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微生态制剂是对动物机体有益的菌类,它能提高动物机体的免疫功能,促进生长,改善动物产品的质量,能有效替代抗生素的促生长和预防保健作用。由于微生态制剂能克服抗生素所产生的副作用,使用安全、无污染的绿色食品添加剂,其社会效益和经济效益是显著的。 相似文献
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机体免疫力的高低直接决定机体的抗病力和生产力,中草药在免疫促进方面显示了独特的优越性。玉屏风散在免疫药理学方面有广泛的影响。文章就玉屏风散对动物免疫功能的影响及其在临床方面的应用进行了综述。 相似文献
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微量元素直接影响动物免疫器官的发育,影响动物的特异性和非特异性免疫功能,而且对于机体内微生物的生长、繁殖、代谢及毒素的产生也具有十分重要的调控作用。本文对主要的微量元素对动物免疫功能的影响作一概述。 相似文献
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益生菌在动物生产中的应用与发展趋势 总被引:1,自引:0,他引:1
益生菌能优势定植于消化道.一方面通过其自身的代谢产物来抑制病原菌,增强机体免疫力;另一方面,有益菌能分必一些特异性抑菌物质,直接抑制外源性和内源性有害菌的生长繁殖.同时,益生菌能提高饲料转化率,促进动物生长.益生菌对动物机体的影响主要对体现在动物免疫力上,它非特异性地激发机体的细胞免疫和体液免疫而产生抗体,因而益生菌在畜禽生产中应用广泛. 相似文献
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复方生茸散的生茸机理与生茸效果的实验研究 总被引:3,自引:0,他引:3
复方生茸散是以中药为主组成的复方药物添加剂,该制剂具有促进食欲,增强造血功能,促进骨髓DNA和RNA的合成,改善末梢血液循环,增加末梢血液供给,调节局部代谢,改善营养,提高机体免疫功能的作用。应用于梅花鹿的生茸期,按30g/d的剂量将复方生茸散混于精料中喂给,每天1次,连用60-75d,平均每头鹿多增鲜茸309-560g,增茸效果显著。 相似文献
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The immune response genes of the mouse encode two cell-surface glycoproteins, I-A and I-E, that play critical roles in determining the animal's immune responsiveness. The I-A antigen contains two chains, alpha and beta. A cloned beta-chain gene, I-A beta k, was introduced into B-lymphoma cells that express I-Ad. The transfected gene was successfully expressed on the cell surface of the recipient cells and was functional in stimulating allospecific T cells. 相似文献
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Immunologic tolerance: collaboration between antigen and lymphokines 总被引:15,自引:0,他引:15
G J Nossal 《Science (New York, N.Y.)》1989,245(4914):147-153
Immunologic tolerance is the process whereby limits are placed on the degree to which lymphocytes respond to an animal's inherent antigens. It is a quantitative rather than an absolute term, as some autoantibody formation is common. Contrary to early hopes, it is not due to some single, simple causative mechanism confined to early developmental stages of the fetal immune system. Rather, self-tolerance results from a variety of complementary mechanisms and feedback loops in the immune system and is thus best seen as part of the general process of immunoregulation. 相似文献
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维生素C是水生动物必需的营养物质,在促进生长、抵抗疾病、增强机体免疫力等方面发挥着十分重要的作用。本文综述了水生动物对维生素C的合成能力、缺乏症、必要性、需要量及需要量的评定标识等方面的研究进展。 相似文献
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动物疫病是畜牧业生产的大敌,要发展畜牧业生产就要防治动物疫病。但在疫苗接种时,经常出现正常反应外的其他不利于机体的反应,如废食、皮疹、休克、死亡等,正确处理或避开这些问题,对推行动物疫病的计划免疫,实施强制免疫,保护人畜安全具有十分重要的现实意义和作用。 相似文献
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Toll-like receptors (TLRs) control activation of adaptive immune responses by antigen-presenting cells (APCs). However, initiation of adaptive immune responses is also controlled by regulatory T cells (TR cells), which act to prevent activation of autoreactive T cells. Here we describe a second mechanism of immune induction by TLRs, which is independent of effects on costimulation. Microbial induction of the Toll pathway blocked the suppressive effect of CD4+CD25+ TR cells, allowing activation of pathogen-specific adaptive immune responses. This block of suppressor activity was dependent in part on interleukin-6, which was induced by TLRs upon recognition of microbial products. 相似文献
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Salmon D Vanwalleghem G Morias Y Denoeud J Krumbholz C Lhommé F Bachmaier S Kador M Gossmann J Dias FB De Muylder G Uzureau P Magez S Moser M De Baetselier P Van Den Abbeele J Beschin A Boshart M Pays E 《Science (New York, N.Y.)》2012,337(6093):463-466
The parasite Trypanosoma brucei possesses a large family of transmembrane receptor-like adenylate cyclases. Activation of these enzymes requires the dimerization of the catalytic domain and typically occurs under stress. Using a dominant-negative strategy, we found that reducing adenylate cyclase activity by about 50% allowed trypanosome growth but reduced the parasite's ability to control the early innate immune defense of the host. Specifically, activation of trypanosome adenylate cyclase resulting from parasite phagocytosis by liver myeloid cells inhibited the synthesis of the trypanosome-controlling cytokine tumor necrosis factor-α through activation of protein kinase A in these cells. Thus, adenylate cyclase activity of lyzed trypanosomes favors early host colonization by live parasites. The role of adenylate cyclases at the host-parasite interface could explain the expansion and polymorphism of this gene family. 相似文献
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酚氧化酶(Phenoloxidse,PO)是昆虫体内一类重要的氧化酶,在昆虫的正常生长发育过程中具有重要的生理功能。阐述酚氧化酶在昆虫免疫防御及其他生理发育过程中的作用机制,以及可能影响昆虫发育和免疫的诸多因子与酚氧化酶间的关系,以期为进一步探究酚氧化酶对昆虫自身调控机制提供新的思路。 相似文献