.025], whereas PaO2 was lower with etorphine [53 mmHg (7.1 kPa)] than with thiafentanil [64 mmHg (8.5 kPa), p < 0.001]. The systolic arterial pressure measured throughout all time points was higher with thiafentanil than with etorphine (p = 0.04). The difference varied from 30 mmHg at 20 minutes after recumbency to 14 mmHg (standard error difference 2.7 mmHg) at 40 minutes after recumbency. Mean and diastolic arterial pressures were significantly higher with thiafentanil at 20 and 25 minute measurement points only (p < 0.001).ConclusionsBoth drugs caused clinically relevant hypoxaemia; however, it was less severe with thiafentanil. Ventilation was adequate. Hypertension was greater and immobilization scores were lower with thiafentanil. 相似文献
220.