猪附红细胞体病综合防制技术

猪附红细胞体病可以侵害任何日龄的猪，仔猪病死率高，孕猪容易流产，育肥猪痊愈后生长缓慢。在预防上，主要采取土霉素和阿散酸拌料的方法，保护率达90%以上。在治疗上，采取注射复方914A或血虫清或血虫净和土霉素、阿散酸、安乃近与六甲氧拌料相结合的方法，治愈率达92%。同时重视治疗猪弓形病、猪链球菌病和胸膜肺炎等继发病，使该病的病死率大大降低。     

猪附红细胞体病的综合防治

从2003年开始,我镇较大范围发生猪附红细胞体病,本病发生于任何日龄的猪,仔病发病率较较高,育肥猪痊愈后生长缓慢,怀孕母猪易发生流产。在预防方面,采用土霉素和阿散酸拌料饲喂, 保护率可达90％以上。在治疗上采用血虫清(血虫净)和长效土霉素、安基比林肌注与阿散酸拌料喂治愈达97％。同时要重视对弓形虫病、链球菌病和胸膜肺炎等继发病的治疗,以降低死亡率。     

猪附红细胞体病综合防制技术

猪附红细胞体病可以侵害任何日龄的猪,仔猪病死率高,孕猪容易流产,育肥猪痊愈后生长缓慢。在预防上,主要采取土霉素和阿散酸拌料的方法,保护率达90%以上。在治疗上,采取注射复方914A或血虫清或血虫净和土霉素、阿散酸、安乃近与六甲氧拌料相结合的方法,治愈率达92%。同时重视治疗猪弓形体病、猪链球菌病和胸膜肺炎等继发病,使该病的病死率大大降低。     

波尔山羊附红细胞体病并发砷中毒的诊治

1、发病情况。2005年2月12日，蓬莱市某养羊专业户从外地购进波尔山羊186只，其中羔羊134只、种公羊1只、种母羊51只。3日内发病73只、流产9窝。主要表现为发热，精神沉郁、食欲初期减退、后期废绝、排干粪，当时怀疑是附红细胞体病。先是自行用阿散酸治疗，500mg／kg拌料喂服3d，症状不减，误认为用量不足，逐加量至1500mg／kg拌料又喂服3d，结果症状加重，死亡18只。根据临床症状、病理变化、治疗用药（阿散酸）分析及血液检查结果，初步诊断为附红细胞体病并发砷中毒。     

四种药物对规模化猪场自然感染附红细胞体病的疗效观察

为了解京鑫养猪场附红细胞体的感染情况，并制定合理的用药方案，于2003年6月份对全场猪只附红细胞体感染情况做了调查，调查结果表明本场猪群附红细胞体感染率达90％以上，为此，选自然感染附红细胞体的断奶仔猪60头，随机分成6组，每组10头，分别用血虫净0．25ml／kg，金光1号0．2ml／kg，复方914A0．3ml／kg，附红弓清0．3ml／kg，肌肉注射；阿散酸拌料200g／t。结果显示治疗附红细胞体病最有效的药物是复方914A，其次是血虫净。     

一起肥育猪弓形虫病的诊治

1　发病情况河南省郸城县一存栏 3 0 0头育肥猪的猪场在2 0 0 2年 1月 1 5日 ,肥育猪出现以发热、腹泻、呼吸困难、后肢踉跄为特征的疫病。首次发病两头误诊为附红细胞体病 ,用血虫净肌注 ,金霉素、阿散酸拌料治疗 ,并无好转。在随后一周内 ,陆续有 46头猪出现类似症状 ,并有 2     

治疗猪附红细胞体病用这些药

四环素、卡那霉素、强力霉素、土霉素、黄色素、血虫净(贝尼尔)、氯苯胍、砷制剂(阿散酸)等可用于治疗猪附红细胞体病,四环素和砷制剂效果较好。对猪附红细胞体病进行早期及时治疗可收到很好的效果。     

四种药物对规模化猪场自然感染附红细胞体病的疗效观察

为了解京鑫养猪场附红细胞体的感染情况,并制定合理的用药方案,于2003年6月份对全场猪只附红细胞体感染情况做了调查,调查结果表明本场猪群附红细胞体感染率达90%以上,为此,选自然感染附红细胞体的断奶仔猪60头,随机分成6组,每组10头,分别用血虫净0.25ml/kg,金光1号0.2ml/kg,复方914A0.3ml/kg,附红弓清0.3ml/kg,肌肉注射;阿散酸拌料200g/t。结果显示治疗附红细胞体病最有效的药物是复方914A,其次是血虫净。     

宁夏猪附红细胞体病诊治

宁夏中宁等县市区个体养猪户的猪出现以败血性出血和两耳、胸前、腹下、四肢皮肤呈现紫绀为特征的疾病,并引起猪群,尤其是仔猪大批死亡.经临床观察、病理剖检、实验实检查,确诊为猪附红细胞体病.经用金霉素、土霉素拌料饲喂,肌注血虫净及后期用强力霉素拌料喂服和肌注磷酸伯氨喹、青蒿素,病情获控制.     

猪附红细胞体病并发砷中毒的诊治

2003年11月，沂南一养猪场，400余头青年猪进猪3天全部发病，主要表现为高烧，精神沉郁，食欲废绝，拉干粪，用青霉素、安乃近等药物治疗后，症状减轻，但停药即反复。当地兽医怀疑是附红细胞体病，令其用阿散酸治疗，先是150mg／kg拌料3天，见症状得不到缓解，遂加量至1000mg／kg，结果病情加重，现已死亡10余头，后来我院就医。     

Successful treatment of recurrent subclinical mastitis in cows caused by enrofloxacin resistant bacteria by means of the sequential intramammary infusion of enrofloxacin HCl-2H2O and ceftiofur HCl: a clinical trial

BackgroundRecurrent subclinical mastitis (RScM) due to resistant bacteria has low clinical and bacteriological cure rates, often requiring the culling of cows. The sequential intra-mammary administration of enrofloxacin hydrochloride-dihydrate (enro-C) followed by ceftiofur HCl may be useful for treating these cases.ObjectivesThis study assessed the bacteriological and clinical cure-efficacies of the sequentially intramammary administration of enro-C, followed by ceftiofur HCl to treat RScM in Holstein/Friesian cows.MethodsThis trial was conducted in a herd with a high prevalence of RScM, and 20 Holstein/Friesian cows were included: 45% suffering subclinical mastitis and 38.9% of the mammary quarters affected. Twenty-nine bacterial isolates in vitro resistant to enro-C were obtained (coagulase-negative Staphylococcus spp, 55.2%; Staphylococcus aureus, 27.6%; Escherichia coli, 6.9%; Streptococcus uberis, 6.9%; Corynebacterium bovis, 3.4%). Polymerase chain reaction-isolated the following genes linked to enro-C resistance: chromosomal (gyrA) and plasmid (aac(6'')-lb-cr). The treatments were as follows: twice-daily intramammary infusions of enro-C (300 mg/10 mL) for 5 days. Cows clinically considered treatment failures were also treated with intramammary ceftiofur (125 mg/10 mL, twice daily for 5 days. The clinical and bacteriological cure rates were carried out when completing each treatment phase and at 14 and 21 days, aided by a California mastitis test, somatic cell count, and failure to identify the initially causative bacteria.ResultsEnro-C achieved 65% clinical and bacteriological cure rates, and 100% cure rates were obtained after the rescue treatment with ceftiofur HCl.ConclusionsOutstanding clinical and bacteriological cure rates in cows affected by RScM were achieved with the consecutive intramammary infusions of enro-C, followed by ceftiofur HCl.     

藿芪灌注液治疗奶牛卵巢静止和持久黄体的临床试验

将确诊为患持久黄体和卵巢静止的病牛各40头,随机分为4组,分别为藿芪灌注液高、中(推荐剂量)、低剂量治疗组和促孕灌注液对照治疗组,每组10头。试验组每头牛分别按每次150mL、100mL和50mL的剂量子宫灌服,隔日1次,4次为1个疗程。对照药物治疗组为促孕灌注液,每次100 mL,隔日1次,4次为1个疗程。结果显示,用藿芪灌注液治疗奶牛持久黄体的高、中、低剂量组的治愈率分别是80%、70%和50%,总有效率分别是90%、90%和60%。对照组治愈率80%,总有效率90%。高剂量组、中剂量组和对照组的治愈率和总有效率均显著高于低剂量组(P0.05),高剂量组与中剂量组之间无显著性差异(P0.05),藿芪灌注液高、中剂量组与对照药物组之间无显著差异(P0.05)。用藿芪灌注液治疗奶牛卵巢静止高、中、低剂量组的治愈率分别是90%、80%和60%,总有效率分别是100%、100%和70%;对照组治愈率80%,总有效率90%,高剂量组、中剂量组和对照组的治愈率和总有效率均显著高于低剂量组(P0.05),高剂量组与中剂量组之间无显著性差异(P0.05),高、中剂量组与对照组之间无显著差异(P0.05)。     

复方吡喹酮注射液防治羊脑多头蚴病的试验研究

为了获得复方吡喹酮注射液治疗羊脑多头蚴病的最佳治疗剂量,本试验应用复方吡喹酮注射液30、50、80 mg/kg BW三个剂量组对患羊脑多头蚴病的绵羊进行治疗,设80 mg/kg BW剂量的丙硫咪唑作为药物对照组.试验结果表明,30 mg/kg BW剂量组治愈率较低,为68.97%,不能达到治疗目的;50和80 mg/kg BW剂量对羊脑多头蚴均有很强的驱杀作用,对病羊的治愈率分别为91.84%和92.85%,但两组间差异不显著(P＞0.05);高、中剂量组(80、50 mg/kg BW)与低剂量组、药物对照组比较差异极显著(P＜0.01).50 mg/kg BW剂量为防治羊脑多头蚴病的最佳治疗剂量.     

Efficacy of two antibiotic treatments in curing clinical and subclinical mastitis in lactating dairy cows

AIM: To compare the bacteriological and clinical cure rates for clinical and subclinical mastitis in New Zealand dairy cows following treatment with either an intramammary penicillin-dihydrosptreptomycin preparation or a subcutaneous injection of penethamate hydriodide. METHODS: Milk samples were collected from clinical and subclinical cases of mastitis before and 14 and 21 days after initiation of treatment for bacteriological culture, somatic cell count determination and conductivity testing. RESULTS: No significant differences in the bacteriological cure rate of major Gram-positive pathogens, clinical cure rate, somatic cell count or conductivity were found between treatments. However, the bacteriological cure rate of coagulase-negative staphylococcus infections and the overall bacteriological cure rate was lower for quarters treated with penethamate than with penicillin-dihydrosptreptomycin. CONCLUSIONS: The bacteriological cure rate of mastitis caused by major Gram-positive pathogens, the clinical cure rate, somatic cell count and conductivity did not differ between the two antibiotic treatments. .     

Field trials with a killed, nine-strain, oil adjuvanted Bacteroides nodosus footrot vaccine in sheep

Field trials were set up on five properties to determine the cure and protection rates of a killed, nine-strain, oil adjuvanted Bacteriodes nodosus footrot vaccine, under natural conditions. Foot infections were scored at the time of the first vaccination and at approximately four weeks and ten weeks later. Cure rates were 34-47% for vaccinated sheep, and 18-47% for untreated sheep. Using the Australian Licensing Authorities calculation, the cure rates for the vaccine ranged from -40% to 44%. A lack of suitable conditions for spread of footrot meant that protection rates could not be determined.     

菌速灭对鸡白痢的临床疗效观察

为了评价人工合成的新兽药“菌速灭”不同剂量对沙门菌所致鸡白痢的临床疗效,采用“菌速灭”高、中、低3个剂量组及药物对照组通过饮水给药方式治疗雏鸡白痢,并与感染、健康对照组进行临床治疗效果比较。结果表明,“菌速灭”高、中剂量组治愈率和相对增重率效果均优于诺氟沙星,能较好的治疗雏鸡白痢。     

Efficacy of two antibiotic treatments in curing clinical and subclinical mastitis in lactating dairy cows

Aim. To compare the bacteriological and clinical cure rates for clinical and subclinical mastitis in New Zealand dairy cows following treatment with either an intramammary penicillin-dihydrosptreptomycin preparation or a subcutaneous injection of penethamate hydriodide.

Methods. Milk samples were collected from clinical and subclinical cases of mastitis before and 14 and 21 days after initiation of treatment for bacteriological culture, somatic cell count determination and conductivity testing.

Results. No significant differences in the bacteriological cure rate of major Gram-positive pathogens, clinical cure rate, somatic cell count or conductivity were found between treatments. However, the bacteriological cure ralte of coagulase-negative staphylococcus infections and the overall bacteriological cure rate was lower for quarters treated with penethamate than with penicillin-dihydrosptreptomycin.

Conclusions. The bacteriological cure rate of mastitis caused by major Gram-positive pathogens, the clinical cure rate, somatic cell count and conductivity did not differ between the two antibiotic treatments.     

盐酸沃尼妙林预混剂的研制及其对猪增生性肠的炎疗效观察

以盐酸沃尼妙林为原料,利用流化床制粒包衣技术成功制备微丸型盐酸沃尼妙林预混剂,用HPLC测定制剂中主药含量。结果表明,制得的产品粒度均匀、流动性良好、含量稳定。选用猪增生性肠炎的自然发病猪为试验对象,以延胡索酸泰妙菌素疗效为对照。结果显示,试验组的高中低不同剂量组(中剂量为推荐剂量)与对照组对猪增生性肠炎治愈率分别为91.0%、82.0%、66.7%和75.3%,有效率分别为96.7%、88.7%、76.7%和83.6%,相同推荐剂量的微丸型盐酸沃尼妙林预混剂组的治愈率和有效率均高于泰妙菌素预混剂组(P<0.05)。     

2014-2016年广州市屠宰场分离沙门氏菌血清学鉴定和耐药性分析

2014-2016年从广州市屠宰场分离沙门氏菌151株,鉴定出12种血清型,前3位优势血清型分别为德尔卑沙门氏菌、罗森氏沙门氏菌、鼠伤寒沙门氏菌。采用微量肉汤稀释法测定分离菌株对13种抗菌药物的敏感性。结果显示,沙门氏菌对四环素、多西环素、磺胺异恶唑、氨苄西林、大观霉素的耐药率都在60%以上,对奥格门丁、恩诺沙星、氧氟沙星、头孢噻呋、多粘菌素E敏感（耐药率≤16%）。多重耐药率为79.20%。研究表明,沙门氏菌对部分药物耐药性较严重,亟需加强养殖业抗菌药物的合理应用以控制耐药性的发展。     

Efficacy of a 5-day extended therapy program during lactation with cephapirin sodium in dairy cows chronically infected with Staphylococcus aureus

This study determined the efficacy of a 5-day extended therapy with cephapirin sodium in dairy cows chronically infected with Staphylococcus aureus. Chronically infected cows selected from 14 dairy herds in the St-Hyacinthe region, Québec were randomly allocated to a group of 31 cows treated for 5 consecutive days with 200 mg of cephapirin per quarter BID or a group of 30 untreated control cows. Bacteriological cure was determined by 3 negative bacterial cultures at 10, 24, and 31 days after treatment. The cow cure rates were 25.8% (8/31) in the treated cows and 3.3% (1/30) in the control group (P = 0.013). The quarter cure rates at first sampling post-treatment were 77.6% (38/49) and 18% (9/50) in the treated and the control groups, respectively (P < 0.0001). A 5-day extended therapy with cephapirin is effective in treating cows chronically infected with S. aureus.