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排序方式: 共有116条查询结果,搜索用时 0 毫秒
111.
Anish Kundu Adinpunya Mitra 《Plant foods for human nutrition (Dordrecht, Netherlands)》2013,68(3):247-253
Acetylcholinesterase inhibitors (AChEIs) are important for treatment of Alzheimer’s disease and other neurological disorders. Search for potent and safe AChEIs from plant sources still continues. In the present work, we explored fragrant plant extracts that are traditionally used in flavoring foods, namely, Hemidesmus indicus and Vanilla planifolia, as possible sources for AChEI. Root and pod extracts of H. indicus and V. planifolia, respectively, produce fragrant phenolic compounds, 2-hydroxy-4-methoxybenzaldehyde (MBALD) and 4-hydroxy-3-methoxybenzaldehyde (vanillin). These methoxybenzaldehydes were shown to have inhibitory potential against acetylcholinesterase (AChE). Vanillin (IC50?=?0.037 mM) was detected as more efficient inhibitor than MBALD (IC50?=?0.047 mM). This finding was supported by kinetic analysis. Thus, plant-based food flavoring agents showed capacity in curing Alzheimer’s disease and other neurological dysfunctions. 相似文献
112.
High-resolution microwave observations are providing new insights into the nature of active regions and eruptions on the sun and nearby stars. The strength, evolution, and structure of magnetic fields in coronal loops can be determined by multiple-wavelength observations with the Very Large Array. Flare models can be tested with Very Large Array snapshot maps, which have angular resolutions of better than 1 second of arc in time periods as short as 10 seconds. Magnetic changes that precede solar eruptions on time scales of tens of minutes involve primarily emerging coronal loops and the interactions of two or more loops. Magnetic reconnection at the interface of two closed loops may accelerate electrons and trigger the release of microwave energy in the coronal parts of the magnetic loops. Nearby main-sequence stars of late spectral type emit slowly varying microwave radiation and stellar microwave bursts that show striking similarities to those of the sun. 相似文献
113.
This study was exclusively conducted to evaluate healing of surgically created defects on the radius of adult Black Bengal goat after implantation of porous bioglass blocks and compare the process kinetics with normal healing. Twelve Black Bengal goats were divided randomly into two groups: control and experimental group implanted with bioglass blocks. Unicortical bone defects in radius were generated in all animals under aseptic condition. Local inflammatory reaction and healing of wound, radiological investigations, histological studies, oxytetracycline leveling and angiographic studies were performed up to 90th day post-operatively and compared with normal healing. It has been found that extensive new bone formation originating from host bone towards the implant whereas in control, the process was active from both the ends; the defect site appeared as homogenous nonfluorescent area. Thus, porous bioglass promoted bone formation over the entire extension of the defect independent of size of block in comparison to control group. 相似文献
114.
Roberta Teta Germana Esposito Karishma Kundu Mariano Stornaiuolo Silvia Scarpato Antonino Pollio Valeria Costantino 《Marine drugs》2022,20(4)
In this study, a strain of Anabaena flos-aquae UTEX 1444 was cultivated in six different concentrations of iron (III). Cultures were extracted with organic solvents and analyzed using our dereplication strategy, based on the combined use of high-resolution tandem mass spectrometry and molecular networking. The analysis showed the presence of the siderophores’ family, named synechobactins, only in the zero iron (III) treatment culture. Seven unknown synechobactin variants were present in the extract, and their structures have been determined by a careful HRMS/MS analysis. This study unveils the capability of Anabaena flos-aquae UTEX 1444 to produce a large array of siderophores and may be a suitable model organism for a sustainable scale-up exploitation of such bioactive molecules, for the bioremediation of contaminated ecosystems, as well as in drug discovery. 相似文献
115.
Differential behaviour of sheath blight pathogen Rhizoctonia solani in tolerant and susceptible rice varieties before and during infection
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This study characterized the early infection and establishment of the sheath blight pathogen Rhizoctonia solani on a tolerant rice variety, Swarnadhaan (IET 5656), and a susceptible variety, Swarna (MTU 7029). Assays using whole plants showed that disease severity was higher in Swarna than Swarnadhaan. In a detached leaf assay, Swarnadhaan showed a disease index that was 50% less than that with Swarna. Rhizoctonia solani exhibited different growth behaviour in the tolerant and susceptible varieties. The pathogen showed more hyphal growth in the susceptible host than in the tolerant variety. It also showed profuse branching, making intimate contact with the host surface to form more inter‐ and intracellular structures, and greater sclerotial development in the susceptible host compared to the tolerant one. Using light and scanning electron microscopy, it was observed for the first time that the pathogen could intercept host surface structures and use these for anchorage or penetration. Transformed R. solani, expressing green fluorescent protein, was observed using confocal laser scanning microscopy to investigate pathogen behaviour, including the formation of infection cushions and subsequent colonization of the host tissues. This is the first ultrastructural report to characterize the differential behaviour of the sheath blight pathogen in the vicinity and within tolerant and susceptible rice plants. 相似文献
116.
S. Kundu Ranjan Bhattacharyya Ved Prakash H. S. Gupta H. Pathak J. K. Ladha 《Biology and Fertility of Soils》2007,43(3):271-280
A long-term (30 years) soybean–wheat experiment was conducted at Hawalbagh, Almora, India to study the effects of organic
and inorganic sources of nutrients on grain yield trends of rainfed soybean (Glycine
max)–wheat (Triticum
aestivum) system and nutrient status (soil C, N, P and K) in a sandy loam soil (Typic Haplaquept). The unfertilized plot supported
0.56 Mg ha−1 of soybean yield and 0.71 Mg ha−1 of wheat yield (average yield of 30 years). Soybean responded to inorganic NPK application and the yield increased significantly
to 0.87 Mg ha−1 with NPK. Maximum yields of soybean (2.84 Mg ha−1) and residual wheat (1.88 Mg ha−1) were obtained in the plots under NPK + farmyard manure (FYM) treatment, which were significantly higher than yields observed
under other treatments. Soybean yields in the plots under the unfertilized and the inorganic fertilizer treatments decreased
with time, whereas yields increased significantly in the plots under N + FYM and NPK + FYM treatments. At the end of 30 years,
total soil organic C (SOC) and total N concentrations increased in all the treatments. Soils under NPK + FYM-treated plots
contained higher SOC and total N by 89 and 58% in the 0–45 cm soil layer, respectively, over that of the initial status. Hence,
the decline in yields might be due to decline in available P and K status of soil. Combined use of NPK and FYM increased SOC,
oxidizable SOC, total N, total P, Olsen P, and ammonium acetate exchangeable K by 37.8, 42.0, 20.8, 30.2, 25.0, and 52.7%,
respectively, at 0–45 cm soil layer compared to application of NPK through inorganic fertilizers. However, the soil profiles
under all the treatments had a net loss of nonexchangeable K, ranging from 172 kg ha−1 under treatment NK to a maximum of 960 kg ha−1 under NPK + FYM after 30 years of cropping. Depletion of available P and K might have contributed to the soybean yield decline
in treatments where manure was not applied. The study also showed that although the combined NPK and FYM application sustained
long-term productivity of the soybean–wheat system, increased K input is required to maintain soil nonexchangeable K level. 相似文献