Suspected Albuterol Intoxication In A Dog

A suspected case of intoxication of a dog by the beta₂-adrenergic agonist albuterol is discussed. Clinical abnormalities observed included hypokalemia, weakness, tachycardia, tachypnea, hyperthermia, and delirium. Treatment with high-dose potassium supplementation helped to resolve these abnormalities.
Adrenergic control of potassium homeostasis is beta₂-mediated and causes the intracellular uptake of potassium, primarily in liver and muscle. The mechanism of action of albuterol in decreasing serum potassium, its clinical applications in humans, and possible application in dogs are discussed.     

Suspected Tension Pneumomediastinum In A Dog: A Case Report

Successful resuscitation of a trauma-induced, suspected tension pneumomediastinum in a dog is presented. The cause was a caudal cervical penetration wound which acted as a one-way valve allowing air to enter, but not exit, the cranial mediastium. Early in the course of hospitalization, respiratory and cardiovascular collapse occurred; an emergent parasternotomy allowed decompression of the mediastinum, and the cradiovascular system immediately responded. The dog made a complete recovery following surgical exploration and removal of contaminated mediastinal tissue. Nine days of intensive care included 24-hour monitoring, oxygen therapy, intravenous crystalloids and colloids, continuous pleural suctioning, nutritional support, antibiotics, and pain control.     

A New Look at Developmental Subluxation and Dislocation: Hip Dysplasia in the Dog

Abstract— For the past three years the condition of hip dysplasia in dogs has been investigated. Over 200 dogs have been radiographed, dissected and compared both macroscopically and histologically. Both normal and dysplastic pups have been followed from birth to maturity with daily X-rays and finally the animals were euthanized, dissected, and the tissues sectioned. An analysis of these observations are reported.     

犬有机磷中毒的实验室诊断

20 0 1年 4月份 ,延边大学农学院动物医学系动物医院接到龙井市的 1例病例 ,根据临床症状、病理变化及实验室诊断最终确诊为有机磷中毒 ,现将诊断的具体情况报道如下。1　发病情况吉林省龙井市某单位养警犬已多年 ,在 2 0 0 1年 4月 17日晚畜主发现有 1条警犬突然发病 ,不到 1ｈ即倒地死亡 ,据畜主所述 ,在发病前所养的警犬没有异常变化 ,发病后就突然死亡。2　临床症状及剖检变化2 .1　临床症状主诉 :最先出现高度兴奋、惊恐、乱跑以及精神过敏、流涎等现象 ,继而出现精神沉郁 ,发生呕吐、腹痛和腹泻、呼吸困难、粪便中含有血液 ,后期全身…     

A Model For Prediction Of Survival In Critically III Dogs

A system was developed for objective prediction of survival, which could be applied to all critically ill patients, regardless of disease, at an early stage of hospitaluation. Such a system would allow risk assessment of groups for experimental studies according to probability of survival and it might allow us to avoid expenditure of scarce clinical resources on animals with little chance of survival. The prospective study included 200 critically ill dogs: 93 females and 107 males, representing 62 breeds. With survival defined as alive 30 days after admisssion to ICU the overall mortality rate was 40.5% (81 of 200 dogs). Data collected included signalment and parameters that reflected vital organ function, the severity of physiologic derangement and the extent of physiologic reserve. We recorded the most abnormal value for each parameter within 24 hours of admission to ICU and logistic regression analysis was used to analyze four different weighting systems. The best model had a concordance 0f 86.5% with outcome, and it was then re-evaluated to determine whether individual variables could be eliminated without losing predictive accuracy. Fourvariables were eliminated, resulting in a final model with 18 variables which had 86.3% concordance with outcome. At a 0.5 cut-off for predicted risk, the model had sensitivity Of 69%, specificity ficity of 86% and positive predictive value of 77%. A Receiver Operating Curve was constructed using serial cut-offs for predicted outcome from 0.1 to 0.9, and the area under the curve was 0.89. Thus, an equation was generated that gives an estimate of the probability of survival.     

家禽铜营养研究进展

铜是家禽的必需微量元素之一，在动物体内发挥重要的作用。Braude（1945）首次发现日粮中添加高铜，可明显提高猪的生产性能，后来许多研究者证明在饲料中添加铜后可增加养猪效益，随后广泛应用在猪生产上。其后在生长鸡和蛋鸡上也观察到铜的促生长作用，不但可以降低鸡蛋和肉品中脂质、增加禽产品质量，而且可以提高鸡的免疫力。铜在维持生产性能、增强机体抵抗力、机体造血等方面有不可替代的作用。本文从铜的生物学功能、缺乏和过量、补加形式、补加剂量四个方面进行综述。     

犬胃内异物及其诊治

哈尔滨铁路兽医段年平均检疫与发运各种犬约几万条。为了贯彻“预防为主 ,防重于治”的原则 ,尽力完成运前犬病的检疫工作 ,于 2 0 0 0～ 2 0 0 2年期间 ,我们与哈尔滨市马氏宠物医院高级兽医师马宗禹先生共同合作 ,对道外区宠物市场犬的胃内异物诊治进行了综合性普查。胃内异物是犬的常发病。近年来 ,我们在动物门诊共遇到19例犬的胃内异物病例 ,其中因异嗜造成的胃内异物 16例 ,异物为毛团 7例、塑斜布 2例、骨头 5例、尼龙袜 1例、无机物沉积形成的胃结石者 1例 ;因犬衔咬物品玩耍而误咽造成的胃内异物或吃较大块食物时受到突然剌激而咽…     

A Scanning Electron Microscopy Study of Frozen / Thawed Dog Sperm During In Vitro Gamete Interaction

The aim of this work was to study the effects of cryopreservation on the binding and penetration of dog spermatozoa to the zona pellucida (ZP) by scanning electron microscopy (SEM). The sperm-rich fraction of six ejaculates from five dogs was divided into two aliquots and washed by centrifugation. One aliquot was processed as fresh control sample and the other aliquot frozen in Tris-fructose extender. Gamete interaction was assessed using in vitro matured bitch oocytes, which were co-incubated for up to 3 h. At hourly intervals after the start of co-incubation, in vitro fertilized (IVF) oocytes were processed by SEM. The results were analysed statistically using the anova test. Differences in binding and penetration of the spermatozoa to the ZP occurred; a lower proportion of oocytes with spermatozoa bound to ZP was observed using frozen sperm (p < 0.05) than with fresh sperm (61%, 57% and 53% vs 42%, 40% and 44% at 1, 2 and 3 h, respectively). The percentage of ZP penetration by fresh sperm was directly proportional to the time of co-incubation (9%, 25% and 34%; p < 0.05); in contrast, no differences were observed in the penetration rate with frozen-thawed sperm (21%, 17% and 21%). More acrosome reacted sperm were observed in frozen sperm than in fresh sperm on the surface of the ZP. The differences in the percentage of binding and penetration between fresh and frozen sperm during the co-culture could indicate that the time course of penetration is faster in frozen-thawed dog spermatozoa than in fresh sperm, but that fresh spermatozoa can penetrate more oocytes over a given period of time, which may be related to their reacted or non-reacted initial status.     

Evalution of Age as a Risk Factor For Perianesthetic Morbidity and Mortality in the Dog

This study was intended to determine if age is a risk factor for perianesthetic morbidity/mortality in dogs and to identify other factors that may be important. A prospectivecohort study compiled data from 942 dogs (477 females; 465 males) ≥6 months undergoing inhalation anesthesia for≥30 minutes. were included. Serious perianesthetic complications occurred in 79 dogs. Logistic regression used a final model contanining age and ASA grade and showed a significant estimated odds ratio (O) for old vs young or middle-aged dogs of 1·89 (95% CI: 1·05,3·38). The Ofor ASA grade increased significantly with grade — ASA grade 3:1or2 = 3.4, ASA grade 4:1or2 = 7·1, and ASA grade 5:1or2 =18·8. Thus, old dogs were nearly twice as likely to develop serious perianesthetic complications, even when accounting for ASA grade. However, conditions that increased ASA assessment by one grade had more impact on increasing the likelihood of serious perianesthetic complete.