Sulfur in pesticide action and metabolism: Edited by J. D. Rosen,P. S. Magee,and J. E. Casida,American Chemical Society,Washington, D.C., 1981. 172 pp., $33.00

The distribution of ¹⁴C-acid-, ¹⁴C-alcohol-, and ¹⁴C-cyano-labeled deltamethrin and selected metabolites were followed in the liver, blood, cerebrum, cerebellum, and spinal cord after iv administration of a toxic, but nonlethal dose (1.75 mg/kg) to rats. Approximately 50% of the dose was cleared from the blood within 0.7–0.8 min, after which the rate of clearance decreased. 3-Phenoxybenzoic acid (PBacid) was isolated from the blood in vivo, and was also the major metabolite when ¹⁴C-alcohol-labeled deltamethrin was incubated with blood in vitro. Deltamethrin levels in the liver peaked at 7–10 nmol/g at 5 min and then decreased to 1 nmol/g by 30 min. In contrast, peak central nervous system levels of deltamethrin were achieved within 1 min (0.5 nmol/g), decreasing to 0.2 nmol/g at 15 min, and remaining stable until 60 min. peak levels of deltamethrin did not correspond to the severity of toxicity, although the levels of non-pentane-soluble radiolabel did appear to correlate with motor signs of toxicity. Experiments with brain homogenates, using in vivo concentrations of deltamethrin, failed to reproduce the pentane-unextractable radioactivity in vitro nor was any metabolism demonstrated.     

Intestinal helminths from grey mullets, Mugil capito Cuv. and M. cephalus L., of Lake Borullus, A.R.E.

Helminthological examination of grey mullets, Mugil capito Cuv. and M. cephalus L. from brackish Lake Borullus in the Nile Delta in the Lower Egypt revealed that these fishes are infected with two species of digenetic trematodes, Haplosplanchnus pachystoma (Eysenhardt, 1829) and Saccocoelium obesum Loos, 1902 and one acanthocephalan species, Neoechinorhynchus agilis (Rudolphi, 1819). On comparing the incidence and intensity of infection of individual fish samples it was found that after migration from the sea to the lake the grey mullets lose gradually their intestinal trematodes.