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J. H. Heckman H. G. Zuckerman C. H. Metzger B. A. Brown E. R. Bennett W. B. Ward C. L. Fitch O. H. Elmer Jhon S. Gardner Julan C. Miller Frank W. Hussey E. L. Newdick Ralph W. Donaldson Lionel Harris H. O. Werner Wm. H. Martin E. V. Hardenburg T. E. Odland Robert Schmidt Geo E. Prince Brooks D. Drain Harold L. Bailey G. S. Ralston Chase D. Gaines J. G. Milward John Tucker 《American Journal of Potato Research》1935,12(6):158-170
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E. Marx C. H. Metzger B. A. Brown Eugene W. Whitman H. R. Talmage Frank W. Hussey H. A. Reiley Marx Koehnke J. C. Campbell E. V. Hardenburg Karl H. Fernow Earl B. Tussing E. R. Jackman C. A. Henderson O. D. Burke K. W. Lauer John Noonan H. L. Bailey Chas D. Gaines W. N. Keenan R. E. Goodin 《American Journal of Potato Research》1943,20(8):224-236
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A trial using 64 weanling pigs (TR4×PIC C22) was conducted to determine the effects of menhaden fish oil supplementation and diet complexity on performance and immune response of nursery pigs. Pigs (17 days and 6.27±1.16 kg) were weaned into a segregated early wean facility and given free access to a complex diet for 7 days post-weaning. At day 0 (day 7 post-weaning), pigs were blocked by weight and allotted to 64 pens. Treatments (Trt) were arranged as a 2×2×2 factorial arrangement. Main effects included diet (complex versus simple), oil (menhaden fish (MFO) versus corn (CO)), and immunogen (saline versus lipopolysaccharide (LPS)). Experimental diets contained 6% oil (6% CO or 5% MFO+1% CO) and were fed for 14 days. On day 12, i.v. injections of either LPS (150 μg/kg) or saline were given, followed by blood collection at 30 min intervals for 6 h. After the immune challenge (day 14), pigs were placed onto a common corn-soybean meal fortified diet and growth performance was evaluated until termination of the study (day 28). Pigs were weighed and feed intakes recorded at 7, 14, and 28 days. Prior to immune challenge (day 12), there were differences in BW for pigs fed complex versus simple diets (P<0.01; 13.1 and 12.1 kg, respectively) and pigs fed CO versus MFO diets (P<0.05; 12.9 and 12.3 kg, respectively). During the challenge period, for pigs treated with LPS there was a Time×Immunogen×Oil effect (P<0.001) for serum cortisol with MFO fed pigs having lower serum cortisol as compared to CO fed pigs. Also, during the challenge period, for pigs treated with LPS there was a Time×Diet×Immunogen×Oil effect (P<0.001) for serum tumor necrosis factor- (TNF-) with pigs fed complex diets supplemented with CO having higher serum TNF- as compared with pigs fed complex diets supplemented with MFO. At days 14 and 28, LPS-treated pigs had lower BW than saline injected controls (P<0.001 and 0.01, respectively). In addition, pigs fed simplified diets continued to have lower BW after challenge compared to pigs fed a complex diet. Interestingly, there were no differences (P>0.10) in BW after challenge in pigs fed MFO. This study suggests that MFO supplementation alters the immune response during LPS challenge and that simplified diets may compromise nursery performance. 相似文献
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