研制中药"香参口服液"治疗仔猪腹泻病的效果试验

选择由白头翁、苦参、黄芩、广木香等8味中草药研制成“香参口服液”，对发生腹泻病的20日龄哺乳仔猪和35日龄断奶仔猪，每天100mL，分2次灌服，连用3－5d。其结果为“香参口服液”对治疗哺乳断奶仔猪腹泻疗效好，疗程短，治疗总有效率达86.35%，治愈率达77.25%。     

中药参五地不同复方制剂对仔猪腹泻的防治试验

为了观察复方中药制剂参五地口服液预防和治疗仔猪腹泻的临床效果,以及参五地散剂作为药物饲料添加剂预防断奶仔猪腹泻和促生长的作用,试验将腹泻仔猪随机分组,将参五地口服液与黄栀口服液、甲磺酸左氧氟沙星氯化钠注射液进行比较,观察参五地口服液的临床预防和治疗效果。参五地散按5 g/kg添加到断奶仔猪专用饲料中,观察用参五地散拌料预防断奶仔猪腹泻和促生长作用;药物对照组添加复方阿莫西林粉,按0.3 g/kg添加到饲料中;空白对照组不添加任何药物。结果表明:参五地口服液对未断奶仔猪的治愈率为88.57%,预防保护率为100%;参五地口服液对断奶仔猪的治愈率为90.00%,总有效率为95.00%;参五地散拌料对断奶仔猪腹泻的预防保护率为100%,第42天的平均日采食量极显著高于空白对照组(P0.01)。说明可以用参五地口服液预防和治疗未断奶仔猪腹泻,同时用参五地散拌料对断奶仔猪腹泻有良好的预防效果和明显的促生长作用。     

自配中西药方对仔猪腹泻病的对比治疗试验

本试验通过以塔里木盆地生长的中草药结合西药组成的菌痢停2号,与当地猪场对仔猪腹泻病治疗效果好的庆大霉素、氟哌酸进行对比治疗.结果表示:菌痢停2号与该猪场所选择的敏感药物庆大霉素、氟哌酸对仔猪腹泻病均有很好的疗效;菌痢停2号在治疗10～35日龄的患病仔猪时,与庆大霉素、氟哌酸相比,疗效显著,而在治疗10日龄以内的患病仔猪时,庆大霉素、氟哌酸的疗效明显好于菌痢停2号.     

中药"六一散"治疗仔猪黄白痢效果好

仔猪黄、白痢是由致病性大肠杆菌引起。其中仔猪黄痢常发生于出生1周以内,以1～3日龄居多,常全窝发病,发病率在90％以上,死亡率高达100％。仔猪白痢多发生于10～20日龄,发病率可达30%～80％,若不及时治疗,多成僵猪或死亡。笔者采用中药“六一散”治疗10例黄痢、20例白痢,治愈率达98％。现报道如下。     

"齐全一支灵"治疗畜禽痢疾效果好

“齐全一支灵”是四川遂宁市齐全饲料公司中西医结合研制的具有解热、消炎、镇痛、止痢平喘作用的膏剂。笔者经临床验证 ,该剂治疗畜禽痢疾 ,效果确实。1　病例介绍病例 1:民和县川口镇养猪规模户张某某的 2 0日龄仔猪 42头 ,35日龄仔猪 77头发生黄痢和白痢 ,经肌肉注射或口服各种抗生素 ,效果较差 ,死亡达 2 2头 ,改用本品治疗 ,每 2 0头仔猪喂 1支 ,2次 /ｄ ,结果死亡 2头 ,其余全部治愈。病例 2 :山城村张某某饲养的 36 0 0只 2 0日龄雏鸡 ,突然有 70 %左右雏鸡发生白痢和咳喘病 ,死亡率达 12 %。经此药治疗( 2 0 0～ 2 5 0只 /支 ) 3天…     

“益益久”与“杀痢王”治疗仔猪白痢的对比试验

历年来,我校牧场经常发生仔猪白痢。曾在饲料中添加痢特灵、氟哌酸,肌注链霉素、痢菌净等抗感染药物,但疗效不甚理想。我们在１９９８年９～１０月、１９９９年１～２月和４～５月,分别应用“益益久”复合微生物制剂和畜禽“杀痢王”口服液进行对比试验。目的是重复比较“益益久”复合微生物制剂和畜禽“杀痢王”口服液在不同季节对仔猪白痢的治疗效果和经济效益,为临床合理用药提供参考依据。现报告如下。１　材料和方法１－１　试验仔猪选择二元杂交母猪所产仔猪,年龄８～３５日龄,以排出白色浆糊样粪便的仔猪为治疗对象,同窝仔猪…     

猪流行性腹泻的诊疗体会

对两例疑似患有猪流行性腹泻病的病例猪进行综合施治,重症猪进行抗菌消炎、口服补液的对症治疗方案,同时采用＂特殊疗法＂辅以＂中药疗法＂进行强化救治,7日龄以上仔猪治疗效果显著。实践表明,对猪流行性腹泻病的治疗,必须采取综合防制措施,对症施治、重症特治则疗效更佳。     

中药“白连肝”口服液治疗鸭病毒性肝炎的试验报告

饲养无病毒性肝炎母源抗体雏鸭,于7日龄接种鸭肝炎病毒制作DVH模型,随机分为中药治疗组、西药治疗组、对照组。中药治疗组于7日龄、10日龄开始口服中药"白连肝"口服液,连用4 d。西药治疗组于7日龄、10日龄开始口服西药口服液,连用4 d。结果发现,与开始治疗时间相对应,口服中药组存活率达92%、84%;口服西药组存活率达72%、64%。     

仔猪黄痢的中西医结合防治措施

危害养猪健康发展的主要疾病之一是腹泻病,在腹泻病中,仔猪黄痢危害性较大,它是由某些病原性大肠杆菌引起初生仔猪的一种急性、高度致死性传染病,多发生于1周龄以内的仔猪,往往导致全窝发病、全窝死亡的现象出现。且猪场一旦发生此病,往往经生产母猪或污染环境感染初生仔猪而多年发病,很难根除,造成较大的经济损失。防治该病如单独使用抗生素,虽有一定疗效,但效果不佳。采取中西医结合治疗的措施,获得了较好的效果。1流行情况仔猪黄痢主要发生于初生1周以内的哺乳仔猪,以1~3日龄最多见,发病随日龄的增加而渐减,7日龄以上很少发病。传染源主…     

农村仔猪腹泻病发病情况调查及防控措施

为了加强农村仔猪腹泻病的防控,于2014年下半年和2015年上半年对广西天等县驮堪、进结两个乡(镇)的14个养殖场(户)临床症状表现为腹泻症的1~70日龄仔猪进行了发病情况调查。结果表明:所调查的14个养殖场(户)仔猪腹泻发病率为34.79%,死亡率为21.26%,病死率为61.11%;免疫仔猪腹泻发病率为16.55%,死亡率为3.52%;未免疫的仔猪发病率为38.08%,死亡率为23.68%;腹泻仔猪中64.00%是28日龄内的仔猪。引起仔猪腹泻的病原分别是大肠杆菌、沙门氏菌、魏氏梭菌、猪流行性腹泻病毒和猪传染性胃肠炎病毒,细菌检出率为70.45%,病毒检出率为23.86%。可见仔猪腹泻危害严重,主要危害对象是未断奶仔猪;适时免疫能减少腹泻病的发生及危害程度;细菌感染仍是引起仔猪腹泻病的最主要因素。     

商会自治的基石——商会自治规范研究

在现代法律秩序中,商会自治规范是制定法的基础和必要的补充,甚至在某些方面替代了制定法;商会自治规范主要包括商会组织规范、行为规范、惩罚规范以及争端解决规范等;其效力仅及于其内部成员;商会自治规范和制定法之间存在冲突,但也存在整合的基础。     

癸氧喹酯干混悬剂含量测定的改进

采用高效液相色谱法测定癸氧喹酯干混悬剂的含量,在2-250μg/mL范围内,峰面积的常用对数与进样量浓度的常用对数呈良好的线性关系,R^2=1(n=5),平均回收率为99.24%~99.51%,RSD在0.05%~0.28%。此方法分析时间短,样品前处理简便、定量结果准确,重现性好,结果满意,为其质量控制提供了依据。     

猪毛色遗传的研究进展

本文概述了猪的毛色类型、猪的毛色遗传模式,着重综述了猪毛色基因分子基础的研究进展,指出存在问题并就未来发展方向做了思考。     

Comparison of 2 methods of centesis of the bursa of the biceps brachii tendon of horses

REASONS FOR PERFORMING STUDY: Centesis of the bicipital bursa using an 8.9 cm long spinal needle has been reported but the alternative of employing a 3.8 cm long hypodermic needle requires validation. OBJECTIVE: To compare the efficacy of 2 different methods of centesis of the bicipital bursa and to evaluate the usefulness of ultrasonographic imaging to determine the location of solution administered when centesis of the bursa is attempted. METHODS: For Trial 1, 6 clinicians, who had no previous experience of centesis of the bicipital bursa, attempted to inject a solution composed of an aqueous radiopaque contrast medium and physiological saline solution (PSS) into the bicipital bursae of 2/12 horses using the previously described distal approach to inject one bursa and a proximal approach to inject the contralateral bursa. The bicipital tendon and bursa were examined ultrasonographically before and after injection; and both shoulders were examined radiographically to identify the location of the medium. In Trial 2, another 6 clinicians, also with no previous experience of centesis, repeated Trial 1, using 6 horses, but the radiopaque contrast medium was mixed with air instead of PSS. RESULTS: Accuracy of centesis using the proximal approach was 39% and that of the distal approach 28%. Ultrasonographic examination of the shoulder allowed the location of solution and air to be accurately predicted in all 12 shoulders examined. CONCLUSIONS: Clinicians who have had no previous experience performing centesis of the bicipital bursa are unlikely to be successful in centesis using either approach. Radiographic examination after injecting a radiopaque contrast medium may be necessary to assess the success of centesis especially if bursal fluid is not obtained during centesis. Injecting air along with the radiopaque contrast medium provides more accurate ultrasonographic confirmation of centesis and better radiographic definition than does injection without air.     

不同样本商品蜂蜜中硒含量的测定

用硝酸和高氯酸消化蜂蜜,使硒游离出来,在微酸性环境下,硒和2,3-二氨基萘(DAN)生成有较强荧光的物质,用环己烷萃取,在激发波长378nm,荧光波长518nm处测定其荧光强度。蜂蜜中硒含量范围:0.10～0.82μg/g。表明:蜂蜜应视为天然富硒营养品。     

乳酸杆菌益生作用机制的研究进展

乳酸杆菌作为益生菌广泛用于人和动物。本文综述了乳酸杆菌改善宿主健康的机制。乳酸杆菌可通过产生抗菌物质如乳酸、过氧化氢、细菌素,或者通过竞争营养或肠道黏附位点来抑制致病菌;通过诱导黏附素的分泌或阻止细胞凋亡而增强肠道的屏障功能,从而保护肠道。文章重点讨论了乳酸杆菌表面成分（表面蛋白、脂磷壁酸和肽聚糖）与肠道受体（Ｃ型凝集素受体、Ｔｏｌｌ样受体和 Ｎｏｄ样受体）,阐述了他们结合后启动免疫调节信号,调控肠道免疫功能以发挥改善健康作用的机制。     

中华人民共和国农业部公告 第267号

为贯彻落实《兽药生产质量管理规范》(简称《兽药GMP》),进一步推动兽药GMP实施进程,我部制定了《兽药生产质量管理规范检查验收办法》,现予公告。本公告自2003年6月1日起施行。附件:兽药生产质量管理规范检查验收办法二○○三年四月十日第一章 总则 第一条 为推动《兽药生产质量管理规范》(以下简称兽药GMP)的实施,规范兽药GMP检查验收工作,制定本办法。 第二条 农业部负责全国兽药GMP管理和检查验收工作;负责制修订兽药GMP检查验收管理规定;负责兽药GMP检查员队伍建设和监督管理工作,负责国际兽药贸易中GMP互认工作。 …     

鸡败血支原体垂直传播模式及其阻断方法

以国际标准强毒Ｒ株人工感染非免疫产蛋鸡,定时扑杀,分别从鼻窦、眶下孔、气管、肺、气囊、卵巢和输卵管分离ＭＧ,并收集感染鸡所产蛋分离ＭＧ。结果表明,人工感染４８小时后上、下呼吸道及肺已被全面感染,９６小时气囊已被感染,１２０小时输卵管已能分离到ＭＧ,卵巢始终分离不到ＭＧ。人工感染鸡自１４４小时便能在其所产蛋中分离出ＭＧ。药物治疗能在７２小时内消除感染,油乳剂苗则需２４天后逐渐降低蛋内ＭＧ分离率,药物卵内注射、种蛋药浴、高温处理均能杀死卵内ＭＧ,但以研制的种蛋浸泡剂药浴效果为最好。     

Effects of size of ingestively masticated fragments of plant tissues on kinetics of digestion of NDF

Ingestively masticated fragments were collected and sized via sieving. Different sizes of esophageal masticate and ruminal digesta fragments, and ground fragments of larger masticated pieces were incubated in vitro, and undigested NDF remaining at intervals of up to 168 h of incubation was determined. The ruminal age-dependent time delay (tau) for onset of digestion of NDF was positively correlated (P < 0.004) with the mean sieve aperture estimated to retain 50% of the fragments between successive sieve apertures (MRA). Degradation rate of potentially degradable NDF (PDF) and level of indigestible NDF were not related (P > 0.10) to MRA of masticated and ground fragments. Estimates of tau were positively related to MRA, with slopes of bermudagrass < corn silage < ruminal fragments of corn silage. It was concluded that fragment size-, and consequently, ruminal age-dependent onset of PDF degradation of a mixture of different fragment sizes results in an age-dependent rate of degradation of the more rapidly degrading of two subentities of PDF. Models are proposed that assume a tau before onset of simultaneous degradation of PDF from two pools characterized as having gamma-modeled age-dependency and age-constant rates. The ruminal age-dependent pool seems to be associated with the faster-degrading pool, and its rate parameter increases with range in MRA in the population of fragments. Conceptually, the ruminal age-dependent rate parameter for PDF degradation seems to represent a composite of several effects: 1) effects of the size-dependent tau; 2) range in MRA of the population of ingestively masticated fragments; and 3) subentities of PDF that degrade via more rapid age-dependent rates compared with subentities of PDF that degrade via age-constant rates. The estimated fractional rates of ruminative comminution of ingestively masticated fragments (0.060 to 0.075/h) were of a magnitude similar to the mean fractional rates of PDF digestion (0.030 to 0.085/h), which implies that ruminative comminution may be first-limiting to fractional rate of PDF digestion. The in vivo roles of ingestive and ruminative mastication of fragments on PDF degradation must be considered in any kinetic system for estimating PDF digestion in the rumen. These results and others in the literature suggest that the rate of surface area exposure rather than intrinsic chemical attributes of PDF may be first-limiting to degradation rate of PDF in vivo.