应用丙硫苯咪唑驱除绵羊体内寄生虫的增重试验报告

为了观察丙硫苯咪唑对绵羊体内寄生虫的驱除效果，肯定驱除体内寄生虫对绵羊的增重作用，为增加养羊业的生产效益提供参考依据。试验选择80只青年绵羊，分为两个不同的组别，试验组投服丙硫苯咪唑片剂，对照组不投药，然后进行定期的虫卵实验室监测和分期的活体称重，最后进行试验数据统计。试验结果表明：（1）丙硫苯咪唑的驱虫作用广谱、安全，对绵羊体内多种寄生虫的驱除效果确实。按20mg／kg体重剂量投服，其药物残效期大约能维持30d左右。（2）4g内驱虫对绵羊增重作用明显，经济效益可观。试验组6个月内比对照组多增重41kg，投资回报率为1：20，即花1元钱驱虫药费，可增加20元净收入。     

丙硫苯咪唑驱除绵羊胃肠道线虫的试验

丙硫苯咪唑驱除绵羊胃肠道线虫的试验宗泽群汪作民石剑华斯钦昭日格１昭日格图２内蒙古赤峰市畜牧兽医科学研究所赤峰０２４０３１；１巴林右旗幸福之路苏木兽医站；２巴林右旗巴彦他拉苏木兽医站据调查，赤峰地区六月龄以上的放牧绵羊胃肠道线虫感染率达１００％，强度在...     

丙硫苯咪唑瘤胃控释剂绵羊春季驱虫试验

绵羊１５０只，分三组进行春季驱虫试验，试验组羊投放丙硫苯咪唑瘤胃控释剂１牧／只，阳性药物对照组羊一次口服丙硫苯咪唑１０ｍｇ／ｋｇ体重，空白对照组不给任何驱虫药物，分别于投药前和投药后１５、３０、４５、６６、８６、１２０和１４０天进行粪便虫卵计数，称取体重和剪毛。结果表明，试验组在给药后８６天时，虫卵减少率为９３．７％，驱净率为８８％；阳性药物对照组在给药后４５天时，虫卵减少率已降至７７．４％，驱净     

左旋咪唑和丙硫苯咪唑对绵羊寄生虫的驱虫结果及分析

左旋咪唑和丙硫苯咪唑是广谱、高效、低毒的驱虫新药，根据报导对各种畜禽的寄生虫有很好的驱虫效果，我们为了掌握这两种驱虫新药在本地对绵羊寄生虫的驱虫效果和最佳的驱虫剂量，对今后这两种药的推广应用提供科学依据，故进行本试验。     

丙硫苯咪唑控释剂对绵羊的驱虫试验

将丙硫苯咪唑控释剂给羊投服 ,于给药前及给药后 30d、60d、90d、12 0d进行粪便虫卵计数并逐一称取体重。结果表明 ,丙硫苯咪唑控释剂组投药 90d后虫卵减少率为 88 2 % ,能较长时间防止寄生虫感染 ,与丙硫苯咪唑对照组、空白对照组比较有明显的增重效果 (P <0 0 1)。     

丙硫苯咪唑瘤胃控释剂对绵羊秋秀驱虫的试验

绵羊３６０只，分三组。试验组投放丙硫苯咪唑瘤胃控释剂１枚／只，阳性药物对照组一次口服丙硫苯咪唑１０ｍｇ／ｋｇ体重，空白对照组不给任何驱虫剂，分别于投药前及药后７、３０、１００和１７０天进行虫卵计数，称取体重和毛量。结果表明，投药后７和３０天，试验组与阳性药物对照组均有良好的驱虫效果。投药后１００天，试验组驱净率为８５．５％，阳性药物对照组驱净率为２６．４％。给药后１７０天，试验组、阳性药物对照组与     

丙硫Ben咪唑对藏系绵羊寄生虫驱虫效果试验

驱虫是畜防工作的一项中心任务，是畜牧业生产发展非常重要的关键环节。1990年开始在我州全面推广驱虫这一“畜防工程”，牲畜寄生虫的感染强度和感染率明显下降，对降低春乏死亡，提高牲畜抗病能力，效果十分显著。     

丙硫苯咪唑驱除绵羊肝脏双腔吸虫幼虫的试验

丙硫苯咪唑驱除绵羊肝脏双腔吸虫幼虫的试验张俊安（山东省垦利县永安乡兽医站）宋立业，谭学堂（山东省垦利县畜牧兽医站）王玉茂，胡汉亭（山东省滨州地区畜牧兽医研究所）寄生于牛羊肝脏的双腔吸虫病，是危害本区绵羊的严重疾病之一。经多年调查，绵羊双腔吸虫的感染率...     

阿维菌素和丙硫苯咪唑对巨晰体内寄生虫的驱除试验

用丙硫苯咪唑和阿维菌素对国家一级保护野生动物巨蜥进行驱进行驱虫试验，每种药物设2个剂量组，每组6个重复。口服丙硫苯咪唑40.0mg/kg剂量组的胃肠道线虫虫卵减少率和虫卵转阴率分别为91.49%和83.33%，20.0mg/kg的剂量无效。皮下注射阿维菌素0.3mg/kg和0.6mg/kg剂量组的胃肠道线虫虫卵减少率和虫卵阴率均达100%。试验结果表明，用丙硫苯咪唑驱除巨蜥消化道线虫需较高剂量，较小剂量的阿维菌素对驱除巨蜥消化道线虫效果很好。     

丙硫苯咪唑瘤胃控释剂对绵羊驱虫效果试验

丙硫苯咪唑瘤胃控释剂投喂羊只后３０ｄ时，虫卵减少率和虫卵驱净率试验组为９９．７８％和９０％，阳性药物对照组为９９．６２％和８５．７１％；６８ｄ时，试验组呈上升趋向，为９９．８３％和９２．３％，阳性药物对照组为９７．３１％和５７．１４％，已出现下降势态；１０４ｄ时，试验组为９９．３３％和７６．９２％，阳性药物对照组为９４．２６％和３７．５％，差异极显著（Ｐ＜０．０１）。     

荷斯坦育肥牛饮喂甲醛液的增重效果试验

选用西宁市奶牛场荷斯坦育肥牛 1 6头 ,随机分为试验组和对照组 ,每组为 8头。试验组饮喂 1 50 ppm甲醛液 ,对照组饮自来水。试验期 50天。结果表明 ,试验组和对照组平均增重分别为 51 .0 0千克和 2 8.50千克 ,日增重分别为 1 0 2 0克和 570克 ,差异极显著 (p<0 .0 1 )。     

Uptake of albendazole and albendazole sulphoxide by Haemonchus contortus and Fasciola hepatica in sheep

The pattern of in vivo uptake of albendazole (ABZ) and its major metabolite, ABZ-sulphoxide (ABZSO), by Haemonchus contortus and Fasciola hepatica recovered from ABZ-treated sheep, was investigated. Concentration profiles of both compounds were simultaneously measured in target tissues/fluids from the same infected sheep. In addition, the proportion of the (+) and (-) ABZSO enantiomers was determined in plasma, bile and F. hepatica recovered from treated sheep. Sheep naturally infected with H. contortus were intraruminally (i.r.) treated with ABZ (micronized suspension, 7. 5mg/kg) and the plasma concentrations of ABZSO and ABZ-sulphone (ABZSO(2)) determined in addition to the concentration of ABZ and ABZSO in H. contortus, abomasal mucosa and fluid content samples. In addition, F. hepatica artificially infected sheep were treated i.r. with the same ABZ suspension (7.5mg/kg), and samples of blood, bile, liver tissue and adult flukes were collected and analysed by HPLC to determine the concentrations of ABZ and both enantiomers of ABZSO. ABZSO and ABZSO(2) were the analytes recovered in plasma with ABZ and ABZSO present in H. contortus. ABZ was the analyte recovered at the highest concentration in H. contortus and abomasal mucosa, whereas higher concentrations of ABZSO were measured in abomasal fluid content. Only low concentrations of ABZ were detected in F. hepatica and bile, but markedly higher concentrations of ABZ were measured in liver tissue. ABZSO was the main molecule recovered in F. hepatica, plasma and bile samples collected from ABZ-treated sheep. The (+) enantiomer of ABZSO was recovered at a higher proportion in plasma (75%), bile (78%) and F. hepatica (74%) after ABZ administration to infected sheep.     

牛羊药物驱虫的增重对比试验

为证实牛羊药物驱虫后的增重效果。进行了本试验，各选粪检寄生虫卵阳性的牛羊100头，试验组与对组各羊。采用广播，高效的丙硫咪唑和阿福丁为试验组牛羊驱虫，丙硫咪唑牛用剂量20mg/kg，羊15mg/kg。阿，福剂量牛羊均用5mg/kg，试验期90天，第1次驱虫，15天后重复1交,于驱虫后45天和90天各称重1次，结构果表明，驱虫后牛膘情明显上升，至试验结束，试验组牛平均增重23．73kg/头，对照组（未用药）为13．25kg/头；羊分别为7．19kg/只，3．14kg／只。结论：牛羊驱虫后体增重明显，提高了经济效益。     

蛋氨酸铜对绵羊增重及体内代谢的影响

26只晋中绵羊随机分为试验组(添加蛋氨酸铜)和对照组(添加硫酸铜),供试日粮及营养水平完全相同,试验时间60d。结果表明,试验组比对照组绵羊平均日增重提高34.22%(P<0.05);平均日粮干物质采食量、肝脏铜和血浆铜含量明显提高(P<0.05)。     

The disposition of albendazole in sheep

Albendazole (ABZ) was administered intraruminally at 4.75 mg/kg to sheep fitted with a permanent bile-duct cannula to determine if its metabolites might contribute to its flukicidal action. ABZ metabolism was consistent with first-pass clearance by the liver, resulting in ABZ sulphoxide (ABZ-SO) and ABZ sulphone (ABZ-SO2) being present in plasma at maximum concentrations (mean Cmax +/- SD) of 2.0 +/- 0.2 micrograms/ml and 0.4 +/- 0.1 micrograms/ml after 8 +/- 3 h and 24 +/- 5 h, respectively. ABZ-SO, but more particularly ABZ-SO2, appeared to bind to plasma proteins but their clearance rates from plasma were similar. Biliary ABZ metabolites were mainly unconjugated ABZ-SO and 2OH-ABZ-SO (8.0% dose) or conjugated glucuronide and sulphate esters (6.3% dose) mainly of 2OH-ABZ-SO and 2OH-ABZ-SO2. The concentration of the major biliary metabolite, unconjugated ABZ-SO, followed a similar time profile to that of ABZ-SO in plasma except that Cmax was much higher (6.2 +/- 2.2 micrograms/ml). Intraruminal administration of ABZ reduced bile flow rate by 30% which may be attributable to an inhibitory effect of ABZ on microtubule formation in hepatic secretory cells. It is suggested that ABZ is sequestered in the liver. This is unlikely to contribute to its flukicidal action, which is probably attributable to ingestion of ABZ-SO from bile and blood by the fluke.     

蛋氨酸络合盐对小尾寒羊的增重效果

20只2月龄小尾寒羊随机分为试验组（添加蛋氨酸络合盐）和对照组（添加微量元素硫酸盐），供试日粮及营养水平完全相同，正试期120天。结果表明：试验组比对照组日增重提高15．85％，差异显著（P＜0．05）。     

日粮中添加不同剂量葡萄渣对成年羊增重效果的影响

选择28只健康无病、体重相近(P>0.05)的小尾寒羊成年母羊,分为试验Ⅰ组(对照组)、Ⅱ组、Ⅲ组和试验Ⅳ组,在相同的饲养管理条件下进行饲养试验,研究在日粮中添加不同剂量(8%、16%、24%)的葡萄渣对成年羊体增重的影响。结果表明:在日粮中添加不同剂量的葡萄渣对成年羊的体增重、平均日增重、饲料转化效率等均有显著影响(P<0.05)。     

不同处理方式的秸秆对舍饲肉羊育肥增重的影响

文章旨在评估不同处理方式的秸秆对舍饲肉羊育肥增重的影响,采用秸秆综合处理技术,对肉羊进行了120?d的饲养试验.结果表明,与放牧组相比,2、3、4组平均末重增加6.48、8.45、10.75?kg,分别增加23.64％、30.84％、39.23％;在只均增重方面分别增加20.36％、31.57％、38.13％;在平均日...     

沙葱、地椒和大蒜素对绵羊体增重效果的影响

试验选用 5月龄、体重相近的细毛羊×本地羊杂交后代育成羊 30只 ,随机分成 10组 ,1组为对照组、其余 9个试验组分 3个大组 ,分别饲喂 3个水平的沙葱、地椒冻干粉和大蒜素。试验结果证明 ,2 5 %大蒜素的最佳饲喂水平为 1.3～ 1.5g/ (只·d) ,地椒的最佳饲喂水平为 14～18g/ (只·d) ,沙葱的最佳饲喂水平为 15～ 17.5g/ (只·d) (按干物质计算 )。