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鸡球虫病是严重危害养鸡业发展的疾病之一,其中以柔嫩艾美耳球虫引起的球虫病最普遍.集约化养鸡场是球虫病爆发的最适宜场所,其发病率为50%~70%,严重时高达80%,带来了严重的经济损失.该病主要依靠化学药物进行防治,但球虫耐药性问题给临床防治带来很大麻烦[1].中药具有毒副作用小、药物残留低、不易产生耐药性等优点,并能增强机体抵抗力、促进机体生长等.试验依据中兽医理论和鸡球虫病特点,在总结国内外有关中药防治球虫病研究资料的基础上,对比研究了常山、青蒿及二者的提取物对防治雏鸡球虫病的效果,以便为临床提供有效的绿色抗球虫药物. 相似文献
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<正>鸡球虫病是由艾美耳属球虫寄生于鸡肠道上皮细胞内引起的一种原虫病,该病分布广泛,鸡群一旦感染会造成生长迟缓、产蛋量下降,甚至大批死亡,给养鸡业造成的危害严重。目前,临床上用于防治鸡球虫病的药物主要是离子载体抗生素和化学合成药物,但是由于抗药虫株的不断出现及抗球虫化学药物的严重残留等一系列问题,使用毒副作用小、无残留的中草药防治该病便显得十分重要。因此,常青克球灵防治鸡球虫病的应用研究课题组根据中药药理学理论[1-2]及鸡球虫病的发病机制,研制出抗球虫效果好 相似文献
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正鸡球虫病是我国养鸡生产中常见且危害大的疾病。近年来,由于球虫耐药性问题以及严峻的食品安全形势,采用疫苗代替抗球虫药来预防鸡球虫病的人越来越多。然而,目前的鸡球虫病疫苗均为活卵囊疫苗,免疫接种后需在鸡体发育繁殖,刺激机体免疫应答。所以,在小鸡阶段鸡体建立抗球虫免疫力期间,要避免使用抗球虫药和广谱抗菌抗球虫类药物,比如磺胺类、四环素类药物。为了解一些中药对鸡球虫病活疫苗卵囊繁殖的影响,特此进行本试验,以便为接种球虫病疫苗的鸡群选用药物提供依据。1材料与方法1.1供试药物 相似文献
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鸡球虫病属常见的寄生虫疾病,危害范围较广因一种或多种球虫诱发.日常诊断鸡球虫病,可自如下三方面着手:生产性能、典型症状、实验室检查.在此基础上,提出了强化消毒清灭虫卵、继续推广球虫免疫、及时辅助治疗、尝试用抗球虫中药剂、控制球虫用化学药物防治等综合防治措施,以供参考和借鉴. 相似文献
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鸡的球虫病是鸡的一种常见疾病。该病对鸡的危害很大,轻者造成鸡的采食量减少,增重下降,产蛋量降低,重者可造成停产或导致死亡。因此,使用抗球虫药物是防治鸡球虫病的有效措施。但是只有在正确使用好抗球虫药物时,才能达到控制球虫病的发生。(一)应当按致病虫种选择使用抗球虫药抗球虫药物对不同种球虫的作用效果存有一定的差异。各种球虫的致病力和致病部位不同,因此,对药物的敏感性也不尽相同。虽然在临床上球虫病多为多种球虫病混合感染,但不同场所的主要致病虫种差别却很大,这是抗球虫药物防治效果存在差异的主要原因之一,不同球虫对药… 相似文献
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孟伟 《河南畜牧兽医(综合版)》2008,29(21)
自1929年Levine发现磺胺类药物具有抗球虫作用以来,已证实具有不同程度抗球虫作用的药物达百余种,临床用于防治鸩球虫病的药物也有30多种.但是,药物防治鸡球虫病的历史证明,球虫对之产生抗药性是不可避免的.因此,要有效地防治鸡球虫病,必须不断地研制开发新的抗球虫药物.为了检验人工合成青蒿素对鸡柔嫩艾美耳球虫病(盲肠球虫病)的预防效果,特进行了此项试验. 相似文献
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四株柔嫩艾美尔球虫对四种抗球虫药的抗药性研究 总被引:2,自引:0,他引:2
自从Levine(1939)发现磺胺类药物具有抗球虫作用以来,至今用于防治鸡球虫病的药物已达40多种。抗球虫药物的使用,对于减轻鸡球虫病的危害,确保养鸡业的发展起到了极大作用。但前人的研究证明,球虫几乎对所有使用过的抗球虫药物都有抗药虫株出现。球虫抗药性的产生,导致抗球虫药物使用年限缩短,防治失败或效果不佳,引起临床或亚临床球虫病,造成很大的经济损失。因此,抗药性是鸡球虫病防治对策中最严重的一个问题。 相似文献
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《饲料工业》2019,(18):54-58
应用电感耦合等离子-质谱技术(ICP-MS),建立饲料中钠、镁、铬、锰、铁、铜、锌、砷、硒、镉和铅等元素的测定方法。对饲料样品的前处理方法、仪器工作参数和11种元素标准曲线进行优化;并以加标回收、分析方法比对和重复测试说明方法的准确性和精密性。方法在0~1 000 ng/ml范围内线性良好,仪器检出限为0.557 7~5.072 ng/ml,具有良好的精密度,其回收率在88.1%~104.4%之间,相对标准偏差小于5.0%。同时与原子吸收和原子荧光方法进行比对,测定结果相近。所建立的方法简单、快速,可替代原子吸收和原子荧光方法测定饲料中的11种金属元素,为饲料的质量控制提供理想的元素分析方法。 相似文献
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In experiment 1, 6 pregnant mares received a concentrate that contained a trace mineral premix that provided 14.3 mg Cu, 40 mg Zn, 28 mg Fe, 28 mg Mn, 0.08 mg Co, 0.16 mg I, and 0.16 mg Se/kg concentrate (group A). Seven mares received the same concentrate plus 502 mg Zn and 127 mg Cu once daily (group B). No differences (P > .05) in foal growth data, or Cu, Zn, and Fe concentrations of mare milk, mare serum, or foal serum were observed. In experiment 2, 6 pregnant mares received the same concentrate as group A (group C), and 8 mares received the same concentrate fortified with 4× the trace mineral premix (group D). Group C mares had higher serum Zn concentration at 1 day (P < 0.01) and 56 days (P < 0.04). Group C mares had higher milk Fe concentration at 28 days (P < .01), and group D mares had higher milk Cu concentration at 56 days (P < .01). Group C foals had higher serum Cu concentration at 14 days (P < .03). The results from this study provide no evidence to indicate that supplementing late gestating and lactating mares with higher dietary trace mineral levels than those recommended currently by NRC has any influence on foal growth and development, or on the Cu, Zn, and Fe concentrations of the mare milk, mare serum, or foal serum. 相似文献
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Breed differences for weight (CW), height (CH), and condition score (CS) were estimated from records (n = 12,188) of 2- to 6-yr-old cows (n = 744) from Cycle IV of the U.S. Meat Animal Research Center's Germplasm Evaluation (GPE) Program. Cows were produced from mating Angus and Hereford dams to Angus, Hereford, Charolais, Shorthorn, Galloway, Longhorn, Nellore, Piedmontese, and Salers sires. Samples of Angus and Hereford sires were 1) reference sires born from 1962 through 1970 and 2) 1980s sires born in 1980 through 1987. The mixed model included cow age, season of measurement and their interactions, year of birth, pregnancy-lactation code (PL), and breedgroup as fixed effects for CW and CS. Analyses of weight adjusted for condition score included CS as a linear covariate. The model for CH excluded PL. Random effects were additive genetic and permanent environmental effects associated with the cow. Differences among breed groups were significant (P < 0.05) for all traits and were maintained through maturity with few interchanges in ranking. The order of F1 cows for weight was as follows: Charolais (506 to 635 kg for different ages), Shorthorn and Salers, reciprocal Hereford-Angus (HA) with 1980s sires, Nellore, HA with reference sires, Galloway, Piedmontese, and Longhorn (412 to 525 kg for different ages). Order for height was as follows: Nellore (136 to 140 cm), Charolais, Shorthorn, Salers, HA with 1980s sires, Piedmontese, Longhorn, Galloway and HA with reference sires (126 to 128 cm). Hereford and Angus cows with reference sires were generally lighter than those with 1980s sires. In general, breed differences for height followed those for weight except that F1 Nellore cows were tallest, which may in part be due to Bos taurus-Bos indicus heterosis for size. 相似文献
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采用液相色谱-串联质谱法测定动物尿液中11种β-受体激动剂残留量,对标准溶液、体积、质谱峰面积、浓缩过程及回收率等测定不确定度因素进行了分析,通过评定各不确定度分量及标准不确定度,得出11种β-受体激动剂的扩展不确定度在0.7 ~ 1.1 ng/mL范围内.由各因素对合成不确定度的贡献比分析可知,影响较大的因素为试验回收率及标准溶液浓度. 相似文献
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K Reifenberg M Stahl U L?sch 《Zentralblatt für Veterin?rmedizin. Reihe B. Journal of veterinary medicine. Series B》1989,36(3):191-198
A simple two step procedure for the isolation of caprine, ovine, bovine, equine, canine, porcine and human peripheral blood granulocytes is described. After enrichment of granulocytes by centrifugation, contaminating erythrocytes are lysed hypotonically. Recovery, purity, and viability of the granulocyte suspensions are determined. FACScan analysis of the cell suspensions measuring cellular size by forward and sideward light scatter is compared with the corresponding analysis of whole blood leukocytes. Constituencies of the isolated cell suspensions and loss of granulocyte subpopulations through isolation procedure is discussed with regard to granulocyte function assays. 相似文献