共查询到16条相似文献,搜索用时 15 毫秒
1.
2.
Andrew Plant Achim Harder Norbert Mencke Heinz-Jürgen Bertram 《Pest management science》1996,48(4):351-358
7-Hydroxy-5-oxo-5H-thieno[3,2-b]pyran-6-carboxanilides and -6-thio-carboxanilides represent a novel series of anthelmintic compounds, with broad-spectrum activity against important parasitic nematodes in sheep and dogs. In particular, an improved efficacy against Trichostrongylus colubriformis in sheep over the related 3-carbamoyl-4-hydroxycoumarins has been noted. New synthetic routes to the key intermediate, 7-hydroxythieno[3,2-b]pyran-5-one, have been developed. 相似文献
3.
4.
5.
Chiara B. Vicentini Tiziana Poli Augusto C. Veronese Vincenzo Brandolini Maurizio Manfrini Mario Guarneri Paolo Giori 《Pest management science》1989,27(1):77-83
Twelve 6-trifluoromethylpyrazolo[3,4-d]pyrimidin-4(5H)-thiones were prepared by the reaction between 4-thiocarbamoyl-5-aminopyrazoles and trifluoroacetic anhydride. They were tested in vitro for antifungal activity against a series of phytopathogenic fungi of different taxonomic classes. The EC50 and MIC values of four compounds were comparable or inferior to those of reference commercial fungicides in controlling Sclerotinia minor, Corticium solani and Phytium ultimum. 相似文献
6.
In order to identify the factors providing the triazolopyrimidines with a wide range of selectivity amongst agriculturally important plant species, studies were made on the uptake and metabolism of a representative compound, N-(2,6-dichlorophenyl)-5,7-dimethyl-1,2,4-triazolo[1,5-a]pyrimidine- 2-sulfonamide. This compound is much more phytotoxic to dicots than to monocots. Experiments showed that variations in leaf morphologies and geometries relative to spray applications resulted in different herbicide dosages applied to plant species used in selectivity evaluations. However, this parameter did not have a statistically significant correlation to herbicide selectivity measurements. Characterization of the metabolic pathways showed that the major herbicide metabolites involved methyl hydroxylation or hydroxylation of the aniline ring followed by glucose conjugation. Since these metabolites were not exclusive to either monocots or dicots, herbicide selectivity does not appear dependent on the pathway of metabolism. Studies on the kinetics of metabolism suggest instead that metabolic rate was important. Monocots metabolized the herbicide rapidly and generally were tolerant while the opposite was true of dicots. 相似文献
7.
8.
Nobuyuki Okajima Isao Aoki Yoshiyuki Okada Toshio Fujita 《Pest management science》1991,32(3):265-273
Potent herbicidal ethyl 5-[N-(5,7-dimethoxy2H-1,2,4-thiadiazolo-[2,3-a] pyrimidin-2-ylidene)sulfamoyl]-1,3-dimethylpyrazole-4-carboxylate (I) was hydrolyzed under weakly basic conditions to afford a sulfonylurea (VII) , a 2-pyrimidylcyanamide (IV) and a mercaptopyrazole (VI) . The formation of these products was explained by nucleophilic attack at the 1 and 2-positions of the 1,2,4-thiadiazolo[2,3-alpyrimidine ring. This is believed to mimic the process which occurs on application to the plant. I appears to be a pro-pesticide for the sulfonylurea, VII . 相似文献
9.
10.
Bok Ryul Yoo Mi Yeon Suk Joon Soo Han Yong-Man Yu Soon-Gyu Hong Il Nam Jung 《Pest management science》1998,52(2):138-144
A series of 1-aryl-1-(1H-1,2,4-triazol-1-yl)alkyl-1-silacyclopentanes has been synthesized by four-step reactions starting from 1-chloroalkyltrichlorosilane and tested for fungicidal activities in vitro for ten fungi and in vivo for four fungi occurring in rice, cucumber, tomato etc. Biological activities of the title compounds are strongly dependent upon the p-substituent on the phenyl group in the following order: F>Cl>Ph>OEt>H. Especially, 1-p-fluorophenyl-1-[1-(1H-1,2,4-triazol-1-yl)alkyl]-1-silacyclopentanes (alkyl=methyl or ethyl) showed significant fungicidal activity with a broad spectrum comparable to flusilazole in in-vivo assay. © 1998 SCI. 相似文献
11.
以3-(3-三氟甲基苯基)-丙烯酸为起始原料,设计并合成了14个4-取代-2-(3-三氟甲基)苯乙烯基-1,3,4-噁二嗪-5-酮衍生物,其化学结构经核磁共振氢谱及元素分析确证。初步的生物活性测定结果表明,该类化合物具有良好的杀虫活性,其中化合物 D-2,D-3,D-4,D-8 在质量浓度为50 mg/L时,对淡色库蚊Culex pipiens pallens的致死率分别为91.7% ,86.1% ,85.5%和93.9%。 相似文献
12.
13.
Maria J. Gil Jos M. Zabalza Javier Navarro Maria A. Maú Alberto Gonzlez Víctor Martínez Merino Arantxa Canal Mercedes Royuela Pedro M. Aparicio-Tejo 《Pest management science》1997,49(2):148-156
Several ethyl 2,3-dihydro-3-oxoisothiazolo[5,4-b]pyridine-2-alkanoate derivatives were synthesized as herbicides. Only 5-methyl derivatives inhibited both hypocotyl and root growth in the lettuce (Lactuca sativa L.) seedling test at 100 mg litre-1. Only ethyl propionate and valerate derivatives showed significant inhibition at 0·1 mg litre-1, whereas ethyl acetate or butyrate derivatives were inactive. Contrary to unoxidized derivatives, the inhibitory effect of 1-oxide and 1,1-dioxide derivatives was strongly dependent on concentration; ethyl 2,3-dihydro-5-methyl-3-oxoisothiazolo[5,4-b]pyridine-2-propionate 1,1-dioxide inhibited 100% of germination at 100 mg litre-1 and 45% of lettuce seedling growth at 0·1 mg litre-1. Quantitative structure–inhibition of growth relationship analysis carried out by adaptive least-squares (ALS) method gave a good correlation with small and hydrophobic 5-substituents as well as with odd carbon-chain ethyl alkanoates in position 2. Active compounds did not show auxin-like activity from 0·1 to 100 mg litre-1. © 1997 SCI. 相似文献
14.
Barbosa LC de Alvarenga ES Demuner AJ Figueiredo R da Silva AA 《Pest management science》2003,59(9):1043-1051
Several new compounds with potential herbicidal activity were synthesized from 2alpha,4alpha-dimethyl-6,7-exo-isopropylidenedioxy-8-oxabicyclo[3.2.1]octan-3-one (4). Seven aromatic alcohols were prepared by reaction of (4) with aryllithium reagents, where the aryl groups were 4-ethoxyphenyl (5, 70% yield), 4-ethylphenyl (6, 82% yield), 4-butylphenyl (7, 78% yield), 4-tert-butylphenyl (8, 81% yield), 2,4-dimethoxyphenyl (9, 75% yield), 2-ethylphenyl (10, 12% yield) and para-(4-bromophenoxy)phenyl (11, 24% yield). Reaction of the acetonide (4) with Grignard reagents formed also four aliphatic alcohols where the alkyl groups are ethyl (13, 78%), butyl (14, 85%), hexyl (15, 81%) and octyl (25, 92%). The alcohols (5), (6), (7), (8), (13), (14), (15) and (25) were reacted with thionyl chloride in pyridine, forming their respective alkenes (17, 76%), (18, 74%), (19, 83%), (20, 73%), (22, 78%), (26, 62%), (23, 77%) and (24, 66%). The effect of these compounds, at the concentration of 5.5 microg g(-1), on the development of radicle and aerial parts of Sorghum bicolor (L) Moench, Euphorbia heterophylla L, Brachiaria decumbens and Desmodium tortuosum DC was evaluated. 相似文献
15.
A series of 2-alkyl-7, 8-dihydro-3-hydroxynaphtho[1,2-c]chromen-6-ones was synthesised by the condensation of ethyl 3, 4-dihydro-1-oxonaphthalene-2-carboxylate with substituted phenols in the presence of POCl3. The compounds were characterised and tested for their toxicity towards the mycelial growth of seven phytopathogenic fungi in culture. Drechslera oryzae, Rhizoctonia solani and Colletotrichum falcatum exhibited maximum sensitivity to these compounds whereas Macro-phomina phaseolina, Fusarium solani, Alternaria alternata and Pythium aphanidermatum were less sensitive. 2-Ethyl-7, 8-dihydro-3-hydroxy-naphtho[1,2-c]chromen-6-ones possessed greatest toxicity with EC50 values ranging from 0.2 to 2.5 μg ml?1 against all fungi except A. alternata and P. aphanidermatum. 相似文献
16.
Kiran YB Gunasekar D Devendranath Reddy C Suresh Reddy C Tran K Le T Berlin KD Srinivasan S Charitha Devi M 《Pest management science》2005,61(10):1016-1023
Several new substituted oxazaphosphorinyl urea derivatives of the type RR'P(O)NHC(O)NHR' were synthesized from alpha-(3-chloro-4-fluoroanilino)-o-cresol by reaction with chlorides of aryl/alkyl/cyclohexyl carbamidophosphoric acids in the presence of triethylamine at 0-50 degrees C. Their significant insecticidal and antimicrobial activity and promotion of Rhizobium bacteria growth in the soil without effect on the host tissue suggests their possible commercial application as ecofriendly pesticides and antimicrobial agents. 相似文献