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41.
OBJECTIVE: To quantify the effect on gap stiffness and cranial to caudal bending stiffness of conversion of the 6 distal clamps of planar bilateral fixator models to sliding clamps and the effect of attachment of composite beams to the sliding clamp models. STUDY DESIGN: Mdash;Mechanical testing performed on models. SAMPLE POPULATION: Five models using birch dowels and a commercially available external skeletal fixator system. METHODS: A segmentally comminuted, middiaphyseal fracture was simulated with the use of wooden dowels, and a bilateral 6-pin fixator was applied to create each of 5 models. The models were mechanically tested with all fixed clamps, with the 6 distal clamps converted to sliding clamps and with composite beams attached to the sliding clamp models. Testing was carried out in axial loading with physiologically relevant loads for a canine model, and in bending in the cranial to caudal plane. RESULTS: Sliding clamp fixators with composite beams attached exhibited a nonlinear increase in axial loading gap stiffness as load increased. The composite beam group also exhibited an increase in cranial to caudal bending stiffness as compared with fixed clamp and sliding clamp models. CONCLUSIONS: Using composite beam elements, planar bilateral external fixators can be constructed such that the fracture site would undergo controlled amounts of displacement at low loads and lessening displacement at higher loads. CLINICAL RELEVANCE: The nonlinear stiffness profile attained by the addition of composite beam elements to a planar external fixator allows controlled axial micromotion at the fracture site. Because controlled axial micromotion appears to stimulate fracture healing, a nonlinear stiffness profile of this type should enhance fracture healing.  相似文献   
42.
Investigations of 1167 dairy cows out of 105 herds with fertility disorders on secretion of Coxiella burnetii (C. burnetii) by the genitals as well as serological studies of these animals using ELISA demonstrated that C. burnetii infections are significantly associated with abortions but not with repeated inseminations without success or vaginal excretions. The demonstration of an increased risk of infections for persons caring for those dairy herds could be shown by a total of 253 serological studies. A comparison of these studies of farmers caring for dairy herds suffering from abortions a seroprevalence of > or = 20% showed that these persons revealed significantly more frequent antibodies against C. burnetii than farmers of the group compared with. Further studies showed that in herds suffering from abortions a seroprevalence of > or = 20% means an additional risk of infections of farmers. Vice versa abortions of the cows in herds with a seroprevalence of > or = 20% imply an additional infectious risk.  相似文献   
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Objective: To describe a case of confirmed baclofen intoxication in a dog that was successfully treated with hemodialysis and hemoperfusion (HD/HP) and to report the serum baclofen kinetics. Case summary: A 2.5‐year‐old, 23 kg, spayed female Brittany Spaniel‐mix was treated after ingesting 21‐52 mg/kg of baclofen. The dog was comatose and was receiving manual ventilation at the time of presentation. Extracorporeal HD/HP was started 10 hours after admission. Within 3 hours of starting HD/HP the dog began initiating breaths and was extubated 18 hours after admission. Serial serum samples that were obtained during the first 24 hours of hospitalization were later analyzed for baclofen concentrations. The dog had elevated creatine phosphokinase and liver enzymes that correlated with an agitated recovery period. The dog had thrombocytopenia that resolved by 10 days after presentation. New or unique information provided: HD/HP shortened the baclofen serum elimination half‐life from 5 to 1.5 hours in the initial 2 hours of treatment. The intrinsic elimination rate constant (Kintr) for this dog was 0.138/hour and the total elimination rate constant (Ktot) during the first 2 hours of HD/HP treatment was 0.458/hour. In this dog, HD/HP was an effective method for rapidly decreasing serum baclofen concentration after an acute overdose.  相似文献   
44.
ObjectivesThis study measured plasma atrial natriuretic peptide (ANP) concentration in horses with heart valve regurgitations (HVR) with and without atrial and ventricular dilatation.BackgroundIn humans and small animals, plasma ANP concentration is increased in heart disease and correlates with the severity of clinical signs and heart enlargement.Animals, materials and methodsTen healthy horses (control) and 36 horses with HVR were evaluated by auscultation, electrocardiography, echocardiography, and determination of plasma ANP.ResultsControl horses demonstrated mean plasma ANP concentration of 21 ± 5.4 pg/mL. Of the 36 horses with HVR, 17 horses possessed normal echocardiographic heart size (group 1), 10 horses had a left atrial dilatation (group 2) and 9 horses had both left atrial and ventricular dilatation (group 3). Mean plasma ANP concentration of groups 1, 2 and 3 was 20.1 ± 5.6 pg/mL, 22.9 ± 11.0 pg/mL and 27.6 ± 17.4 pg/mL, respectively. The plasma ANP concentrations of HVR and control horses were not significantly different. The highest ANP concentrations were observed in horses with atrial and ventricular dilatation. No correlation between left atrial or ventricular size, weight, or sex and the plasma ANP concentration was found.ConclusionsNo significant differences in plasma ANP concentration was observed between groups. Further study, especially in horses with clinical signs of heart failure is needed.  相似文献   
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The availability of public recreational facilities is being threatened by growing demands, limited supplies, and declining government funding. In response to these pressures, the economic potential of agroforestry for supplementing operating budgets of public recreational parks is examined in a case study park consisting of 324 hectares. Agroforestry enterprises native to the area were selected for development on 70 hectares of the site. Linear programming was used to determine the optimum combinations of 23 agroforestry regimes composed of the following activities: 1) conventional forestry planting, tree density of 1682 trees/hectare, 2) the selected agroforestry planting with hay, tree density of 1495 trees/hectare, 3) the selected agroforestry planting with grazing, 4) hay production, and 5) rental of pasture for grazing. The objective function of the study was to maximize the net present value of the study site subject to land, labor, capital, and minimum annual income constraints. The preferred optimal regime generated $1782 per hectare from an agroforestry planting configuration of 1495 trees/hectare with 75 percent hay, 25 percent grazing, and no annual income requirements. Minimum annual income requirements of $2400 and $4800 were feasible but suboptimal from a net present value criteria. The study found that agroforestry could be used to privatize selective activities of public recreational parks and thus enable public agencies to provide these facilities more effectively.  相似文献   
47.
    
Ohne Zusammenfassung  相似文献   
48.
Summary A testing procedure with a new and simple specimen shape is presented which is appropriate to characterize fracturing of inhomogeneous and complex materials like wood. With this, the fracture energy of spruce wood is determined in the TL and RL direction. The size effect, i.e. influences of specimen dimensions on KIC and Gf (specific fracture energy) are investigated. Stress and deformation distribution in the newly developed specimens are analysed with FE methods. The measured load-displacement curves are approximated by bilinear softening diagrams and FE analysis. Based on these results, it is tried to interpret typical deviations from LEFM's behaviour by mechanisms like microcracking, crack branching or crack tip bridging.The authors thank Dr. A. Teischinger for supplying the testing material and Dipl. Ing M. Elser for preparation of the diagrams. Financial support of the Fonds zur Förderung der wissenschaftlichen Forschung, Wien is gratefully acknowledged.  相似文献   
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Existing log grading procedures in the United States make only visual assessments of log quality. These procedures do not incorporate estimates of the modulus of elasticity (MOE) of logs. It is questionable whether the visual grading procedures currently used for logs adequately assess the potential quality of structural products manufactured from them, especially those for which MOE is of primary concern. The purpose of this study was to investigate the use of stress wave nondestructive evaluation techniques to sort red maple logs for the potential quality of lumber obtained from them. Ninety-five red maple logs were nondestructively evaluated using longitudinal stress wave techniques and sorted into four stress wave grades. The logs were then sawn into cants and lumber. The same procedure was used to obtain stress wave times in the cants and lumber. The lumber specimens were then dried and graded using a transverse vibration technique. The results of this study showed that good relationships existed between stress wave times measured in logs, cants, and the lumber produced from the logs. It was found that log stress wave grades have positive relationships with the lumber grades. Logs with high stress wave grades produced high-grade lumber. These findings indicate that the longitudinal stress wave technique has potential in sorting logs and cants for the production of high MOE products.The Forest Products Laboratory is maintained in cooperation with the University of Wisconsin. This article was written and prepared by U.S. Government employees on official time, and it is therefore in the public domain and not subject to copyright.  相似文献   
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