饲料中喹乙醇检测条件研究

喹乙醇又称喹酰胺醇,商品名为快育灵或倍育诺,是20世纪70年代初研究合成的一种饲料添加剂,因其具有良好的广谱抗菌效果,尤其对大肠杆菌和沙门菌等革兰阴性致病菌所致的消化道疾病具有良好的疗效,并且有提高畜禽饲料消化率及生长速率等作用,被广泛用于兽药及饲料添加剂中.相对其他兽药,喹乙醇添加成本较低,大部分饲料厂特别是中小饲料厂多用其作为畜禽配合饲料的药物添加剂.若长期过量添加会导致蓄积性中毒及残留于畜产品中,对人体有较大危害.     

饮料中喹乙醇检测条件研究

喹乙醇又称喹酰胺醇,商品名为快育灵或倍育诺,是20世纪70年代初研究合成的一种饲料添加剂,因其具有良好的广谱抗菌效果,尤其对大肠杆菌和沙门菌等革兰阴性致病菌所致的消化道疾病具有良好的疗效,并且有提高畜禽饲料消化率及生长速率等作用,被广泛用于兽药及饲料添加剂中。相对其他兽药,     

家禽喹乙醇中毒临诊特征及原因探讨

喹乙醇(olaquindox)又名倍育诺、快育灵,因其具有良好的广谱抗菌效果,尤其是对大肠杆菌、沙门氏杆菌等革兰氏阴性致病菌所致的消化道疾病具有良好的疗效,并具有促进畜禽对饲料的消化利用、提高生长速度等作用而被广泛用于多种兽药及饲料添加剂中,在正确使用的前提下确能产生良好的效果,对生产起到一定的促进作用,尤其在饲养环境较恶劣的场地使用效果更为显著。然而,由于存在使用方法不当等问题,在生产实践中家禽喹乙醇中毒的案例时     

使用喹乙醇应注意的问题

喹乙醇又称喹酰胺醇、快育灵、倍育诺等,是近年来在我国被广泛推广应用的饲料添加剂.它具有较强的广谱抗菌作用(对革兰氏阳性菌、阴性菌均具有较强的抑制作用)和明显促进蛋白质合成作用,是用于预防、治疗畜禽疾病和促进畜禽生长较理想的饲料添加剂.喹乙醇毒性很小,但在实际应用中却时有发生畜禽喹乙醇中毒的报道.中毒原因多为使用不当造成的.使用喹乙醇应用注意以下几点:     

养鸡慎用喹乙醇添加剂

喹乙醇作为畜禽饲料添加剂,得到广泛使用,在促进畜禽生长方面起到良好作用,在畜禽疾病防治中也有一定作用.喹乙醇又称喹酰胺醇,商品名为倍育诺、快育灵,是一种新型化学药物添加剂.     

夏季鱼塘施药“四要五忌”

喹乙醇作为畜禽饲料添加剂,得到广泛使用,在促进畜禽生长方面起到良好作用,在畜禽疾病防治中也有一定作用。喹乙醇又称喹酰胺醇,商品名为倍育诺、快育灵,是一种新型化学药物添加剂。     

一例羊喹乙醇中毒的诊治

<正>喹乙醇(Olaquindox)属喹哑琳类药物,又名喹酰胺醇、快育灵、倍育诺等,外观呈淡黄色结晶粉末,微溶于热水、难溶于冷水、不溶于一般有机溶剂。1965年由西德拜尔(Bayer)公司首先合成的饲料添加剂,具有抑菌与蛋白同化作用,是促生长的药物,具有改善饲料转化率、提高畜禽生长率的作用,并有用量少、价格便宜、使用方便、不易产生耐药性及防治畜禽霍乱等病的优点,是一种理想的饲料添加剂。我国于20世纪80年代初开始应用于畜牧业生产,《中华人民共和国兽药典》(1990版)已有收载,主要作为畜禽的预混剂应用。但喹乙醇具有     

喹乙醇及其在畜禽养殖中的应用

喹乙醇(Olaquindox)又称喹酰胺醇,商品名为快育灵、倍育诺(Bayanox),是70年代初由西德拜尔药厂研究合成的饲料添加剂。其具有良好的广谱抗菌效果,尤其是对大肠杆菌、沙门氏杆菌等革兰氏阴性致病菌所致的消化道疾病具有良好的疗效,并能促进畜禽对饲料的消化利用,提高生长速度等,因而被广泛用于多种兽药及饲料添加剂中。在正确使用的前提下,确实产生了良好的效果,对生产起到了一定的促进作用,尤其在饲养环境较恶劣的场地使用效果更为显著。我国于1981年由北京营养源研究所研制成功,并已广泛用作畜禽生长促进剂。然而,由于存在使用…     

喹乙醇的特性及其规范合理使用

喹乙醇(Olaquindox)又称喹酰胺醇、喹奥多斯、倍育诺,商品名有快育灵、灭霍灵、灭败灵等,是1965年德国拜耳(Bayer)公司以邻硝基苯胺为原料合成的饲料药物添加剂,我国于1981年由北京营养源研究所研制成功。因其具有良好的广谱抗菌作用、尤其是对大肠杆菌、沙门氏杆菌、巴氏杆菌等所     

喹乙醇的特性及其合理使用

喹乙醇,又称喹酰胺醇、喹奥多斯、倍育诺,商品名有快育灵、灭霍灵、灭败灵等,是1965年德国拜耳(Bayer)公司以邻硝基苯胺为原料合成的饲料药物添加剂,我国于1981年由北京营养源研究所研制成功。因其具有良好广谱抗菌作用,尤其是对大肠杆菌、沙门氏杆菌、巴     

商会自治的基石——商会自治规范研究

在现代法律秩序中,商会自治规范是制定法的基础和必要的补充,甚至在某些方面替代了制定法;商会自治规范主要包括商会组织规范、行为规范、惩罚规范以及争端解决规范等;其效力仅及于其内部成员;商会自治规范和制定法之间存在冲突,但也存在整合的基础。     

癸氧喹酯干混悬剂含量测定的改进

采用高效液相色谱法测定癸氧喹酯干混悬剂的含量,在2-250μg/mL范围内,峰面积的常用对数与进样量浓度的常用对数呈良好的线性关系,R^2=1(n=5),平均回收率为99.24%~99.51%,RSD在0.05%~0.28%。此方法分析时间短,样品前处理简便、定量结果准确,重现性好,结果满意,为其质量控制提供了依据。     

猪毛色遗传的研究进展

本文概述了猪的毛色类型、猪的毛色遗传模式,着重综述了猪毛色基因分子基础的研究进展,指出存在问题并就未来发展方向做了思考。     

Comparison of 2 methods of centesis of the bursa of the biceps brachii tendon of horses

REASONS FOR PERFORMING STUDY: Centesis of the bicipital bursa using an 8.9 cm long spinal needle has been reported but the alternative of employing a 3.8 cm long hypodermic needle requires validation. OBJECTIVE: To compare the efficacy of 2 different methods of centesis of the bicipital bursa and to evaluate the usefulness of ultrasonographic imaging to determine the location of solution administered when centesis of the bursa is attempted. METHODS: For Trial 1, 6 clinicians, who had no previous experience of centesis of the bicipital bursa, attempted to inject a solution composed of an aqueous radiopaque contrast medium and physiological saline solution (PSS) into the bicipital bursae of 2/12 horses using the previously described distal approach to inject one bursa and a proximal approach to inject the contralateral bursa. The bicipital tendon and bursa were examined ultrasonographically before and after injection; and both shoulders were examined radiographically to identify the location of the medium. In Trial 2, another 6 clinicians, also with no previous experience of centesis, repeated Trial 1, using 6 horses, but the radiopaque contrast medium was mixed with air instead of PSS. RESULTS: Accuracy of centesis using the proximal approach was 39% and that of the distal approach 28%. Ultrasonographic examination of the shoulder allowed the location of solution and air to be accurately predicted in all 12 shoulders examined. CONCLUSIONS: Clinicians who have had no previous experience performing centesis of the bicipital bursa are unlikely to be successful in centesis using either approach. Radiographic examination after injecting a radiopaque contrast medium may be necessary to assess the success of centesis especially if bursal fluid is not obtained during centesis. Injecting air along with the radiopaque contrast medium provides more accurate ultrasonographic confirmation of centesis and better radiographic definition than does injection without air.     

不同样本商品蜂蜜中硒含量的测定

用硝酸和高氯酸消化蜂蜜,使硒游离出来,在微酸性环境下,硒和2,3-二氨基萘(DAN)生成有较强荧光的物质,用环己烷萃取,在激发波长378nm,荧光波长518nm处测定其荧光强度。蜂蜜中硒含量范围:0.10～0.82μg/g。表明:蜂蜜应视为天然富硒营养品。     

乳酸杆菌益生作用机制的研究进展

乳酸杆菌作为益生菌广泛用于人和动物。本文综述了乳酸杆菌改善宿主健康的机制。乳酸杆菌可通过产生抗菌物质如乳酸、过氧化氢、细菌素,或者通过竞争营养或肠道黏附位点来抑制致病菌;通过诱导黏附素的分泌或阻止细胞凋亡而增强肠道的屏障功能,从而保护肠道。文章重点讨论了乳酸杆菌表面成分（表面蛋白、脂磷壁酸和肽聚糖）与肠道受体（Ｃ型凝集素受体、Ｔｏｌｌ样受体和 Ｎｏｄ样受体）,阐述了他们结合后启动免疫调节信号,调控肠道免疫功能以发挥改善健康作用的机制。     

Effects of size of ingestively masticated fragments of plant tissues on kinetics of digestion of NDF

Ingestively masticated fragments were collected and sized via sieving. Different sizes of esophageal masticate and ruminal digesta fragments, and ground fragments of larger masticated pieces were incubated in vitro, and undigested NDF remaining at intervals of up to 168 h of incubation was determined. The ruminal age-dependent time delay (tau) for onset of digestion of NDF was positively correlated (P < 0.004) with the mean sieve aperture estimated to retain 50% of the fragments between successive sieve apertures (MRA). Degradation rate of potentially degradable NDF (PDF) and level of indigestible NDF were not related (P > 0.10) to MRA of masticated and ground fragments. Estimates of tau were positively related to MRA, with slopes of bermudagrass < corn silage < ruminal fragments of corn silage. It was concluded that fragment size-, and consequently, ruminal age-dependent onset of PDF degradation of a mixture of different fragment sizes results in an age-dependent rate of degradation of the more rapidly degrading of two subentities of PDF. Models are proposed that assume a tau before onset of simultaneous degradation of PDF from two pools characterized as having gamma-modeled age-dependency and age-constant rates. The ruminal age-dependent pool seems to be associated with the faster-degrading pool, and its rate parameter increases with range in MRA in the population of fragments. Conceptually, the ruminal age-dependent rate parameter for PDF degradation seems to represent a composite of several effects: 1) effects of the size-dependent tau; 2) range in MRA of the population of ingestively masticated fragments; and 3) subentities of PDF that degrade via more rapid age-dependent rates compared with subentities of PDF that degrade via age-constant rates. The estimated fractional rates of ruminative comminution of ingestively masticated fragments (0.060 to 0.075/h) were of a magnitude similar to the mean fractional rates of PDF digestion (0.030 to 0.085/h), which implies that ruminative comminution may be first-limiting to fractional rate of PDF digestion. The in vivo roles of ingestive and ruminative mastication of fragments on PDF degradation must be considered in any kinetic system for estimating PDF digestion in the rumen. These results and others in the literature suggest that the rate of surface area exposure rather than intrinsic chemical attributes of PDF may be first-limiting to degradation rate of PDF in vivo.     

Mechanism of Action of Probiotic Function of Lactobacilli

乳酸杆菌作为益生菌广泛用于人和动物.本文综述了乳酸杆菌改善宿主健康的机制.乳酸杆菌可通过产生抗菌物质如乳酸、过氧化氢、细菌素,或者通过竞争营养或肠道黏附位点来抑制致病菌;通过诱导黏附素的分泌或阻止细胞凋亡而增强肠道的屏障功能,从而保护肠道.文章重点讨论了乳酸杆菌表面成分(表面蛋白、脂磷壁酸和肽聚糖)与肠道受体(C型凝集素受体、Toll样受体和Nod样受体),阐述了他们结合后启动免疫调节信号,调控肠道免疫功能以发挥改善健康作用的机制.     

中华人民共和国农业部公告 第267号

为贯彻落实《兽药生产质量管理规范》(简称《兽药GMP》),进一步推动兽药GMP实施进程,我部制定了《兽药生产质量管理规范检查验收办法》,现予公告。本公告自2003年6月1日起施行。附件:兽药生产质量管理规范检查验收办法二○○三年四月十日第一章 总则 第一条 为推动《兽药生产质量管理规范》(以下简称兽药GMP)的实施,规范兽药GMP检查验收工作,制定本办法。 第二条 农业部负责全国兽药GMP管理和检查验收工作;负责制修订兽药GMP检查验收管理规定;负责兽药GMP检查员队伍建设和监督管理工作,负责国际兽药贸易中GMP互认工作。 …