Simulation of the economic impact of proliferative enteritis on pig production in Australia

The economic impact of proliferative enteritis (PE) on an ‘average’ pig farm was calculated using the AUSPIG decision support system. Inputs were modelled on actual cases of PE, in which affected herds suffered from depressed growth rate, decreased feed efficiency and stock losses. The costs associated with non-haemorrhagic PE and proliferative haemorrhagic enteropathy ranged from $15/sow/yr to $141/sow/yr, respectively, depending on the clinical severity of the disease, incidence of infection and the type of medication strategy used to treat and control the disease.     

Financial impact of transmissible gastroenteritis in pigs

The financial impact of an epizootic of transmissible gastroenteritis in pigs was evaluated in a California sow herd through estimating growth, feed, and profit functions. Two groups of pigs were studied: pigs born before and surviving the epizootic (epizootic [E] pigs), and pigs born after the epizootic (postepizootic [PE] pigs). Short-term profits were maximized at 165 days for both groups of pigs, ranging from $47.14 for female E pigs to $60.32 for male PE pigs. Accordingly, it was concluded that pigs surviving or born shortly after a transmissible gastroenteritis epizootic are profitable to raise, if raised under management conditions similar to those in the study herd.     

The economic impact of clinical transmissible gastroenteritis for swine producers participating in the Missouri mail-in-record program

Economic loss from transmissible gastroenteritis (TGE) was estimated at $0.18 per hog marketed for the average Missouri Mail-in-Record swine panel producer in 1978. This cost was $0.19 per hog marketed in 1979. These estimates were averaged for all producers in the record system, those with TGE in their herds as well as TGE-free herds. Estimates were also prepared for those herds with TGE outbreaks. In 1978, the average loss due to TGE for producers who had the disease on their farms was estimated at $1.74 per hog marketed, or 18% of the average return earned above total production costs. In 1979, this cost was $1.25 per hog marketed, or 13% of the average return earned above total production costs.     

猪传染性胃肠炎病毒的诊断研究进展

猪传染性胃肠炎（Swine transmissble gastroenteritis,TGE）是由猪传染性胃肠炎病毒（Swine transmissble gastroenteritis virus,TGEV）引起的主要以2周龄以内的仔猪发生呕吐、严重腹泻和脱水为特征的一种高度接触性病毒传染病。1933年,美国的依利诺斯州就有本病的报道,     

Concurrent porcine rotaviral and transmissible gastroenteritis viral infections in a three-day-old conventional pig.

A 3-day-old suckling pig with diarrhea was necropsied, and immunofluorescent microscopic examination of the small intestinal mucosa, together with immune electron microscopic examination of the large intestinal contents, provided a presumptive diagnosis of a concurrent infection with transmissible gastroenteritis (TGE) virus and porcine rotavirus. Immunofluorescent microscopic, immune electron microscopic, and serologic data obtained from gnotobiotic pigs experimentally inoculated with the large intestinal contents of the suckling pig confirmed this diagnosis. Two gnotobiotic pigs, convalescent from previous TGE viral infections, became infected with porcine rotavirus only. However, another gnotobiotic pig, convalescent from a previous porcine rotaviral infection, became infected with TGE virus only, following inoculation with the large intestinal contents of the suckling pig.     

猪传染性胃肠炎疫苗的研究进展

猪传染性胃肠炎是由猪传染性胃肠炎病毒(TGEV)引起的一种以严重腹泻、呕吐和脱水为临床特征的高度接触性传染病。可侵害各年龄的猪,已成为猪的一种世界性疾病,给养猪业造成巨大经济损失,有效的疫苗接种是目前大多数国家控制本病流行的重要措施。在过去的十年中,人们重点构建基因工程疫苗,但效果不一。灭活苗或弱毒活苗虽然仍显示着良好的优势,但一种安全、有效新型疫苗的研制已成为必然趋势。     

猪传染性胃肠炎病毒(TGEV)研究进展

猪传染性胃肠炎 (TGE)是由猪传染性胃肠炎病毒 (TGEV)引起的一种以严重腹泻、呕吐和脱水为临床特征的高度接触性传染病。 TGE首次由Doyle和 Hutchings1 946年在美国报道 ,日本 (1 95 6年 )和英国 (1 95 7年 )先后报道该病 ,这之后欧洲、北美、亚洲等多个国家相继报道发生了 TGE,现已成为一种世界性猪的疾病。我国从 6 0年代起就有TGE的报道 ,近些年来有进一步流行的趋势 ,尤其是冬季和早春寒冷季节常呈地方性暴发流行 ,给养猪业造成极大危害。在 1 984年和 1 986年间 ,欧洲北美等地又报道了一种特别的 TGEV自然缺失变异株 -猪呼吸…     

Molecular biology of transmissible gastroenteritis virus

The causative agent (TGEV) of porcine transmissible gastroenteritis belongs to the Coronaviridae, a family of enveloped viruses with a positive, single-stranded RNA genome. Important progress has recently been made concerning the molecular biology of TGEV. The research work of our group has been focused on two main aspects: genome structure and functional domains of the envelope proteins. TGEV genomic RNA is organised into seven regions. The sequence of six of them, i.e. the 3' most 8300 nucleotides, has been established from cDNA clones. Three genes encoding the structural proteins, the peplomer protein E2, the transmembrane protein E1 and the nucleoprotein, have been identified. Additional open reading frames allowed for the prediction of four non-structural polypeptides, the role of which remains to be discovered. The remaining part of the genome (estimated length 20 kb) is thought to encode the polymerase. Expression of TGEV genes involves the production of six subgenomic mRNAs, which together with the virion RNA, form a 3' terminal nested set. The peplomer glycoprotein E2 (220 kDa) is 1431 residues long and highly glycosylated. Several domains were identified, including a C-terminal anchoring region and at least four major antigenic sites, which cluster in the amino half part of the molecule. Two sites containing most of the critical neutralisation determinants are highly conserved among TGEV strains. The glycoprotein E1 (29kDa) is mostly embedded in the membrane and plays a crucial role in the virion architecture. However, a short N-terminal domain protruding out of the particle mediates complement-dependent neutralisation, and induces alpha interferon synthesis, likely through a direct interaction with the lymphocyte membrane.     

仔猪传染性胃肠炎的防治

仔猪传染性胃肠炎是由猪传染性胃肠炎病毒引起的一种急性、高度接触性传染病。主要是经过消化道和呼吸道感染,以水样腹泻、呕吐、脱水、仔猪迅速死亡为特征。今年春季在本镇各村均有发生,有48％的饲养户的仔猪不同程度发病。     

中药制剂“清增康”对猪冬痢的疗效试验

材料与方法,1.1试验药物,"清增康"散剂由白头翁、黄柏、连翘、秦皮、茯苓、地榆、石榴皮共13味中味药组成,置于65C烘箱内烘干,粉碎为细末,过40目筛.     

Methanol precipitation of transmissible gastroenteritis virus.

Methanol precipitation of transmissible gastroenteritis virus was tested at Ph 4.0, 5.0, 6.0, and 7.0 and at methanol concentrations of 15%, 25%, and 30%. Supernatant and precipitate fractions were tested for complement-fixing and agar-diffusion soluble antigens and plaque-forming units, and were examined by electron microscopy. Virus could be obtained free of detectable agar-diffusion antigens and most of the complement-fixing antigens. Most of the virions were without peplomers after methanol treatment but they retained infectivity.