共查询到19条相似文献,搜索用时 46 毫秒
1.
2.
3.
<正> 犬肉毒梭菌毒素中毒在临床上极少见,笔者曾遇见两例,现报道如下:1 临床症状病初站立不稳,步态螨跚,随着病情的发展,以后肢到前肢发生进行性瘫痪,针刺反应减弱。病犬精神不振,食欲废绝,口角流有泡沫唾液,两耳下垂,眼结膜潮红,视力减退,反应迟钝,呼吸急促,心跳加快,节 相似文献
5.
6.
7.
8.
5月26日,我们接到一个以吃食了大量死鸭肚里的蛆而发生死亡散养产蛋鸡病例。经剖检发现嗉囊内有大量死蛆,疑为肉毒梭菌毒素中毒,后通过成功的处理措施,病情能 相似文献
9.
谈肉毒中毒的病因与蜂蜜〔美国〕比特尔斯通,F.什么是肉毒中毒?肉毒中毒是由一种叫做肉毒杆菌的细菌所引起的,这种菌存在于土壤中。肉毒杆菌素不会引起胃肠道的炎症。但是,如该毒素被神经吸收,会对植物神经末梢产生一种不可逆的作用,使运动神经不能促使肌肉兴奋。... 相似文献
10.
肉毒毒素是由厌氧的肉毒梭菌在生长繁殖过程中产生的一种细菌外毒素,能引起动物发生肉毒中毒。根据毒素抗原性的不同,可将肉毒梭菌及其毒素分为A、B、C、D、E、F和G型7个型。其中A、B、E及F型为人的中毒型别,C和D型为动物的中毒型别。C型肉毒梭菌在自然界广泛分布,饮食被C型肉毒梭菌特别是C型肉毒毒素污染的水或草料的动物有可能发生C型肉毒中毒。 相似文献
11.
Tore Bjarne Tjaberg 《Acta veterinaria Scandinavica》1973,14(1):193
The present investigation was carried out in order to find a suitable medium for the production of proteolytic enzymes from different types of Clostridium botulinum. Proteolytic activity was found in Clostridium botulinum types A, B, C, D and F, while supernatants of Clostridium botulinum type E did not possess any proteolytic activity at all.Skim milk medium possessed the greatest ability for the production of proteolytic enzymes from the different cultures of Clostridium botulinum tested, while Robertson’s meat broth produced lowest amounts. Highest titres were usually found after 4–5 days of incubation and, after this period, the level of proteolytic activity decreased. 相似文献
12.
13.
14.
T B Tjaberg 《Acta veterinaria Scandinavica》1974,15(4):487-506
In this study the influence of bovine serum protease inhibitors, trypsin and proteases produced by different types of Clostridium botulinum has been investigated. Trypsin and botulinum proteases had the capability of increasing the toxicity in growing cultures in Clostridium botulinum types A, B and E. Trypsin increased the toxin level to a greater extent than proteases from Clostridium botulinum types A, B, C and F. Protease inhibitors did not influence the toxin formation to any extent compared with the controls. The combined effects of proteases and protease inhibitors on the development of toxin in Clostridium botulinum type B were also investigated by adding proteases and protease inhibitors to the same culture at different time intervals. Protease inhibitors did not reduce the toxicity of the cultures as compared to the controls. Altogether a complex relationship seems to exist between protoxin, toxin, proteases and inhibitors in the culture, and the order and time sequence of addition seem to be of importance. The results obtained in this investigation indicate that proteases of Clostridium botulinum play a part in the formation and/or activation of toxin in growing cultures of proteolytic strains such as Clostridium botulinum types A and B. As to the activation of protoxin and progenitor toxin produced by non-proteolytic Clostridium botulinum types B and E, botulinum proteases showed a marked capability of increasing the toxicity in these cultures. Trypsinization may be valuable for the detection of Clostridium botulinum types A and B in foods, as well as for type E, where it is commonly used. 相似文献
15.
产气荚膜梭菌主要致死性毒素的研究进展 总被引:3,自引:0,他引:3
产气荚膜梭菌作为危害各国家畜养殖业的主要致病菌之一,受到国内外研究者的普遍关注.产气荚膜梭菌的主要致病因子是菌体产生的外毒素.近年来,国内外对其致病机理进行了深入研究,建立起简便、快速的检测方法,并且在防治手段方面取得了巨大突破.对产气荚膜梭菌的主要致死性毒素类型、致病机理、检测技术及其防治措施等方面的研究进展进行了阐述. 相似文献
16.
Prévot V Tweepenninckx F Van Nerom E Linden A Content J Kimpe A 《Zoonoses and public health》2007,54(8):320-327
Botulism is a rare but serious paralytic illness caused by a nerve toxin that is produced by the bacterium Clostridium botulinum. The economic, medical and alimentary consequences can be catastrophic in case of an epizooty. A polymerase chain reaction (PCR)-based assay was developed for the detection of C. botulinum toxigenic strains type C and D in bovine samples. This assay has proved to be less expensive, faster and simpler to use than the mouse bioassay, the current reference method for diagnosis of C. botulinum toxigenic strains. Three pairs of primers were designed, one for global detection of C. botulinum types C and D (primer pair Y), and two strain-specific pairs specifically designed for types C (primer pair VC) and D (primer pair VD). The PCR amplification conditions were optimized and evaluated on 13 bovine and two duck samples that had been previously tested by the mouse bioassay. In order to assess the impact of sample treatment, both DNA extracted from crude samples and three different enrichment broths (TYG, CMM, CMM followed by TYG) were tested. A 100% sensitivity was observed when samples were enriched for 5 days in CMM followed by 1 day in TYG broth. False-negative results were encountered when C. botulinum was screened for in crude samples. These findings indicate that the current PCR is a reliable method for the detection of C. botulinum toxigenic strains type C and D in bovine samples but only after proper enrichment in CMM and TYG broth. 相似文献
17.
Vegetative cells and spores of Clostridium botulinum type B and E were inoculated into salami sausages with and without the preservatives sodium nitrite and sodium benzoate. The growth and toxin production of Clostridium botulinum type B and E were inhibited in this type of salami sausages, even without any addition of preservatives. The use of a starter culture with pH-lowering components has both technological and hygienic advantages. 相似文献
18.
By the use of the electrophoretic casein precipitating inhibition test (CPI-test) the serological relationship between proteolytic enzymes produced by different species within the genera Clostridium and Bacillus has been tested. The proteases produced by Clostridium botulinum types A, B, C, D and F cross-reacted with each other. Clostridium botulinum strain 84 was inhibited by antiproteases produced against Clostridium sporogenes, Clostridium botulinum types C and F (protease F I and F II), but not by antiproteases against Clostridium botulinum types B and F (protease II), Clostridium bifermentans and Clostridium perfringens. The protease of the newly described Clostridium botulinum strain 89 (type G) was inhibited by Clostridium sporogenes antiprotease, but not by any of the other antiproteases. It is not possible to differentiate between Clostridium botulinum, Clostridium sporogenes and Clostridium perfringens by use of serological differentiation of their proteolytic enzymes. The protease of Clostridium bifermentans is not serologically related to any of the species tested in this investigation. Proteases produced by different Bacilli were not inhibited by antiproteases from Clostridium botulinum types B, C and F, Clostridium sporogenes, Clostridium bifermentans, and the two strains of Clostridium perfringens tested. This investigation indicates a serological relationship between proteases from different Clostridium species, but not a serological relationship between proteases produced by the Clostridium species and Bacillus species tested. 相似文献
19.
Kristine Gismervik Torkjel Bruheim Liv M R?rvik Solveig Haukeland Ida Skaar 《Acta veterinaria Scandinavica》2014,56(1)