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991.
Richardson DJ 《Science (New York, N.Y.)》2010,330(6002):327-328
992.
Optical clocks and relativity 总被引:1,自引:0,他引:1
Observers in relative motion or at different gravitational potentials measure disparate clock rates. These predictions of relativity have previously been observed with atomic clocks at high velocities and with large changes in elevation. We observed time dilation from relative speeds of less than 10 meters per second by comparing two optical atomic clocks connected by a 75-meter length of optical fiber. We can now also detect time dilation due to a change in height near Earth's surface of less than 1 meter. This technique may be extended to the field of geodesy, with applications in geophysics and hydrology as well as in space-based tests of fundamental physics. 相似文献
993.
Periodicity in host availability is common in agricultural systems. Although it is known to have profound effects on plant pathogen abundance, the evolutionary consequences of periodicity for the pathogen population have not previously been analyzed. An epidemiological model incorporating periodic absence of the host crop is combined with the theory of adaptive dynamics to determine whether or not seasonality in host presence plays a role in the occurrence of evolutionary branching, leading to coexisting yet genetically distinct pathogen phenotypes. The study is motivated and illustrated by the specific example of take-all disease of wheat, caused by the pathogen Gaeumannomyces graminis var. tritici, for which two coexisting but genetically distinct types and a trade-off related to seasonality in host presence have been identified. Numerical simulations are used to show that a trade-off between the pathogen transmission rate and the survival of the pathogen between cropping seasons cannot account for the evolutionary branching observed in many pathogens. Model elaborations show that this conclusion holds for a broad range of putative mechanisms. Although the analysis is motivated and illustrated by the specific example of take-all of wheat, the results apply to a broad range of pathogens. 相似文献
994.
995.
Gardner JM Devoss JJ Friedman RS Wong DJ Tan YX Zhou X Johannes KP Su MA Chang HY Krummel MF Anderson MS 《Science (New York, N.Y.)》2008,321(5890):843-847
The prevention of autoimmunity requires the elimination of self-reactive T cells during their development and maturation. The expression of diverse self-antigens by stromal cells in the thymus is essential to this process and depends, in part, on the activity of the autoimmune regulator (Aire) gene. Here we report the identification of extrathymic Aire-expressing cells (eTACs) resident within the secondary lymphoid organs. These stromally derived eTACs express a diverse array of distinct self-antigens and are capable of interacting with and deleting na?ve autoreactive T cells. Using two-photon microscopy, we observed stable antigen-specific interactions between eTACs and autoreactive T cells. We propose that such a secondary network of self-antigen-expressing stromal cells may help reinforce immune tolerance by preventing the maturation of autoreactive T cells that escape thymic negative selection. 相似文献
996.
The pathogenesis of five different Newcastle disease virus (NDV) isolates representing all pathotypes was examined in commercial and specific pathogen-free (SPF) turkeys. Experimentally-infected birds were monitored clinically and euthanatized, with subsequent tissue collection, for examination by histopathology, by immunohistochemistry for the presence of NDV nucleoprotein, and by in situ hybridization for the presence of replicating virus. Clinically, the lentogenic pathotype did not cause overt clinical signs in either commercial or SPF turkeys. Mesogenic viruses caused depression in some birds. Turkeys infected with velogenic neurotropic and velogenic viscerotropic isolates showed severe depression, and neurologic signs. Histologic appearances for all strains had many similarities to lesions observed in chickens inoculated with the various isolates; that is, lesions were present predominantly in lymphoid, intestinal, and central nervous tissues. However, in general, disease among turkeys was less severe than in chickens, and turkeys could be considered a subclinical carrier for some of the isolates. 相似文献
997.
998.
Duyvis MG Hilhorst R Laane C Evans DJ Schmedding DJ 《Journal of agricultural and food chemistry》2002,50(6):1548-1552
A method for the quantitative determination of riboflavin levels in beer was developed. The method is based on the quenching of riboflavin fluorescence, which occurs when riboflavin binds to the aporiboflavin-binding protein from egg white. The method does not require any pretreatment of the beer before analysis, other than dilution, and proved to be simple, reliable, and sensitive. The lowest concentration that could be detected was approximately 10 nM riboflavin. The possible interference of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) with the determination of the riboflavin content of beer was excluded, because beer contains only a very small amount of FAD (0.03 microM) and no FMN. The riboflavin levels of the types and brands of beer investigated were in the range of 0.5-1.0 microM. The origin of the riboflavin in beer proved to be the malt. Hop and yeast hardly contributed to the riboflavin content of beer. Besides its use in the determination of riboflavin levels, the aporiboflavin-binding protein also provides a way to remove riboflavin from beer, which reduces the light sensitivity and the related lightstruck off-flavor formation in beer. 相似文献
999.
Effects of landscape corridors on seed dispersal by birds 总被引:1,自引:0,他引:1
Levey DJ Bolker BM Tewksbury JJ Sargent S Haddad NM 《Science (New York, N.Y.)》2005,309(5731):146-148
Habitat fragmentation threatens biodiversity by disrupting dispersal. The mechanisms and consequences of this disruption are controversial, primarily because most organisms are difficult to track. We examined the effect of habitat corridors on long-distance dispersal of seeds by birds, and tested whether small-scale (<20 meters) movements of birds could be scaled up to predict dispersal of seeds across hundreds of meters in eight experimentally fragmented landscapes. A simulation model accurately predicted the observed pattern of seed rain and revealed that corridors functioned through edge-following behavior of birds. Our study shows how models based on easily observed behaviors can be scaled up to predict landscape-level processes. 相似文献
1000.
Glew RS Vanderjagt DJ Chuang LT Huang YS Millson M Glew RH 《Plant foods for human nutrition (Dordrecht, Netherlands)》2005,60(4):187-193
Non-cereal plant foods in the Western Sahel of Africa contribute significantly to the diets of local residents, especially
during periods of grain shortages. In this paper, we analyze four such plant foods including diyan kwakwa (nut of coconut palm, Cocos nucifera L.), muricin giginya (young shoot of Borassus aethiopum), tsamiya biri (fruit of the tree, Tamarindus indica), and yari (a mixture of lichens, mainly Rimelia reticulate) that grows on ebony trees (Diospyros mespiliformis). They were analyzed for their content of amino acids, fatty acids, and minerals. Although diyan kwakwa contained the highest protein content (27.1%), its protein quality fell below the WHO standard in 3 of 8 essential amino
acid categories. Yari and muricin giginya contained moderate levels of good quality protein. Only diyan kwakwa contained calorically significant amount of total fatty acid (24.7%); however, none of the plants contained useful amounts
of the essential fatty acids, linoleic acid, or α-linolenic acid. All four plants contained useful amounts of zinc (> 12 μg/g
dry weight), while yari contained the most calcium (14.7 mg/g dry weight) and iron (1.41 mg/g), and diyan kwakwa the most copper. All the four plant foods contained lesser amounts of magnesium, molybdenum, or selenium. These data indicate
that the four plants contain useful amounts of various essential nutrients that could supplement the diets of populations
inhabiting the Western Sahel. 相似文献