共查询到7条相似文献，搜索用时 11 毫秒
1.
2.
H. Fieten V.C. Biourge A.L. Watson P.A.J. Leegwater T.S.G.A.M. van den Ingh J. Rothuizen 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2015,29(3):822-827
Background
Genetic and environmental factors, including dietary copper intake, contribute to the pathogenesis of copper‐associated hepatitis in Labrador retrievers. Clinical disease is preceded by a subclinical phase in which copper accumulates in the liver.Objective
To investigate the effect of a low‐copper, high‐zinc diet on hepatic copper concentration in Labrador retrievers with increased hepatic copper concentrations.Animals
Twenty‐eight clinically healthy, client‐owned Labrador retrievers with a mean hepatic copper concentration of 919 ± 477 mg/kg dry weight liver (dwl) that were related to dogs previously diagnosed with clinical copper‐associated hepatitis.Methods
Clinical trial in which dogs were fed a diet containing 1.3 ± 0.3 mg copper/Mcal and 64.3 ± 5.9 mg zinc/Mcal. Hepatic copper concentrations were determined in liver biopsy samples approximately every 6 months. Logistic regression was performed to investigate effects of sex, age, initial hepatic copper concentration and pedigree on the ability to normalize hepatic copper concentrations.Results
In responders (15/28 dogs), hepatic copper concentrations decreased from a mean of 710 ± 216 mg/kg dwl copper to 343 ± 70 mg/kg dwl hepatic copper after a median of 7.1 months (range, 5.5–21.4 months). Dogs from a severely affected pedigree were at increased risk for inability to have their hepatic copper concentrations normalized with dietary treatment.Conclusions and Clinical Importance
Feeding a low‐copper, high‐zinc diet resulted in a decrease in hepatic copper concentrations in a subset of clinically normal Labrador retrievers with previous hepatic copper accumulation. A positive response to diet may be influenced by genetic background. Determination of clinical benefit requires further study. 相似文献3.
J.H. Vos T.S.G.A.M. van den Ingh W. Misdorp R.F. Molenbeek F.N. van Mil G.R. Rutteman 《The Veterinary quarterly》2013,33(3):102-107
Summary Normal canine mammary gland tissue was studied immunohistochemically with monoclonal antibodies (MoAbs) directed against various human keratin types, vimentin, desmin, and α‐smooth muscle actin. Both ductal and alveolar luminal cells were immunoreactive with MoAbs recognizing respectively human keratins no. 7, 8, 18 and 19. In addition, some ductal luminal cells were labelled with a keratin 4 and a keratin 10 MoAb. Basal/myoepithelial cells were immunoreactive only with MoAbs directed against keratin 14, keratins 14 and 17, and a‐smooth muscle actin. The vimentin MoAb merely labelled solitary loose intraluminal cells representing macro‐phages or sloughed epithelial cells. These findings correspond largely to observations made in human breast tissue. 相似文献
4.
The diagnosis and treatment of a case of crimidine poisoning in a dog are described. Presenting signs were seizures and vomiting. The vomitus contained a purple coloured cereal grain. The signs and grain colour were suggestive for a rodenticide with convulsive effects The diagnosis of crimidine poisoning was made by thin layer chromatography and was later confirmed by finding the source of the poison. Except for the administration of Vit B6, the specific antidote for crimidine, general treatment principles for poisoning were followed. The treatment of crimidine poisoning is time consuming and requires intensive care facilities. 相似文献
5.
J.W. Schrama W. van der Her J. Gorssen A.M. Henken M.W.A. Verstegen J.P.T.M. Noordhuizen 《The Veterinary quarterly》2013,33(3):90-95
Summary Conditions (total complex of stressors) during the transport of animals vary strongly between and within transports. Adverse climatic conditions are stressors that animals have to face during transport. The thermoregulation of animals is discussed with respect to threshold values for optimal climatic conditions. These thermal thresholds depend on animal related factors and environmental conditions. The specific impact of transport conditions, such as food and water deprivation, high stocking density, high humidity and high air velocity, on thermal thresholds are described. 相似文献
6.
Summary A modified technique for transposition of the internal obturator muscle was used to repair perineal hernias in 100 dogs. Complications and long‐term results are described. The most important complications were wound infection (45%), faecal incontinence (15%), and perineal fistula (7%). These complications often occurred in combination. The recurrence rate of perineal hernia was 5%. Nine of the 15 patients with faecal incontinence had paresis of the external anal sphincter or faecal incontinence before surgery. We suggest that in numerous patients, faecal incontinence is a complication of the condition rather than a complication of treatment. The owner's assessment of the surgical result was good in 71% and moderate in 18% of the cases. 相似文献
7.
C. D. W. König 《The Veterinary quarterly》2013,33(3):127-130
The occurrence of keratoconjunctivitis infectiosa ovis (KIO) in the Netherlands was reported by Holland et al. in 1969 for the first time. At present the disease is well known in the Netherlands. Nevertheless there are still questions about the causative agent and the most effective and easiest therapy. Most authors suppose that the disease is caused by Colesiota conjunctivae, although others mention infections by other chlamydia, Mycoplasma conjunctivae, Mycoplasma ovipneumoniae, Acholeplasma oculi and a wide variety of bacteria. The diagnosis can be made on the basis of the symtoms and the detection of the agent in Conjunctival scrapings. The bacilliform bodies can be found in conjunctival smears in the cytoplasm (Giemsa, Stamp). Many therapies are used topically, parenterally or orally. Locally used eye‐ointments must be effective against Colesiota; antimicrobial drugs administered by injection must be effective against the latter and also provide a sufficient cell tissue penetration with excretion into the lacrimal fluid. Injections have proved to be easier to administer, especially in serious outbreaks, but such outbreaks are exceptional (18). Some therapies have been evaluated in small scale experiments (28) as well as in field trials (17). 相似文献