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排序方式: 共有247条查询结果,搜索用时 281 毫秒
41.
Hiroshi UENO Osamu YAMATO Takeshi SUGIURA Moeko KOHYAMA Akira YABUKI Kenjiro MIYOSHI Kazuya MATSUDA Tsuyoshi UCHIDE 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2016,78(1):91-95
A male Japanese domestic cat with retarded growth in Hokkaido, Japan, showed
progressive motor dysfunction, such as ataxia starting at 3 months of age and tremors,
visual disorder and seizure after 4 months of age. Finally, the cat died of neurological
deterioration at 9 months of age. Approximately half of the peripheral blood lymphocytes
had multiple abnormal vacuoles. Magnetic resonance imaging showed bisymmetrical
hyperintensity in the white matter of the parietal and occipital lobes in the forebrain on
T2-weighted and fluid-attenuated inversion recovery images, and mild encephalatrophy of
the olfactory bulbs and temporal lobes. The activity of lysosomal acid β-galactosidase in
leukocytes was negligible, resulting in the biochemical diagnosis of GM1 gangliosidosis.
Histologically, swollen neurons characterized by accumulation of pale, slightly granular
cytoplasmic materials were observed throughout the central nervous system. Dysmyelination
or demyelination and gemistocytic astrocytosis were observed in the white matter.
Ultrastructually, membranous cytoplasmic bodies were detected in the lysosomes of neurons.
However, genetic analysis did not identify the c.1448G>C mutation, which is the single
known mutation of feline GM1 gangliosidosis, suggesting that the cat was affected with a
new variant of the feline disease. 相似文献
42.
Satoshi Furukawa Naho Tsuji Seigo Hayashi Yusuke Kuroda Masayuki Kimura Chisato Hayakawa Kazuya Takeuchi Akihiko Sugiyama 《Journal of toxicologic pathology》2022,35(1):37
We investigated the morphological effects of testosterone on placental development in a rat model of polycystic ovarian syndrome (PCOS). Testosterone propionate (TP), which was subcutaneously administered to pregnant rats with 5 mg/animal from gestation day (GD) 14 to GD 18, induced a maternal weight reduction without mortality or clinical signs from GD 19 onwards. A decrease in fetal and placental weight, an increase in intrauterine growth retardation (IUGR) rates, and histological changes in the placenta were observed on GD 21 but not on GD15 or 17. Histopathologically, on GD 21, the trophoblast septa thickened, and the maternal sinusoids were narrowed in the labyrinth zone, resulting in a small placenta. Additionally, the placental weight, thickness, and histological morphology in the labyrinth zone on GD 21 in the TP-treated group were nearly identical to those on GD 17 in the control and TP-treated groups. Therefore, it was assumed that the testosterone-induced small placenta was induced in association with the developmental inhibition of the fetal part of the placentas from GD 17 onwards. 相似文献
43.
Interannual variations in abundance, timing of outmigration from rivers, growth rate and condition of juvenile chum salmon
(Oncorhynchus keta) were studied in the Nemuro Strait (eastern Hokkaido, Japan) during 1999–2002 to establish a possible relationship to zooplankton
abundance. The otolith microstructure of juveniles was examined each year in late June to determine their time and size at
sea entry (i.e., outmigration), and to estimate the early marine growth rates. Salmon outmigration peaked in mid- or late
May, which coincided, in three of the four study years, with the peak release of juveniles into rivers within the study area.
Abundance, growth rate and condition of fish were higher in 2001, when—compared to other years—smaller fish experienced higher
growth rates, coinciding with greater zooplankton abundance for that year. Our results suggest that high zooplankton abundance
positively influenced juvenile chum salmon growth and the condition of the fish during their early marine life despite their
small size at sea entry. 相似文献
44.
Akihiko Yatsu Tomowo Watanabe Junta Mori Kazuya Nagasawa Yukimasa Ishida Toshimi Meguro Yoshihiko Kamei & Yasunori Sakurai 《Fisheries Oceanography》2000,9(2):163-170
Variability in catch-per-unit-effort (CPUE) was examined for the autumn cohort of Ommastrephes bartramii collected with research driftnets during 1979–1998 along five longitudinal transects passing through the Subarctic, Transitional and Subtropical Domains in the North Pacific. CPUE was generally low during the period of intensive commercial driftnet fishing (1980–1992) and increased following the 1992 moratorium on the use of large-scale driftnets. However, CPUE levels were low for the cohorts hatched in 1992 and 1996 (captured in subsequent years owing to a one-year life of O. bartramii ) that experienced low sea surface temperatures from hatching to recruitment. Among similar-aged squid collected from 180° and 179°30'W in June, mantle lengths were significantly greater in 1997 than during 1995–96. These findings suggest that the driftnet fishery and sea surface temperatures from hatching to recruitment strongly affected stock abundance and possibly growth. 相似文献
45.
ABSTRACT: As a possible factor leading to the low recruitment level of sea urchins in kelp forests, the inhibitory effect of 2,4-dibromophenol (DBP) and 2,4,6-tribromophenol (TBP) released from the large perennial brown algae Ecklonia kurome and Eisenia bicyclis on survival and metamorphosis of eight-armed larvae of the sea urchin Strongylocentrotus nudus was examined. The percentage of larvae that underwent metamorphosis in filtered sea water after 1 h exposure to one-half dilution of saturated dibromomethane solution (∼60 ppm) as a chemical inducer reached approximately 100% after 1 h, while that in filtered sea water containing 1 ppm TBP was reduced to 73%. This was further reduced to less than 40% in the presence of 10 and 20 ppm TBP after 2 h. In filtered sea water containing 1 and 10 ppm DBP, the proportion of metamorphosed larvae was reduced markedly to 43 and 5% after 2 h, respectively. All larvae exposed to 50 ppm TBP and to 20 and 50 ppm DBP died after 1 h. These findings suggest that DBP is more toxic than TBP for sea urchin larvae, strongly inhibiting their metamorphosis. 相似文献
46.
A Kojima F Fujinami M Takeshita Y Minato T Yamamura K Imaizumi A Okaniwa 《Nippon juigaku zasshi. The Japanese journal of veterinary science》1990,52(1):145-154
Nine out of 19 newborn pups from 4 litters died or euthanatized on day 10 to 17 after birth in a specific-pathogen-free beagle colony which had been established by cesarean section and bottle-feeding. Necropsy showed congestion and edema of the lungs, congestion of the liver and splenomegaly, as well as many subcapsular petechiae and wedge-shaped areas of ecchymosis on the cut surface of the kidneys. A cytopathic agent isolated from the lungs, kidneys and liver was identified as a canine herpesvirus. The bitches in the animal house were seroconverted into positive for the isolate after the outbreak of the disease. Histopathological lesions in six cases were characterized by multiple necrosis and hemorrhage in various organs. In addition, fibrinoid necrosis was seen in the arterial walls in wedge-shaped necrotic areas of the kidneys. The outbreak appeared to be temporary, since the same disease has not occurred in the colony up to the present time. 相似文献
47.
This study aimed to reveal the effects of direct exposure to cold weather under grazing in winter (GW) on the health of Japanese Black beef cattle, as assessed using physiological, immunological, and behavioral parameters. Ten Japanese Black beef cattle (328 ± 45 kg, 7.6 ± 3.4 years of age) were used in this experiment. In winter, five of the 10 cattle grazed for 2 months in a 1.8 ha pasture (GW), and the remaining cattle were fed under confined conditions with tethering (control [CT]). The two groups were fed similar feed during the experiment, except for the grazing forage. Blood samples were collected approximately every 2 weeks. The numbers of neutrophils and monocytes and antioxidant enzyme activity were higher in the GW group than in the CT group (p < 0.05). The proportions of CD4‐single‐positive cells were lower in GW cattle than in CT cattle (p = 0.06). This study showed that direct exposure of beef cattle to cold weather under GW enhanced the levels of circulating neutrophils and monocytes and contributed to the kinetic homeostasis of lymphocytes but also activated antioxidant enzymes due to an increase in oxidative stress. 相似文献
48.
Yuri ABE Tomokazu TAMURA Shiho TORII Shiho WAKAMORI Makoto NAGAI Kazuya MITSUHASHI Junki MINE Yuri FUJIMOTO Naofumi NAGASHIMA Fumi YOSHINO Yukihiko SUGITA Takushi NOMURA Masatoshi OKAMATSU Hiroshi KIDA Yoshihiro SAKODA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2016,78(1):61-70
In our previous study, we genetically analyzed bovine viral diarrhea viruses (BVDVs)
isolated from 2000 to 2006 in Japan and reported that subgenotype 1b viruses were
predominant. In the present study, 766 BVDVs isolated from 2006 to 2014 in Hokkaido,
Japan, were genetically analyzed to understand recent epidemics. Phylogenetic analysis
based on nucleotide sequences of the 5′-untranslated region of viral genome revealed that
766 isolates were classified as genotype 1 (BVDV-1; 544 isolates) and genotype 2 (BVDV-2;
222). BVDV-1 isolates were further divided into BVDV-1a (93), 1b (371) and 1c (80)
subgenotypes, and all BVDV-2 isolates were grouped into BVDV-2a subgenotype (222). Further
comparative analysis was performed with BVDV-1a, 1b and 2a viruses isolated from 2001 to
2014. Phylogenetic analysis based on nucleotide sequences of the viral glycoprotein E2
gene, a major target of neutralizing antibodies, revealed that BVDV-1a, 1b and 2a isolates
were further classified into several clusters. Cross-neutralization tests showed that
BVDV-1b isolates were antigenically different from BVDV-1a isolates, and almost BVDV-1a,
1b and 2a isolates were antigenically similar among each subgenotype and each E2 cluster.
Taken together, BVDV-1b viruses are still predominant, and BVDV-2a viruses have increased
recently in Hokkaido, Japan. Field isolates of BVDV-1a, 1b and 2a show genetic diversity
on the E2 gene with antigenic conservation among each subgenotype during the last 14
years. 相似文献
49.
Software development for estimating the concentration of radioactive cesium in the skeletal muscles of cattle from blood samples
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Tomokazu Fukuda Masahiro Hiji Yasushi Kino Yasuyuki Abe Hideaki Yamashiro Jin Kobayashi Yoshinaka Shimizu Atsushi Takahashi Toshihiko Suzuki Mirei Chiba Kazuya Inoue Yoshikazu Kuwahara Motoko Morimoto Masafumi Katayama Kenichiro Donai Hisashi Shinoda Tsutomu Sekine Manabu Fukumoto Emiko Isogai 《Animal Science Journal》2016,87(6):842-847
The 2011 earthquake severely damaged the Fukushima Daiichi Nuclear Power Plant (FNPP), resulting in the release of large quantities of radioactive material into the environment. The deposition of these radionuclides in rice straw as livestock feed led to the circulation of contaminated beef in the market. Based on the safety concern of the consumers, a reliable method for estimating concentrations of radioactive cesium in muscle tissue is needed. In this study, we analyzed the concentrations of radioactive cesium in the blood and skeletal muscle of 88 cattle, and detected a linear correlation between them. We then developed software that can be used to estimate radioactive cesium concentrations in muscle tissue from blood samples. Distribution of this software to the livestock production field would allow us to easily identify high‐risk cattle, which would be beyond the safety regulation, before shipping out to the market. This software is planned to be released as freeware. This software would contribute to food safety, and aid the recovery of the livestock industry from the damage creacted by the 2011 Tohoku earthquake and tsunami. 相似文献
50.
The cumulative methane production from dairy cattle slurry can be explained by its volatile solid,temperature and length of storage
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Takuji Sawamoto Megumi Nakamura Kenji Nekomoto Shinji Hoshiba Keiko Minato Motoo Nakayama Takashi Osada 《Animal Science Journal》2016,87(6):827-834
In order to refine the national estimate of methane emission from stored cattle slurry, it is important to comprehend the basic characteristics of methane production. Two dairy cattle slurries were obtained from livestock farms located in Hokkaido (a northern island) and Kyushu (a southern island). The slurries were diluted with water into three levels: undiluted, three times diluted, and 10 times diluted. Three hundred mL of the slurries were put into a bottle with a headspace volume of 2.0 L, which was filled with nitrogen gas and then sealed by butyl rubber. Four levels of temperature were used for incubation: 35, 25, 15 and 5 °C. The time course of the cumulative methane production per volatile solid (VS) was satisfactorily expressed by an asymptotic regression model. The effect of dilution on the methane production per VS was not distinctive, but that of temperature was of primary importance. In particular, higher temperature yields a higher potential production and a shorter time when the cumulative production reaches half of the potential production. The inclusive and simple models obtained in this study indicate that the cumulative methane production from stored cattle slurry can be explained by VS, temperature and length of storage. 相似文献