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1.
The vascular system of the large intestine of 12 horses was examined by means of vascular corrosion casts, histology and transmission electron microscopy providing the following results. The Aa. et Vv. breves et longae leave the mesenteric vessels, respectively the subserously on the teniae lying cecal vessels to reach the tela subserosa at the mesenteric margin. The short vessels enter the deeper layers of the wall instantly, whereas the Aa. et Vv. longae move towards the submucosa by penetrating the muscular layers after a variable subserous course. The tela submucosa contains an arterial and a venous vascular plexus. In broader areas of the submucosa a three-dimensional vascular network can be found. This consists of a deep and a superficial vascular plexus, which are closely interconnected. The deep plexus is applied to the inner circular muscles, whereas the superficial plexus is adjacent to the muscularis mucosae. The (deep) arterial plexus receives its afflux from the Aa. breves et longae and supplies parts of the circular muscle layer with recurrent muscle branches. The vascularisation of the mucosa also originates from the submucosal (superficial) plexus. In the basal tunica mucosa, the ascending arteries form a transversal network from which arterioles branch into periglandular capillaries around each Lieberkühn crypt. Close to the lumen, a polygonal subepithelial capillary system is formed. The capillaries turn into postcapillary venules immediately below the epithelium of the mucosal surface. Veins move vertically through the submucosa to enter the submucosal plexus after few inflowing side branches. Branches of the subserous-submucosal connections form an intermuscular plexus between the circular and longitudinal muscular layer. This plexus supplies the capillaries of the tunica muscularis. The subepithelial capillaries are predominantly lined with a fenestrated endothelium, whereas the capillaries of the pericryptal mucosa mainly show a continuous endothelial lining. The latter contain multiple vesicles, which may fuse in order to form transcytoplasmic channels. Sphincter-like muscle bundles at the transition points from capillaries to venules may provide hemodynamic regulatory structures in the submucosa of the horse. Veins with circumferential cushions of smooth muscle fibres, so-called ‘throttle veins’, are also found.  相似文献   

2.
The circulatory system of the large intestine of 27 pigs was examined by means of corrosion anatomy (vascular casts), histology and electron microscopy. The results were as follows: The Aa. et Vv. breves et longae leave the mesenteric vessels and reach the wall of the intestine at the mesenteric margin. The short vessels enter the deeper layers of the wall, whereas the Aa. et Vv. longae, by taking a variable subserous course, reach the submucosa af ter penetrating the muscular layers. The tela submucosa contains an arterial and a venous vascular plexus. Where the submucosa is larger, there is a three-dimensional vascular network, a deep and superficial vascular plexus that are closely interconnected. The deep plexus is applied to the inner circular muscles, whereas the superficial plexus is adjacent to the muscularis mucosae. The deep arterial plexus receives its af flux from the Aa. breves et longae and provides part of the circular muscle layers with recurrent muscle branches. The vascularization of the mucosa is derived from the (superficial) submucosal plexus. The arteries that ascend the tunica mucosa ramify, in the form of a brush, into some arterioles. In the basal part of the mucosa, they turn into a periglandular capillary system, i.e. a network around each Lieberkühn crypt. Close to the lumen, a polygonal subepithelial capillary system is formed. Below the epithelium of the mucosal surf ace, the capillaries turn into postcapillary venules. These are running vertically through the submucosa, with few infiowing side branches, and finally enter the submucosal plexus. An intermuscular plexus is formed by anastomoses between the circular and the longitudinal muscular layers from the branches of the subserous-submucosal connections. This intermuscular plexus provides the capillaries for the tunica muscularis. The subepithelial capillaries are, above all, furnished with a so-called fenestrated endothelium, whereas the capillaries of the pericryptal mucosa mainly show a continuous endothelium. The latter contains multiple vesicles that can fuse to form transcytoplasmic channels. In the wall of the large intestine of the pig, there are no sure indications as to the existence of either arterio-venous anastomoses or haemodynamic regulatory structures.  相似文献   

3.
The Vascular Architecture of the Porcine Small Intestine   总被引:1,自引:1,他引:0       下载免费PDF全文
The vascular anatomy of the porcine small intestine was studied by injection of intestinal vessels with India Ink. Examination of transverse and longitudinal serial sections of the injected intestine facilitated a three-dimensional interpretation of the vascular pattern. An artery from the mesentery penetrated the tunica muscularis, supplied muscular branches and passed on to the submucosa where it formed an arterial rete. From the submucosal arteries, arterioles arose and followed a direct axial course to the tips of villi where they ramified into a subepithelial capillary plexus. Some of the capillaries, at the midpoint of the villus, fused into paraxial venules, which emptied into a “transverse venule” at the base of the villus. Other villus capillaries were continuous with those of the crypts. The pericryptal capillary plexus received a few arterial branches from the submucosal arteries. The transverse venule and the pericryptal capillary plexus emptied into large, segmentally dilated veins in the submucosa. The submucosal veins formed an extensive anastomosing network drained by large venous trunks which passed through the muscle layers to the mesentery.

The observations suggest possible relationships between the vascular pattern and intestinal fluid movement.

  相似文献   

4.
Microvascular circulation of the small intestine in horses.   总被引:1,自引:0,他引:1  
The microvascular anatomic features of the small intestine was described by correlating results of microangiography, light microscopy, gross studies, and scanning electron microscopy of vascular replicas in 14 horses. After heparinization, the horses were euthanatized, a length of jejunum was transected, and blood was flushed free of the circulation, using isotonic NaCl solution. In six horses, the circulatory system was perfused with a modified radiopaque medium and evaluated radiographically. These sections were then evaluated by standard histologic methods. Sections from 8 horses were perfused with 1 of 2 types of plastics and studied grossly or by scanning electron microscopy. The marginal arterial arcade gives rise to vessels that enter the jejunum at the mesenteric angle. These vessels penetrated either directly, by branching and entering on both sides of the mesenteric angle, or supplying only 1 side of the mesenteric angle. All these vessels continued in the submucosa branching extensively, forming a submucosal plexus. This submucosal plexus supplied the tunica muscularis, tunica serosa, and the mucosa. Vessels within the 2 muscle layers ran parallel to the muscle fibers and, consequently, perpendicular to each other. The arterial supply to the mucosa penetrated the muscularis mucosae and branched to supply 2 mucosal capillary networks. An eccentrically placed arteriole penetrated the base of the villus and spiralled to the tip where it "fountained" into a mesh-like capillary network, which descended peripherally in the villus to drain via 1 to 3, but most commonly 2 venules. Venules from adjacent villi united and drained via the submucosal veins.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

5.
The blood vascular system of the stomach wall in the cat The results of 19 vascular-injections of the stomach wall in the cat are given. The arterial supply to the parietal surface is derived principally from the left gastric artery, that of the visceral surface from the short gastric branches of the splenic artery. Thus the arterial distribution is similar to the venous drainage. The blood supply of the tunica serosa and the tunica muscularis in the fornix and body regions arises from a common subserosal and muscular plexus. In the pyloric canal the blood supply arises from separate subserosal and intermuscular plexus. The submucosal plexus consists of both arteries and veins: from this, mucosal arteries ascend to a subglandular plexus and thence arterioles supply the capillary plexus of the lamina propria. Venules return the blood through collecting veins to a basal venous plexus, thence through mucosal veins to the submucosal plexus.  相似文献   

6.
As in other studied species the exclusively on the epithelial side existing ‘fenestrated endothelium’ of the pericryptal and subepithelial capillaries is doubtless the most important structural mark of the large intestinal function, too. Moreover, the direction of the mucosal capillary blood flow informs, that at first the release of the essential substances for the glandular secretion will take place, before epithelial transports concerning the resorption occur. As for the hemodynamic regulatory structures in the wall of the blood-vessels there are obviously differences in their existence depending on the species, respectively they are completely absent such as in the ruminants. Finally, it should be mentioned, that arterio-venous anastomoses could not be detected.  相似文献   

7.
Microvascular circulation of the ascending colon in healthy horses was studied using microangiography, light microscopy, and scanning electron microscopy. The pelvic flexure with 30 cm of ventral and dorsal colon attached was removed from 14 adult horses immediately after horses were euthanatized. The lumen was flushed with warm water, and this section of the ascending colon was placed in a 37-C bath of isotonic NaCl. In sections from 8 horses, colic vessels were perfused with a radio-opaque medium for microangiography. After angiographic evaluation, tissue sections were prepared for light microscopic observation, using standard histologic methods. In sections from 6 horses, injection replicas were made by perfusing the vessels with 2 types of plastics. The results of microangiography, light microscopy, and scanning electron microscopy of vascular replicas were correlated, providing a comprehensive documentation of the microvasculature of the ascending colon at the pelvic flexure. Arteries branched from mesenteric colic vessels approximately every 2 cm toward the colonic tissue. Immediately after branching, arterial vessels formed an anastomotic plexus, the colonic rete. However, each branch from the colic vessel eventually continued into the colonic tissue. A second set of vessels originated from the colonic tissue. A second set of vessels originated from the colonic rete and supplied the mesenteric lymph nodes. Arterial vessels penetrated the tunica muscularis into the submucosa 3 to 4 cm toward the antimesenteric border forming a submucosal vascular network. From the submucosal arterioles, branching took place at right angles to supply the mucosal capillaries. Capillaries surrounded the colonic glands and anastomosed at the luminal surface, forming a superficial luminal honeycomb-appearing vascular plexus.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

8.
The microvascular circulation of the cecum was studied in 15 adult horses, using microangiography and light microscopy combined with gross studies and scanning electron microscopy of vascular replicas. After heparinization, the horses were euthanatized and the cecum was transected at the cecocolic junction. Blood was flushed free of the circulation with isotonic NaCl and the cecal lumen was slightly distended. In 6 horses, the vascular system was injected with a modified radiopaque medium and evaluated radiographically. Sections evaluated radiographically were also prepared for histologic examination by standard methods. Eight horses were injected with 1 of 2 types of plastics and studied grossly or by scanning electron microscopy. In 1 additional horse, the lateral and medial arteries were injected with different colored plastic for gross studies. The lateral and medial cecal arteries appear to supply the respective areas of the cecum with minimal mixing of the 2 circulations. The major vascular supply to the cecal apex appeared to be through the medial cecal artery. Both the lateral and medial cecal arteries gave rise to cecal retia, which formed a mesh-like network around the respective veins. Vessels from these retia supplied the cecal tissue and the cecal lymph nodes. The continuation of the retia was through long terminal arteries that coursed around the circumference in the submucosa, forming an extensive submucosal plexus. This plexus supplied both the mucosa, and the tunica muscularis and serosa. Vessels within the longitudinal and circular muscle layers of the muscularis externa ran parallel to the muscle fibers, and consequently, perpendicular to each other.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

9.
The distribution of the putative motor excitatory neurotransmitter, substance P, was studied immunocytochemically in the left dorsal colon of four normal control ponies and three ponies with amitraz-induced impaction colic. Substance P-like immunoreactivity in the control ponies was observed in nerve fibres in all layers of the bowel wall and in the nerve cell bodies of the enteric ganglia. The substance P-like immunoreactivity was clearly more intense in the cell bodies of submucosal ganglia than in those of the myenteric ganglia. The internodal nerve strands of the myenteric plexus were very rich in substance P-like immunoreactivity and within the ganglia they formed dense varicose networks around the neuronal cell bodies. Nerve bundles rich in substance P-like immunoreactivity diverged inward from the myenteric plexus to contribute an abundance of varicose immunoreactive fibres to the circular muscle of the tunica muscularis. Nerve fascicles with substance P-like immunoreactivity were sparse in the longitudinal muscle except in the thickened taenial band. In the submucosa many of the nerve fibres with substance P-like immunoreactivity appeared to arise from ganglionic cell bodies. Immunoreactive fibres commonly condensed around arterial vessels in the submucosa. Fine immunoreactive nerve fascicles from the submucosal plexus also projected internally to supply the muscularis mucosae and form periglandular arrays in the lamina propria. The distribution of substance P-like immunoreactivity in the normal equine colon differed in some respects from patterns observed in large intestines of other mammals. When the colons of normal and amitraz-treated ponies were compared no differences were discerned in the distribution or intensity of substance P-like reactivity.  相似文献   

10.
The microvascular circulation of the descending colon was studied in 5 adult horses, using microangiography and light microscopy combined with gross studies and scanning electron microscopy of vascular replicas. After heparinization, horses were euthanatized, and 3 segments of the descending colon and its mesentery containing 1 vascular arcade were removed from each horse. The fecal balls were gently massaged from the lumen, and the blood was flushed free of the circulation with isotonic NaCl. In 5 segments, the vascular system was injected with a modified radiopaque medium and evaluated radiographically. Specimens examined radiographically also were prepared for histologic examination, using standard methods. Ten segments were injected with 1 of 2 types of plastics and studied grossly or by scanning electron microscopy. Arcuate arteries gave rise to a descending colonic rete that surrounded the vein and supplied numerous descending colonic lymph nodes. The rete also supplied the mesocolon and the descending colonic tissue. Short filamentous vessels arising from the rete directly penetrated the mesenteric tenia to supply an intermuscular plexus between the longitudinal and circular muscle layers of the muscularis externa. Larger vessels arising from either side of the rete divided into the long- and short-terminal arteries that supplied an extensive submucosal plexus, which was continuous around the circumference. The submucosal plexus supplied the mucosa, the tunica muscularis, and the serosa. Vessels running centrifugally from the submucosal plexus formed an intermuscular plexus between the longitudinal and circular muscle layers of the muscularis externa. The intermuscular plexus at the mesenteric angle also was supplied by vessels branching from the short-terminal arteries as they penetrated the muscularis externa.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

11.
The goat choroid plexus angioarchitecture of the lateral ventricles was studied under the SEM using the method of “microvascular corrosion casts”. The whole plexus is semilunar shaped and directed in an antero-posterior, latero-median fashion. In the plexus the lateral extremity is larger than the median one. All the components of the vascular bed (arteries, venes and capillaries) of the choroid plexus have interesting morpho-structural features. In particular, the capillaries are more developed than the other components and they are variously located on both sides of the plexus. The capillary network has a various organization in different zones of each side of the plexus.  相似文献   

12.
Microangioarchitecture of the mucosa of the Antrum pyloricum in rabbit was studied by optical and scanning electron microscopy. Passing the lamina muscularis mucosae, arteries of the submucosa reach the lamina propria and branch in to the terminal arteries forming a subglandular network. From these vessels, two capillary nets arise. The first forms a capillary skein around the base of the glands, while the second ascends along the tubuli, moving upwards to the surface along the glandular tubuli. These ascending capillaries also arise directly from the subglandular arterioles of the lamina propria, as well as from capillaries of the basal parts of the glandular tubuli. Subepithelial capillaries form arcuate loops with 2-3 venules or collecting venules, which run into the venous net in the basal region of the lamina propria. Numerous horizontal interconnections exist between the collecting venules but arteriovenous anastomosis in the mucosa was not observed.  相似文献   

13.
The blood supply to the equine pituitary gland, with special attention to its portal system, was studied by the aid of vascular injections and histological serial sections. The primary capillary plexus of the median eminence was supplied by the rostroventral and rostrodorsal infundibular arteries, which were branches of the internal carotid arteries and the ramus communicans caudalis, respectively. The neural lobe was supplied by the caudal infundibular arteries, which originated from the arteria intercarotica caudalis. Dorsal and ventral groups of the portal vessels were described. Their regional distribution into the sinusoidal capillaries of the pars distalis was discussed. Results of this investigation indicated that the portal vessels were the sole supply to the equine pars distalis. No direct arterial supply to this part of the adenohypophysis was observed.  相似文献   

14.
The development of the cecum and colon in the goose was investigated during the period from the 15th to 28th day of the incubation and from 1 to 30 days of age after hatching by light microscopy. By day 15 of the incubation, in the cecum and colon, the lumen was surrounded by pseudostratified epithelium. The previllous ridges appeared at 15th and 17th days of the incubation in the colon and ceca, respectively. At the base of previllous ridges, the epithelium changed into a simple prismathic epithelium at 15th and 17th days of the incubation in the colon and cecum, respectively. The villi appeared at the 21st days of the incubation. The crypts and goblet cells appeared on the first day after hatching. In the pre-hatching period, the lamina muscularis mucosa was present only in the colon. The submucosa consisted of loosely aggregated connective tissue in the pre-hatching period. In the post-hatching period, it consisted of a very thin layer of connective tissue. Its presence was only obvious where the cells of the submucosal nerve plexus or occasional large blood vessels considerably increased its thickness. The nerve plexus corresponding to the Auerbach's plexus of the mammalian intestine and submucosal nerve plexus appeared by 15th days of the incubation. From the 15th to 28th day of incubation, the tunica muscularis consisted of circular smooth muscle cells in the ceca. On the 28th day of the incubation a thinner longitudinal muscle layer added to the circular muscle layer. In the colon there was an outer longitudinal and a thicker circular muscle layer.  相似文献   

15.
Phocid seals exhibit vascular adaptations that allow them to undertake prolonged deep dives. These vascular adaptations are either unique to phocids, or are modified vascular equivalents to those present in terrestrial mammals. One such adaptation, the aortic bulb, is a spherical enlargement of the ascending aorta specific to phocid seals. Its histological make‐up consists of a reinforced tunica media with circular and longitudinal layers of elastic fibres. This reinforcement enables multi‐axial deformation of the aortic bulb, thus complementing its function as a prominent elastic reservoir or ‘windkessel’. A second adaptation, the hepatic sinus, is an asymmetrical dilation of the abdominal portion of the caudal vena cava and accompanying hepatic veins. The hepatic sinus is comprised of a relatively thin tunica media, with a scant smooth muscle component. The bulk of the sinus wall is comprised of tunica adventitia. A third vascular adaptation distinctive to the phocids is the pericardial venous plexus, composed of convoluted veins circumnavigating the perimeter of the heart. Microscopically, these veins have a thick tunica media and also contain valves. Smaller arteries, venules and distinct capillary beds are observed interspersed in‐between these veins. It can be hypothesized, that in seals, certain vascular embryonic development may be arrested at an earlier embryonic stage, resulting in these unusual vascular formations. These modifications play a vital role in blood pressure regulation and distribution of oxygenated blood during prolonged deep diving. The purpose of this work was to elucidate the histological aspects of these unique vascular modifications and relate them to specific function.  相似文献   

16.
本研究旨在探究胶质纤维酸性蛋白(glial fibrillary acidic protein,GFAP)在黄羽肉鸡肠道中的分布规律。使用免疫组织化学SABC-AP法,观察鸡肠道中GFAP的分布规律。结果显示,GFAP在鸡小肠黏膜上皮、小肠腺细胞腔面、小肠黏膜下神经丛和肌间神经丛及其血管壁周围均呈强阳性表达,在黏膜固有膜上呈阳性表达;GFAP在鸡大肠黏膜上皮、大肠腺中呈阳性表达,在大肠黏膜下神经丛和肌间神经丛均呈强阳性表达。GFAP是肠神经胶质细胞的特异性标记物之一,观察其在鸡肠道的分布特征有助于阐明肠神经胶质细胞在肠道各段的分布规律,为研究鸡肠神经胶质细胞的功能提供形态学依据。  相似文献   

17.
The experiment was conducted to explore the distribution of glial fibrillary acidic protein (GFAP) in Yellow feather broiler,and to investigate the morphological characteristics of glial cells of chicken. The distribution of GFAP was studied by immunohistochemistry SABC-AP method. The results showed that GFAP were expressed strong positively in chicken small intestinal mucosa epithelium, intestinal gland cell cavity surface, submucosal plexus and myenteric plexus; The expressions of GFAP were positive in the mucosal lamina propria and myenteric nerve plexus around the blood vessel; In avian escherichia sticky epithelial membrane, colorectal adenocarcinoma,GFAP were expressed positively, and the expressions were strong positive in mucosa epithelium, submucosal plexus and myenteric plexus. GFAP was one of the specific marker of enteric glial cells, and the observation of distribution of GFAP in chicken intestinal tract was help for elucidating the enteric glial cells in the distribution of the intestine and providing the morphological basis for the study of chicken glial cell function.  相似文献   

18.
The histomorphological changes occurring in the Dama dama reticulum during prenatal development have been investigated. Twenty‐five Dama dama embryos were used, from the first stages of prenatal life until birth. Differentiation of the reticulum was observed at 23% gestation. By 25% gestation the reticular wall comprised three layers: an internal epithelial layer, a middle layer of pluripotential blastemic tissue and an external layer or serosa. Primary reticular crests were visible at 38% gestation. Secondary reticular crests were observed at 61% gestation. Neuroendocrine cells were detected by synaptophysin (SYP) at 35% gestation, in the lamina propria‐submucosa, tunica muscularis, and serosa. Epithelial Cytokeratin‐18 (CK‐18) cells were observed at 35% gestation extended throughout the epithelial layers. The glial cells (vimentin –VIM‐ and glial fibrillary acidic protein‐GFAP‐markers) were discerned at 25% and 43% gestation, respectively, in myenteric and submucosal plexuses, lamina propria, muscularis mucosae, tunica muscularis, and perivascular connective tissue. The neuropeptide Y (NPY) and vasoactive intestinal polypeptide (VIP) markers were immunodetected at 75% and 80 gestation, respectively, in the lamina propria‐submucosa, muscularis mucosae, tunica muscularis, serosa, and myenteric plexuses. The prenatal development of the fallow deer reticular mucosa evidenced a considerable precocity similar to that previously reported in goat and red deer.  相似文献   

19.
Microvascular anatomy of the third compartment of the stomach of llamas   总被引:1,自引:0,他引:1  
OBJECTIVE: To characterize the vascular anatomy of the third compartment of the stomach of llamas. ANIMALS: 7 adult llamas. PROCEDURE: Immediately after each llama was euthanatized, vascular replicas of tissue from the third compartment were prepared by use of methylmethacrylate monomer and catalyst. Following chemical removal of tissue, the casts were further prepared for examination via scanning electron microscopy. By use of barium solution, microangiography was also performed on fixed tissue samples; the infused tissue was sectioned and imaged radiographically. Tissue samples were also collected for histologic evaluation after fixation and H&E staining. RESULTS: The third compartment was supplied by 4 pairs of primary arteries and veins located around the circumference of the structure. From these vessels, smaller arteries and veins branched to supply the serosal surface and penetrated deeper through the tunica muscularis to supply the submucosal and mucosal layers. An extensive capillary network was arranged in a hexagonal array surrounding the gastric glands, such that the mucosal aspect of the replicas had a honeycomb-like appearance. Histologically, variably sized villous projections lined by a single layer of epithelial cells with an extensive glandular network were observed. CONCLUSIONS AND CLINICAL RELEVANCE: The third compartment of the stomach of llamas is a highly vascular structure with an extensive anastomotic capillary network at the luminal surface. Branching vessels provide extensive collateral circulation, and it appears that surgical incisions should heal well. Incisions in the third compartment should be oriented parallel to the longitudinal plane.  相似文献   

20.
秦岭细鳞鲑消化系统的形态学观察   总被引:1,自引:0,他引:1  
运用大体解剖和常规组织学方法对秦岭细鳞鲑消化系统的组织形态进行了系统观察。结果表明,秦岭细鳞鲑的消化道由口咽腔、食道、胃和肠等4部分组成,除口咽腔外,管壁由内向外分为黏膜、黏膜下层、肌层和浆膜。口咽腔宽大,上颌、犁骨及腭骨等处布有细齿,黏膜衬以复层扁平上皮,间有较多的黏液细胞和少量的杯状细胞及味蕾;食管粗而短,黏膜向管腔突出形成多个纵行皱襞,上皮由复层扁平上皮逐渐向单层柱状过渡,上皮细胞间可见到数量较多的粘液细胞和杯状细胞,食管腺不发达;胃体积较大,呈“U”形,包括贲门部、胃体和幽门部,胃体部小凹及胃底腺结构明显,肌层发达;胃与肠相接处有63-65个幽门盲囊,肠道粗短而略微盘曲,黏膜上皮为单层柱状,未见明显的肠腺。以上结果显示,秦岭细鳞鲑消化道组织结构与其肉食性功能密切相关。肝小叶界限不清;双列肝细胞围绕中央静脉呈放射状走行,肝细胞个体大、呈多边形,核呈圆形或卵圆形,1-2个。胰脏大部分环绕前肠边缘、呈细长条索状,另可见分散于幽门盲囊及胃周围的弥散部分;其外分泌部为管泡状腺,腺细胞呈锥体形,胰岛结构明显。  相似文献   

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