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1.
Perforating ulceration of the small intestine was diagnosed in 5 adult horses. Affected horses presented with signs of low‐grade colic, depression and inappetance. Abdominal paracentesis yielded abnormal peritoneal fluid in all cases. Perforating ulcers were located at the mesenteric border in 4 horses and the ileum in one horse. All horses had diffuse septic peritonitis. The aetiology of the condition is unknown. 相似文献
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I R Hart 《Research in veterinary science》1979,27(3):269-274
Peroxidase conjugated antisera to canine immunoglobulins G and A and to human immunoglobulin M, have been used to study the distribution of immunoglobulin-containing cells in the small intestine of the young and adult dog. At all levels of the small bowel of the adult dog, IgA:IgM:IgG cells have a 2:1:1 ratio while the greatest number of immunocytes is found in the duodenum and decreases towards the distal portion of the small intestine. The young puppy shows a predominance of IgM-containing cells in the small intestinal lamina propria during early life but the adult pattern of immunocyte distribution has been achieved by weaning. 相似文献
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During a 10 year period. 20 dogs with primary localized neoplasia of the small intestine were presented at the University of Bristol Veterinary School. Half the tumours were carcinomas, the remainder being lymphosarcomas (5 cases), leiomyosarcomas (3 cases) and leiomyomas (2 cases) Lesions occurred at a variety of locations along the tract, but descending duodenum (6 cases) and terminal ileum (4 cases) were the commonest sites. Clinical findings varied. All dogs except three presented with chronic illnesses, but only seven showed signs immediately referable to alimentary tract disease. Abnormalities were found at radiographic examination in all cases except one and provided or confirmed the indication for laparotomy. Ten animals were destroyed at the time of surgery, two died during the immediate post-operative period and three were later destroyed because of suspected recurrence. Four dogs are reported well at intervals of between nine months and two years following surgery. 相似文献
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M D Willard J E Cook L S Rodkey A D Dayton N V Anderson 《American journal of veterinary research》1978,39(9):1502-1505
Biopsies of small intestine from 7 dogs were examined by fluorescence microscopy to determine the number of IgM-containing cells in the lamina propria. Biopsies were taken from duodenum, jejunum, and ileium. (Cell counts were made by 2 persons to demonstrate reproducibility.) There were 452.24 +/- 60.09 cells per mm2 in the duodenum 572.68 +/- 62.13 cells per mm2 in the jejunum, and 107.47 +/- 59.57 cells per mm2 in the ileum. All sections were cut at 6 micrometer. The ileum had fewer cells than either duodenum or jejunum (P = 0.000038 and 0.00001, respectively), whereas duodenum and jejunum did not differ significantly in numbers of cells (P = 0.17528). Quantifying autofluorescent cells in the same sites showed no significant differences among the 3 tissues (P = 0.24697). The autofluorescent cells differed in intensity and morphology from the IgM cells. These two observations tend to support the contention that the autofluorescent cells did not bias the IgM cell counts at the 3 sites. Total autofluorescence (cells, collagen, and vessels) was higher in the ileum than in either the jejunum or the duodenum (P = 0.04967 and 0.03050, respectively). However, all 3 categories counted (IgM cells, autofluorescent cells, and autofluorescent structures) had significant dog-tissue interactions. This will necessitate determining normals for each age-sex-breed category of dog studied. 相似文献
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Gnotobiotical one-day-old piglets were infected with 100,000 Isospora suis coccidia oocysts, and were immediately killed. In piglets killed on the 3rd to 11th day after infection (DAI), the morphometric analysis of alkaline phosphatase activity was performed in the area of the microvillus zone of small intestine. In the control 2-7 days old animals, the small intestine was not equally supplied with alkaline phosphatase. In duodenum the activity reached 88.37 per cent of the active length of absorbent surface (% LAac), in the middle jejunum 95.98 per cent LAac, in the dorsal jejunum 78.63% LAac and the ileum 90.55 % LAac. The width of the active area was more balanced and ranged from 5.003 microM in the ileum to 6.129 microM in the dorsal jejunum. In infected gnotobiotical piglets the lowest activity was found out on the 3rd to 4th DAI, with a greater decline on the 9th day after infection. The range from 25.99 to 40.50 per cent LAac with minimum in the duodenum and maximum in the ileum was observed on the 3rd DAI. In the middle and dorsal ileum the activity was nearly equal (28.34 and 27.69 per cent LAac). nI the dorsal jejunum a moderate increasing was up to 47.13% LAac on the 4th DAI, with the exception of the ileum, where the activity of alkaline phosphatase decreased to 24.96% LAac. On the 9th DAI the activity of alkaline phosphatase was nearly equal in the whole small intestine (from 55.70 to 60.01% LAac) with the maximum in the middle jejunum. In the width of the reaction product a direct dependence on the total activity of alkaline phosphatase was evident only in the segment of the middle and dorsal jejunum and ileum, but merely on the period of the 3rd to 4th DAI. The lowest values were measured in the middle jejunum (0.982 micron on the 3rd DAI and 0.709 micron on the 4th DAI). No dependence was observed between the total activity and the reaction product in the middle jejunum (0.982 micron on the 3rd DAI and 0.709 micron on the 4th DAI), there was no general stabilisation of the activity of alkaline phosphatase. 相似文献
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Objective To evaluate the visibility of various portions of the small intestine in healthy horses using capsule endoscopy. Procedure Six healthy, conscious adult Thoroughbreds were restrained and an endoscopic capsule (PillCam® SB capsule) was inserted into the oesophagus using an intranasal catheter aided by a guide wire. Water (500 mL) flushed the capsule down the gastrointestinal tract. Data were collected and stored in the recorder of the endoscopic system for 6 hours after capsule insertion and the images were evaluated using an image reader and scored using a visual analogue scale. Results Capsule endoscopy enabled observation of the distinct mucosal shape, colour, and villus structure of the intestinal lumen from the duodenum through the proximal jejunum. At 4 h after passing the pylorus, the endoscopic capsule started transmitting increasingly dark images in the distal jejunum as the lumen circumference increased. Means of the visual analogue scale in the duodenum, proximal jejunum, and distal jejunum were 93.8 ± 1.3%, 86.2 ± 2.5% and 48.8 ± 6.3%, respectively. Differences among these values were statistically significant (P < 0.05). Conclusions and Clinical Relevance Capsule endoscopy enables observation of the distinct mucosal shape, colour and villus structure of the proximal and mid-small intestine in healthy horses. 相似文献
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The ultrastructural appearance at primary and metastatic sites of ten ovine small intestinal adenocarcinomas was that of scirrhous tubular adenocarcinoma. Polygonal undifferentiated tumor cells had desmosomes, folded nuclei, and moderate numbers of mitochondria but few other organelles. More differentiated cells were columnar with apical microvilli and basal nuclei. They contained granular endoplasmic reticulum, Golgi and secretory granules. Microvillus-lined intracytoplasmic lumina (5-10 micron diameter), fibrous filaments (10 nm diameter, up to 1.4 micron length) and tubular paracrystalline arrays (hexagonal symmetry, 37-nm periodicity) in lumina and secretory granules were seen in some tumor cells in all ten sheep. 相似文献
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The pancreatic beta-cell volume was assessed in 12 clinically normal crossbred dogs using immunohistochemical labelling for insulin and computer-assisted morphometric analysis. The beta-cell volume was less in the right lobe compared with the body and left lobe, but the beta-cell volume did not differ between the body and the left lobe as reported previously. The use of immunohistochemistry, computer-assisted morphometry, the inclusion here of extra-islet beta-cells and the exclusion of non-beta-endocrine cells in the investigation of the beta-cell volume may have contributed to this discrepancy. As most beta-cells form irregularly shaped three-dimensional bodies (islets of Langerhans), the effect of the plane of tissue transection (sagittal, transverse, oblique) on the calculation of the beta-cell volume was also examined. The beta-cell volume in the sagittal plane of the right lobe was lower than the volume in the oblique plane of the same lobe but was not different from the volume in the transverse plane. However, there were no differences in beta-cell volume in different planes in the body or left lobe. When quantifying beta-cell volume in health or disease, variation in the volume of beta-cells in different locations of the pancreas is an important consideration and the plane of transection may also influence results. 相似文献
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Lesions in the small intestine of newborn pigs inoculated with porcine, feline, and canine coronaviruses 总被引:4,自引:0,他引:4
The infectivity and pathogenicity to newborn pigs of antigenically related coronaviruses from pigs (transmissible gastroenteritis virus; TGEV), cats (feline infectious peritonitis virus; FIPV), and dogs (canine gastroenteritis virus; CGEV) were studied by light, scanning electron, and immunofluorescence microscopy. Hysterectomy-derived, 12-hour-old pigs were orally given tissue culture or frozen preparations of 6 coronavirus strains (3 porcine, 2 feline, and 1 canine). The pigs were killed at regular intervals between 24 and 144 hours after exposure. Virulent TGEV and virulent FIPV produced necrosis of villous epithelium, resulting in villous atrophy in the jejunum and the ileum. Similar, but less extensive and severe lesions, were produced by the 4 other viruses. Coronaviral antigens were identified by immunofluorescence in villous epithelial cells of pigs that had been inoculated with virulent TGEV, attenuated TGEV, virulent FIPV, and tissue culture-adapted FIPV. In contrast, coronaviral antigens were not induced by the small plaque variant TGEV and virulent CGEV in the villous epithelium, but rather in cells of the lamina propria and crypt epithelium. 相似文献
10.
Surgery of the bovine small intestine 总被引:1,自引:0,他引:1
D F Smith 《Veterinary Clinics of North America: Food Animal Practice》1990,6(2):449-460
Cattle require surgery for small-intestinal problems less frequently than they do for abomasal, forestomach, or large-intestinal problems. Close attention to local vascular anatomy is critical to success when intestinal resection is required. Cows with signs of severe abdominal pain may make rapid recoveries following prompt surgical treatment. This article discusses relevant anatomy of the small intestine and the diagnosis and treatment of intussusception, volvulus, obstruction by incarceration or entrapment, and duodenal obstruction. 相似文献
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D. C. Dodd B.V.Sc. 《New Zealand veterinary journal》2013,61(6):109-112
Abstract Extract Hypocuprosis in Northland as discussed in Part 1 of this paper gives support to the contention that copper supplementation either by injection or from topdressing is beneficial in lowering the incidence of post-parturient haemoglobinuria (P.P.H.) (Martinovich and Woodhouse, 1971) and maintaining higher levels of haemoglobin. 相似文献
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Pirone A Ding BA Lenzi C Baglini A Giannessi E Romboli I 《Anatomia, histologia, embryologia》2011,40(3):163-168
The presence and distribution of glucose-dependent insulinotropic polypeptide or gastric inhibitory polypeptide (GIP), gastric-releasing peptide (GRP) and glucagon immunoreactivity were studied in the small intestine of the New Hampshire chicken using immunohistochemistry. This is the first report of the presence of GIP-immunoreactive (ir) cells in avian small intestine. GIP, GRP and glucagon immunoreactivity was localized in the epithelium of the villi and crypts of the duodenum, jejunum and ileum. In particular, both in the duodenum and in the jejunum immunoreactive endocrine cells to GIP, GRP and glucagon were observed. In the ileum, we noticed GIP-ir and glucagon-ir cells. GRP-ir was found in nerve fibres of all three segments of the small intestine. The distribution of these bioactive agents in the intestinal tract of the chicken suggests that GIP and glucagon may play a role in the enteropancreatic axis in which intestinal peptides modulate pancreas secretion. 相似文献
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David E Anderson 《Veterinary Clinics of North America: Food Animal Practice》2008,24(2):383-401, viii
Surgical disorders of the gastrointestinal tract of cattle occur occasionally, and veterinarians are challenged to determine an accurate diagnosis and treatment for these conditions. Although surgical diseases most commonly occur in the forestomachs (dislocated abomasum, reticuloperitonitis) and the colons (cecal dilatation), this article focuses on lesions in the small intestine (duodenum, jejunum, ileum). 相似文献
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A Cristofolini M Fiorimanti M Campos E Sanchis T Diaz E Moschetti C Merkis 《Reproduction in domestic animals》2018,53(1):217-225
The early development in mammals is characterized by the contribution of nutrients from the maternal tissues through the placenta, which is in apposition with foetal membranes and the endometrium, allowing the physiological interchange between the embryos/foetuses and the mother. The aim of this work was to study the number of placental blood vessels and their vascular area through morphometric analyses and the haemotrophic diffusion distance in porcine placental tissues from early gestations, intermediates gestations, advanced gestations and term gestations. For those purposes, morphometric measurements, blood vessel quantification, high‐resolution light microscopy and transmission electron microscopy were performed. The implementation of the high‐resolution light microscopy allowed studying the placental vascular and tissue histoarchitecture with higher definition and resolution than using a conventional light microscopy. We highlight the close location of the subepithelial capillaries to the maternal/foetal interface as pregnancy progresses. We found statistically significant evidence to state that the area of blood vessels is dependent on the gestation period. In advanced gestations, the presence of numerous small blood vessels and its near location to foetal/maternal interface agree with the great remodelling reported in our previous studies. In conclusion, in gilts, given the type of non‐invasive epithelial placentation, the new blood vessels generation and of haemotrophic diffusion distance reduction, determined in this report, assure the maternal/foetal haemotrophic exchange efficiency during gestation. 相似文献