生物敷料对大鼠深Ⅱ度烧伤创面愈合的作用

为了评价生物敷料对烧伤创面的治疗效果，将SPF猪皮细化处理后制成软膏制剂，以其作为生物敷料对大鼠深Ⅱ度烧伤进行了治疗试验，对照组采用普遍油纱布敷料处理，观察烧伤大鼠创面愈合程度，记录愈合时间，并测定了大鼠在烧伤前后的血液学指标。结果显示，试验组比对照组创面愈合时问短，愈合率高，血液学指标恢复较快。     

Effect of a hydrocolloid dressing on first intention healing surgical wounds in the dog: a pilot study

OBJECTIVES: To evaluate the efficacy of a hydrocolloid dressing for the treatment of surgical wounds in dogs. METHODS: Six healthy young female dogs of medium size and different breed underwent ovariohysterectomy. Histological evaluation was performed on biopsies taken from the edges of the wounds at day 7. The dressing was applied on one half of the wound according to manufacturer's instructions; the second half served as control. Biopsy specimens were fixed in a 10% formalin buffered solution pH 7.4, paraffin embedded and stained with haematoxylin and eosin. For clinical assessment, the presence and quality of exudate, erythema of the surrounding area, swelling and correct apposition of the wound margins were evaluated. RESULTS: The hydrocolloid dressing was easy to use. The clinical quality of the treated skin wounds was superior to the non-treated ones. Comparison of histological features between treated and untreated wounds showed a more regular organisation of the granulation tissue in the treated wounds, with fibroblasts being aligned parallel to the overlying epidermis. The number of inflammatory cells and the extension of granulation tissue were less prominent and less widespread in treated compared to untreated wounds. CONCLUSION: The dressing performed very well in terms of adhesiveness and flexibility. It was useful in the management of surgical wounds to avoid contamination and ameliorate the epithelialisation rate and granulation tissue morphology of the surgical scar.     

A Novel Bioelectric Device Enhances Wound Healing: An Equine Case Series

The use of low-level microcurrents for accelerated wound healing is well documented. A case series was conducted to assess wound healing outcomes following the application of a wireless, current-generating bioelectric wound care device in 10 equines that presented with traumatic injuries in the lower extremity. Wounds were treated with a bioelectric device held in place with standard bandaging twice a week. At each follow-up visit, wounds were photographed and assessed for signs of epithelialization. All presented wounds were reduced in size or achieved complete wound closure, with an average 1.3% wound healing per day. The results of this case series demonstrate the safety and efficacy of a bioelectric device as a management option for traumatic lower-extremity wounds in equines and hold significant promise in promoting enhanced healing rates and improved aesthetic outcomes.     

蚕蛹壳聚糖复合水凝胶的抗菌性能及对创伤的愈合作用

以蚕蛹壳聚糖、蜂蜜和明胶等为基质制备医用复合水凝胶。对以不同配比制备的蚕蛹壳聚糖复合水凝胶、单纯蚕蛹壳聚糖水凝胶、蜂蜜水凝胶的抗菌性能进行比较试验,并以大耳白兔为受试动物,采用切片法检测蚕蛹壳聚糖复合水凝胶对烫伤伤口的愈合作用。结果表明:用质量分数为0.25%的蚕蛹壳聚糖和质量分数为20%的蜂蜜制成的复合水凝胶的杀菌作用明显高于市售烧伤膏和单纯蚕蛹壳聚糖或蜂蜜水凝胶,对金黄色葡萄球菌、大肠杆菌24 h内的抑菌率均达到100%,且持久性好;大耳白兔烫伤伤口经0.25%蚕蛹壳聚糖+20%蜂蜜复合水凝胶处理后12 d可基本愈合,切片观察愈合的伤口表皮无溃疡,局部毛囊增生,且有新生表皮细胞生成。研究结果显示,蚕蛹壳聚糖复合水凝胶具有广谱抗菌性能,可用作创伤敷料。     

一种新型伤口处理剂对仔猪去势伤口处理的效果实证

在猪场中,正确的伤口处理对于伤口的恢复具有重要的意义。为了研究新型伤口处理剂对仔猪去势伤口的效果,特选取5～7日龄533头公仔猪,分为两组。试验组利用常规碘酊消毒去势后喷洒新型伤口处理剂,对照组则按常规操作单纯碘酊消毒。而后分别记录每天伤口恢复情况以及去势后15 d内表现关节肿的去势公仔猪比例。结果表明:新型伤口处理剂可以减少伤口出血,促进去势伤口的愈合,减少细菌通过伤口感染猪只的几率。     

紫花苜蓿根瘤菌种子处理剂的研究

研究不同拌种处理对紫花苜蓿(Medicago sativa)的影响,结果表明:室内与室外盆栽发芽结果基本一致,发芽率都没有明显提高;在苜蓿分枝期拌种处理的结瘤数和鲜重都有不同程度的增加,根瘤数量提高21.7%-232%,鲜重增加了3.7%-25.4%,光合速率和蒸腾速率略低于对照;苜蓿种子处理剂活菌量(CFUml^-1)跟踪监测结果表明,S型最适合活菌保存,在常温保存条件(20-30℃)优于4℃保存。     

Evaluasie van verskillende grasspesies vir moontlike gebruik in die stabilisering van kunsmatige waterbane

Digitaria eriantha subsp. pentzii (= D. decumbens), Cynodon nlemfuensis en “Coastcross II” (Cynodon‐Hibried) was met behulp van steggies gevestig is, en Chlorisgayana. Pennisetum clandestinum en Cynodon dactyton (Pasto Rico), wat met behulp van saad gevestig is, het die beste bedekkings‐waarde gedurende die seisoen van vestiging gelewer. Van die voormelde spesies het die basale bedekking van Chloris gayana, Pennisetum clandestinum, Cynodon dactylon (Pasto Rico) en Digitaria eriantha subsp. pentzii ( = D. decumbens) gedurende die vier jaar wat die proef geduur het, na bevredigende aanvanklike bedekking, toegeneem of minstens konstant gebly. Die beste vestiging is gedurende Desember verkry, terwyl aangetoon is dat ‘n bemesting van ten minste 120 kg N + 16 kg P/ha nodig is om ‘n goeie bedekking en produksie per ha gelewer.     

壳聚糖生物敷料的研究现状及其发展前景

文章通过简要介绍壳聚糖的优良特性,综述了壳聚糖在创伤敷料方面的研究进展,指出了不同类型壳聚糖敷料的制备方法及其优缺点。简要分析了当前的市场环境,表明壳聚糖敷料具有广阔的应用前景。