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排序方式: 共有93条查询结果,搜索用时 187 毫秒
1.
R C Cutlip H D Lehmkuhl J M Sacks A L Weaver 《Journal of the American Veterinary Medical Association》1992,200(6):802-805
Goats from 28 states were tested for antibodies to caprine arthritis-encephalitis virus. Of 3,790 goats, 1,175 (31%) tested positive, and of 196 herds tested, 143 (73%) had 1 or more seropositive members. This prevalence, based on serum samples from all goats in the participating herds, was lower than most rates reported in other studies. Such studies were based on fewer samples, incomplete sampling of herds, or smaller geographic base. Prevalence was highest in western Pacific and northern plains regions, increased with age to 3 years, was highest among goats on family-owned farms, and was lowest in the Angora breed. Differences in prevalence was not related to gender or size of herd. 相似文献
2.
A bovine adenovirus with agglutinating activity was isolated from feedlot calves and classified as serotype 3. The agglutinating activity was shown to be the property of an adenovirus-associated virus (AAV). The AAV was isolated from the bovine adenovirus by isopycnic centrifugation in CsCl; the AAV had a density of 1.4 g/cm2. This AAV is serologically related to bovine AAV-TR-15, but is distinct from bovine parvovirus-1 and primate AAV types 1 to 4, using counterimmunoelectrophoresis and hemagglutination-inhibition. 相似文献
3.
Oglesbee BL Lehmkuhl L 《Journal of the American Veterinary Medical Association》2001,218(3):376-80, 360
Congestive heart failure was diagnosed in a 27-year-old Indian ringneck parakeet with exercise-induced dyspnea. A grade IV/VI holosystolic murmur that radiated to the right sternal area was auscultated over the left side of the sternum. Radiography revealed progressive cardiomegaly, hepatomegaly, pulmonary edema, and accumulation of fluid within the coelomic cavity. Echocardiography revealed biatrial enlargement and enlargement of the right ventricle. Doppler recording revealed high velocity left and right atrioventricular valve regurgitation. Treatment with digoxin and furosemide alleviated clinical signs for approximately 10 months. Gross postmortem examination revealed cardiac enlargement and eccentric hypertrophy of both ventricles on cross-section. Pulmonary congestion and edema, hepatomegaly, hepatic congestion, and ascites were also evident. Histologic examination of the heart revealed myxomatous degeneration of the left atrioventricular valve, muscular hypertrophy of the right atrioventricular valve, and biventricular chronic myofiber degeneration and necrosis. 相似文献
4.
Oyama MA Sisson DD Lehmkuhl LB 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2001,15(3):229-239
Artificial pacing (AP) is a treatment for symptomatic bradyarrhythmias unresponsive to medical therapy. This retrospective study was designed to define the practices and outcome of AP in dogs at 7 referral institutions participating in the Companion Animal Pacemaker Registry and Repository (CANPACERS). The indications, implantation techniques, complications, long-term outcome, and owner satisfaction were examined. One hundred fifty-four dogs were identified as undergoing AP from January 1, 1991, to January 1, 1996. Third-degree atrioventricular (AV) block (n = 91; 59%) and sinus node dysfunction (n = 45; 29%) were the most common indications for AP Transvenous endocardial AP systems were implanted in 136 dogs (88%), and epicardial systems were implanted in 18 (12%). Complications associated with AP were reported in 84 dogs (55%). Major complications occurred in 51 dogs (33%), including dislodgement of the pacing lead (n = 15; 10%), generator failure (n = 10; 6%), cardiac arrest during implantation (n = 9; 6%), and infection (n = 7; 5%). Minor complications occurred in 47 dogs (31%), including seroma formation (n = 18; 12%), muscle twitch (n = 17; 11%), and inconsequential arrhythmias (n = 15; 10%). Fourteen dogs (9%) experienced both major and minor complications. Survival analysis revealed 1-, 2-, and 3-year survival rates of 70, 57, and 45%, respectively. Age and presence of preexisting congestive heart failure (CHF) had a negative effect on survival (P = .001). Sixty percent of dogs with preexisting CHF died within 1 year of implantation, whereas 25% of dogs without heart failure died during the same period. Owners rated their satisfaction with the procedure as high in 80% of the dogs. 相似文献
5.
Woods LW Hanley RS Chiu PH Lehmkuhl HD Nordhausen RW Stillian MH Swift PK 《Veterinary pathology》1999,36(2):100-110
Adenovirus infection was the cause of an epizootic of hemorrhagic disease that is believed to have killed thousands of mule deer (Odocoileus hemionus) in California during the latter half of 1993. A systemic vasculitis with pulmonary edema and hemorrhagic enteropathy or a localized vasculitis associated with necrotizing stomatitis/pharyngitis/glossitis or osteomyelitis of the jaw were common necropsy findings in animals that died during this epizootic. To study transmission of adenovirus infection in deer and susceptibility of black-tailed deer (Odocoileus hemionus columbianus) fawns to adenovirus infection, six 3-6-month-old black-tailed fawns were divided into two treatment groups. One group was inoculated intravenously and the other group was inoculated through the mucous membranes of the eyes, nose and mouth with purified adenovirus. Each treatment group also included two additional fawns (four total) that were not inoculated but were exposed to inoculated animals (contact animals). One fawn served as a negative control. Between 4 and 16 days postinoculation, 8/10 fawns developed systemic or localized infection with lesions identical to lesions seen in animals with natural disease that died during the epizootic. Transmission was by direct contact, and the route of inoculation did not affect the incubation period or the distribution of the virus (systemic or the localized infection). Immunohistochemical analysis using polyclonal antiserum against bovine adenovirus type 5 demonstrated staining in endothelial cells of vessels in numerous tissues in animals with systemic infection and endothelial staining only in vessels subtending necrotic foci in the upper alimentary tract in animals with the localized form of the disease. All inoculated or exposed animals had staining in the tonsillar epithelium. Transmission electron microscopic examination of lung and ileum from two fawns with pulmonary edema and hemorrhagic enteropathy demonstrated endothelial necrosis and adenovirus virions in endothelial cell nuclei. Adenovirus was reisolated in black-tailed deer pulmonary artery endothelial cells using lung homogenate of the first fawn that developed systemic adenovirus infection. Serum virus neutralization test results suggest that this deer adenovirus is a new serotype. 相似文献
6.
Matthew W. Miller DVM Dipl ACVIM Sonya G. Gordon DVM Dipl ACVIM Ashley B. Saunders DVM Dipl ACVIM Wendy G. Arsenault DVM Dipl ACVIM Kathryn M. Meurs DVM Dipl ACVIM Linda B. Lehmkuhl DVM Dipl ACVIM John D. Bonagura DVM Dipl ACVIM Philip R. Fox DVM Dipl ACVIM Dipl ECVIM 《Journal of Veterinary Cardiology》2006,8(2):109-114
7.
8.
Young lambs, inoculated with ovine adenovirus isolate RTS-151, were killed sequentially (to postinoculation day 21), and their morphologic lesions were studied. Lesions were found only in the respiratory tract and were most severe in the terminal airways. Many cells of the respiratory epithelium had severe cytomegaly and karyomegaly with intranuclear inclusions. Desquamation of affected cells was accompanied by hyperplasia of airway and alveolar epithelium and by accumulation of necrotic cellular debris and neutrophils in terminal airways and alveoli. Virus replicated in the nucleus of enlarged epithelial cells in the airways, but not in alveolar epithelium. Intranuclear inclusions representing viral replication progressed from clumps of finely granular material without virions to a granular material with virions and finally to a dense inclusion with numerous virions. 相似文献
9.
10.
B R LeaMaster J F Evermann H D Lehmkuhl 《Journal of the American Veterinary Medical Association》1987,190(12):1545-1547
Eight hundred fourteen Polypay-cross lambs, 32 to 35 days old, were housed in an isolation barn under semiconfinement conditions. The lambs were observed twice daily for clinical signs of respiratory tract disease. During the 8-week observation period, an epizootic of respiratory tract disease developed, in which the combined morbidity and mortality was approximately 13%. The overall mortality was 4.1%, of which 57.6% was attributable to pneumonia. Pasteurella haemolytica was isolated from 11 (58%) of the 19 lung specimens obtained at necropsy. Serotyping revealed the presence of multiple serotypes: A1, A2, A5, A6, A9, and A12. Viruses with properties consistent with ovine adenovirus were isolated from 36% of the lung specimens. Five of the isolates were selected to determine their antigenic serotype. Results of virus neutralization testing indicated that in this group of lambs, there was concurrent infection with Mastadenovirus ovi type 5 and type 6. 相似文献