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181.
Liver pathology and immune response in experimental Fasciola hepatica infections of goats 总被引:1,自引:0,他引:1
Martínez-Moreno A Jiménez-Luque V Moreno T Redondo ES de las Mulas JM Pérez J 《Veterinary parasitology》1999,82(1):19-33
The relationship between the immune response and the pathogenesis of the disease was studied in different primary and secondary experimental Fasciola hepatica infections of goats. The establishment of the infection, measured as percentage of recovered flukes at the necropsy, was similar in primarily and secondarily infected animals (between 19.7% and 24.3%), but the hepatic damage was much more severe in secondarily infected goats, as revealed by the levels of serum hepatic enzymes GGT and LDH. Primary infection evolves to chronic fasciolosis that did not induce the development of resistance, since goats were highly susceptible to secondary infection, showing severe acute and chronic hepatic lesions that led to the death of some animals in each group. The immune response to the infection was proved by the production of specific IgG antibodies to ESP of F. hepatica and the involvement of CD3+ T lymphocytes and lambda IgG+ plasma cells in the hepatic infiltrate. Secondary infection did not induce any difference in either IgG response or in the cellular composition of the infiltrate of hepatic lesions, although this was much more extended. However, neither antibodies nor cell-mediated response were protective: there was no correlation between IgG levels and fluke burden and there was no evidence of cell-mediated killing of the parasite. This suggests the existence of some immune evasion mechanisms in goat infection with F. hepatica. The parasite may depress the local inflammatory and immune response, as suggested by the scarcity of CD3+ T cells in the infiltrate surrounding acute migratory tunnels. Moreover, in secondary infected goats can be suspected an immunological damage of the liver, since a very severe infiltrate of immune cells replaced wide areas of hepatic parenchyma and an immune-mediated damage of hepatocytes could occur. 相似文献
182.
A. Bertaccini J. Fránová S. Paltrinieri M. Martini M. Navrátil C. Lugaresi J. Nebesárová M. Simkova 《European journal of plant pathology / European Foundation for Plant Pathology》1999,105(5):487-493
During the summer 1996, twelve of twenty-eight leek plants located in a garden near eské Budjovice, South Bohemia exhibited symptoms typical of diseases associated with phytoplasmas. In summer 1998 similar symptoms were detected in leek plants in a field used for seed production located in Romagna, North Italy. In both cases the plants were established in the spring of the previous year. Plants showed flower abnormalities: stamen elongation, anther sterility, pistil proliferation, as well as poor, if any, seed production. Phytoplasma-like structures were detected by scanning and transmission electron microscopy in phloem sieve elements in the Czech diseased plants, but not in healthy ones. Nested-PCR amplifications of extracted DNA with phytoplasma-specific oligonucleotide primer pairs confirmed the presence of phytoplasmas in these plants at low concentrations. Restriction fragment length polymorphism analyses of amplified ribosomal sequences allowed the identification of detected phytoplasmas: all the samples from the Czech Republic contained aster yellows related phytoplasmas (16SrI-B) while in the Italian samples aster yellows related phytoplasmas (16SrI-B) together with stolbur related phytoplasmas (16SrXII-A) were identified. This is the first report of detection and identification of a phytoplasma disease of leek in the Czech Republic and Italy. 相似文献
183.
Simón MC Ortega C Alonso JL Gironés O Muzquiz JL García J 《The Veterinary record》1999,144(11):287-291
The prevalence and risk factors associated with leptospirosis were studied in veterinary students in Zaragoza. Sera were collected at the beginning and end of the academic year 1994 to 1995 and were tested by ELISA against a pool of Leptospira interrogans serovars bratislava, canicola, grippotyphosa, hardjo, icterohaemorrhagiae and pomona antigens. At the beginning of the study the prevalence was 8.14 per cent and at the end it was 11.4 per cent. The incidence of the disease during the study was 0.0394. Risk factors associated with leptospirosis included: taking the course specialising in food inspection and technology, on-farm work, contact with pets in general, and particularly carnivores, and contact with animal traders. The symptoms associated with the disease were myalgia and fever, and the treatment of the symptoms provided some protection. 相似文献
184.
During a five-year survey including studies on the parasite fauna of bream (Abramis brama), four gill-parasitic Myxobolus species (M. bramae, M. hungaricus, M. impressus and M. macrocapsularis) were recorded in a total of 313 breams from Lake Balaton. The commonest species, M. bramae showed a prevalence of 33%, while the other species occurred sporadically. Myxobolus bramae and M. macrocapsularis infected the tips of the gill filaments and caused both intralamellar and interlamellar infection. Intralamellar plasmodia of small size developed in the capillary network of the gill lamellae whereas the much larger interlamellar plasmodia were formed in the arteria afferens. The intralamellar plasmodia of M. hungaricus always infected the basal or central part of the gill filaments. In contrast to the above species developing in the blood vessels, M. impressus proved to be an epithelial parasite, as its plasmodia always developed in the adjacent gill filaments of two opposite haemibranchia, in the stratified epithelium between the respiratory plates, causing changes of the haemibranchium which were well visible even by the naked eye. 相似文献
185.
Orchiectomy was performed in a 37-year-old Hungarian man exhibiting a swelling in his right testicle. Histology revealed a nodule attached to the spermatic cord, consisting of a granulomatous tissue around sections of a nematode. The worm was identified as Dirofilaria repens, an uncommon parasite in Hungary. As the patient had been abroad only in Italy where cases of dirofilariosis in dogs and humans are relatively frequent, it is assumed that the infection might have been acquired in that country 5 years earlier. This is the fifth case, published so far in the world, of such a localization in a human. The human cases of dirofilariosis reported in Hungary are reviewed. 相似文献
186.
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188.
Ch Damdinsurén 《Archiv fuer experimentelle veterinaermedizin》1989,43(5):769-772
The authors of this paper have produced live vaccine to cope with infectious agalactia in goat. The vaccine (culture) was used on 360, 924 goats kept on ajmaks in Bajanchongor and Gobi-Altaj, in 1986. The number of pathologically affected goats went down by a factor of 4.5, as compared to 1985. Mortality was reduced to one third. Abortions declined by a factor of 2.6 and infertility among goats by 1.6. The conclusion is that sheep of the Mongolian breed are not susceptible to infectious agalactia. Large-scale production tests of live cultures supported hopes for successful action on this infectious disease under Mongolian conditions. 相似文献
189.
190.